Schlundt lab
@lab-nmr.bsky.social
Group 'Analytical Biochemistry' at the Institute of Biochemistry at the University of Greifswald.
We are studying protein nucleic acid interactions with a focus on NMR-based methodology.
We are studying protein nucleic acid interactions with a focus on NMR-based methodology.
Reposted by Schlundt lab
One hundred thousand people a year and y'all using past tense when you talk about Covid now jfc
Covid-19 Is Still Killing a Disturbing Number of Americans, Study Finds
Between 2022 and 2024, covid-19 killed roughly 100,000 Americans annually, new research by CDC scientists shows.
gizmodo.com
January 6, 2026 at 10:51 PM
One hundred thousand people a year and y'all using past tense when you talk about Covid now jfc
Very nice work! Congratulations!
Our latest work is now out in @cp-molcell.bsky.social !
We have looked at Sgt1, an essential Hsp90 co-chaperone in yeast. We determined its interaction with Hs90 and showed that it stabilises the chaperone-client complex and prevents its dissociation by Aha1.
www.cell.com/molecular-ce...
We have looked at Sgt1, an essential Hsp90 co-chaperone in yeast. We determined its interaction with Hs90 and showed that it stabilises the chaperone-client complex and prevents its dissociation by Aha1.
www.cell.com/molecular-ce...
January 7, 2026 at 1:02 PM
Very nice work! Congratulations!
Reposted by Schlundt lab
Protein Science, Review, Unfolding the history of protein HDX NMR, Jordyn M. Markle, University of North Carolina at Chapel Hill onlinelibrary.wiley.com/doi/10.1002/... @proteinsociety.bsky.social #NMRchat #NMR 🧲
Unfolding the history of protein HDX NMR
I review the development of two-dimensional hydrogen-deuterium exchange (HDX) nuclear magnetic resonance (NMR) spectroscopy and highlight its importance to the study of protein structure and stabilit...
onlinelibrary.wiley.com
December 29, 2025 at 2:13 PM
Protein Science, Review, Unfolding the history of protein HDX NMR, Jordyn M. Markle, University of North Carolina at Chapel Hill onlinelibrary.wiley.com/doi/10.1002/... @proteinsociety.bsky.social #NMRchat #NMR 🧲
Congratulations to the Wöhnert lab! Should and will be highly-cited work! Worth reading! 🍾👍
⭐NAR Breakthrough! ⭐
🧬 A synthetic RNA forms a #G-quadruplex without a G-rich sequence, using a complex 3D fold and GTP as a ligand. This suggests G-quadruplexes may be far more widespread in biologically important RNAs. Read more: doi.org/10.1093/nar/...
#NARBreaktrhough #RNA #StructuralBiology
🧬 A synthetic RNA forms a #G-quadruplex without a G-rich sequence, using a complex 3D fold and GTP as a ligand. This suggests G-quadruplexes may be far more widespread in biologically important RNAs. Read more: doi.org/10.1093/nar/...
#NARBreaktrhough #RNA #StructuralBiology
December 24, 2025 at 6:09 PM
Congratulations to the Wöhnert lab! Should and will be highly-cited work! Worth reading! 🍾👍
Reposted by Schlundt lab
🚨Paper Alert🚨
We found a novel transcription factor function of the zinc finger protein “Hangover” in the regulation of Drosophila gene expression🪰🧬:
doi.org/10.1093/nar/...
#chromatin #transcription #hangover #histone modification #NSL complex
A thread:
We found a novel transcription factor function of the zinc finger protein “Hangover” in the regulation of Drosophila gene expression🪰🧬:
doi.org/10.1093/nar/...
#chromatin #transcription #hangover #histone modification #NSL complex
A thread:
Hangover regulates gene expression by limiting NSL-mediated H4K16 acetylation
Abstract. The RNA-binding protein Hangover (Hang) is essential for several stress responses in Drosophila melanogaster. Here, we discover a novel function
doi.org
December 18, 2025 at 12:42 PM
🚨Paper Alert🚨
We found a novel transcription factor function of the zinc finger protein “Hangover” in the regulation of Drosophila gene expression🪰🧬:
doi.org/10.1093/nar/...
#chromatin #transcription #hangover #histone modification #NSL complex
A thread:
We found a novel transcription factor function of the zinc finger protein “Hangover” in the regulation of Drosophila gene expression🪰🧬:
doi.org/10.1093/nar/...
#chromatin #transcription #hangover #histone modification #NSL complex
A thread:
Reposted by Schlundt lab
Our structure determination of a dopamine-binding DNA aptamer yielded surprising results. The structure had only 2 Watson-Crick base pairs, but lots of base pairs normally only seen in RNA folds. Check out our crazy DNA structure in the recent bioRxiv preprint, along with other binding details.
December 3, 2025 at 9:41 PM
Our structure determination of a dopamine-binding DNA aptamer yielded surprising results. The structure had only 2 Watson-Crick base pairs, but lots of base pairs normally only seen in RNA folds. Check out our crazy DNA structure in the recent bioRxiv preprint, along with other binding details.
Reposted by Schlundt lab
Our latest work is out! We combined #NMR with #Crystallography, #MD, and #ProteinMPNN to analyze the conformational dynamics of a de novo enzyme and redesigned it! Great collaboration between
@cathleenzeymer.bsky.social and the @sattler-lab.bsky.social.
www.cell.com/structure/fu...
@cathleenzeymer.bsky.social and the @sattler-lab.bsky.social.
www.cell.com/structure/fu...
November 17, 2025 at 11:28 AM
Our latest work is out! We combined #NMR with #Crystallography, #MD, and #ProteinMPNN to analyze the conformational dynamics of a de novo enzyme and redesigned it! Great collaboration between
@cathleenzeymer.bsky.social and the @sattler-lab.bsky.social.
www.cell.com/structure/fu...
@cathleenzeymer.bsky.social and the @sattler-lab.bsky.social.
www.cell.com/structure/fu...
Reposted by Schlundt lab
Prof. Dr. Uwe Bornscheuer wurde in die acatech - Deutsche Akademie der Technikwissenschaften als Mitglied berufen. Das beschloss die Mitgliederversammlung im Oktober 2025. Es ist eine von Bund und Ländern geförderte nationale Akademie. Herzlichen Glückwunsch!
📷️Laura Schirrmeister
#UniGreifswald
📷️Laura Schirrmeister
#UniGreifswald
October 29, 2025 at 9:00 AM
Prof. Dr. Uwe Bornscheuer wurde in die acatech - Deutsche Akademie der Technikwissenschaften als Mitglied berufen. Das beschloss die Mitgliederversammlung im Oktober 2025. Es ist eine von Bund und Ländern geförderte nationale Akademie. Herzlichen Glückwunsch!
📷️Laura Schirrmeister
#UniGreifswald
📷️Laura Schirrmeister
#UniGreifswald
A few more days to apply for open PhD and Postdoc positions! Interested in structural biochemistry of the host-virus interface? Then pick an interdisciplinary project around DNA, RNA, proteins and join our team! All fully funded!
Get in contact or apply here:
www.uni-greifswald.de/en/universit...
Get in contact or apply here:
www.uni-greifswald.de/en/universit...
Jobs - University of Greifswald
On this page you will find an overview of the current vacancies of the University of Greifswald.
www.uni-greifswald.de
October 28, 2025 at 8:33 AM
A few more days to apply for open PhD and Postdoc positions! Interested in structural biochemistry of the host-virus interface? Then pick an interdisciplinary project around DNA, RNA, proteins and join our team! All fully funded!
Get in contact or apply here:
www.uni-greifswald.de/en/universit...
Get in contact or apply here:
www.uni-greifswald.de/en/universit...
Postdoc position available, fully funded for 3y!!! The interdisciplinary project covers the structural biochemistry of a versatile nucleic acid binding protein in RNA-viral defense! The official job post can be found through our homepage:
biochemie.uni-greifswald.de/forschung/fo...
Or DM for more!
biochemie.uni-greifswald.de/forschung/fo...
Or DM for more!
Analytische Biochemie - Fakultät - Universität Greifswald
Universität Greifswald
biochemie.uni-greifswald.de
October 20, 2025 at 11:59 AM
Postdoc position available, fully funded for 3y!!! The interdisciplinary project covers the structural biochemistry of a versatile nucleic acid binding protein in RNA-viral defense! The official job post can be found through our homepage:
biochemie.uni-greifswald.de/forschung/fo...
Or DM for more!
biochemie.uni-greifswald.de/forschung/fo...
Or DM for more!
Highly recommended! Don't miss out!
Starting your own lab is exciting—but challenging.
Join our GBM Young Investigator leadership workshop in Regensburg, April 13–16th, 2026.
Professional coaching, peer networking & practical tips for new PIs.
Apply by Nov 30, 2025.
👉 gbm-online.de/de/young-inv...
Pls repost!
Join our GBM Young Investigator leadership workshop in Regensburg, April 13–16th, 2026.
Professional coaching, peer networking & practical tips for new PIs.
Apply by Nov 30, 2025.
👉 gbm-online.de/de/young-inv...
Pls repost!
October 15, 2025 at 6:03 PM
Highly recommended! Don't miss out!
We are hiring a PhD student!!
The project starts as early as January 2026 and is fully funded for three years.
Everyone with interest in NMR-centered structural biochemistry of nucleic acid-protein interactions in virus-infected cells, get in contact!
biochemie.uni-greifswald.de/forschung/fo...
The project starts as early as January 2026 and is fully funded for three years.
Everyone with interest in NMR-centered structural biochemistry of nucleic acid-protein interactions in virus-infected cells, get in contact!
biochemie.uni-greifswald.de/forschung/fo...
Analytische Biochemie - Fakultät - Universität Greifswald
Universität Greifswald
biochemie.uni-greifswald.de
October 7, 2025 at 12:03 PM
We are hiring a PhD student!!
The project starts as early as January 2026 and is fully funded for three years.
Everyone with interest in NMR-centered structural biochemistry of nucleic acid-protein interactions in virus-infected cells, get in contact!
biochemie.uni-greifswald.de/forschung/fo...
The project starts as early as January 2026 and is fully funded for three years.
Everyone with interest in NMR-centered structural biochemistry of nucleic acid-protein interactions in virus-infected cells, get in contact!
biochemie.uni-greifswald.de/forschung/fo...
Reposted by Schlundt lab
Want to connect with researchers in #GeneRegulation, small RNAs, #StructuralBiology and more? Sign up for EMBO Workshop "RNA-guided genome protection" in Caux, Switzerland, 16–20 June 2026!
Deadline: 15 March
meetings.embo.org/event/26-gen...
#DNAsky #RNAsky #EMBORNAGenomeProtection #EMBOevents 🧪
Deadline: 15 March
meetings.embo.org/event/26-gen...
#DNAsky #RNAsky #EMBORNAGenomeProtection #EMBOevents 🧪
RNA-guided genome protection
The genome carries information across generations, ensuring species survival. To preserve faithful transmission of genetic information, RNA-directed mechanisms safeguard the genome integrity in diver…
meetings.embo.org
October 6, 2025 at 3:06 PM
Want to connect with researchers in #GeneRegulation, small RNAs, #StructuralBiology and more? Sign up for EMBO Workshop "RNA-guided genome protection" in Caux, Switzerland, 16–20 June 2026!
Deadline: 15 March
meetings.embo.org/event/26-gen...
#DNAsky #RNAsky #EMBORNAGenomeProtection #EMBOevents 🧪
Deadline: 15 March
meetings.embo.org/event/26-gen...
#DNAsky #RNAsky #EMBORNAGenomeProtection #EMBOevents 🧪
Reposted by Schlundt lab
🌊🔍 Ministerin Bettina Martin besuchte die Universität Greifswald im Rahmen ihrer Sommertour 2025!
„Die hier aufgebaute wissenschaftliche Expertise ist ein absolutes Alleinstellungsmerkmal, nicht nur in Deutschland, sondern international“, sagte Wissenschaftsministerin Bettina Martin.
ugreif.de/uwcj7
„Die hier aufgebaute wissenschaftliche Expertise ist ein absolutes Alleinstellungsmerkmal, nicht nur in Deutschland, sondern international“, sagte Wissenschaftsministerin Bettina Martin.
ugreif.de/uwcj7
Moorkunde für Ministerin Martin - Universität Greifswald
Universität Greifswald
www.uni-greifswald.de
August 20, 2025 at 3:01 PM
🌊🔍 Ministerin Bettina Martin besuchte die Universität Greifswald im Rahmen ihrer Sommertour 2025!
„Die hier aufgebaute wissenschaftliche Expertise ist ein absolutes Alleinstellungsmerkmal, nicht nur in Deutschland, sondern international“, sagte Wissenschaftsministerin Bettina Martin.
ugreif.de/uwcj7
„Die hier aufgebaute wissenschaftliche Expertise ist ein absolutes Alleinstellungsmerkmal, nicht nur in Deutschland, sondern international“, sagte Wissenschaftsministerin Bettina Martin.
ugreif.de/uwcj7
Reposted by Schlundt lab
New publication in @narjournal.bsky.social - Using NMR, SAXS & MD, we characterize the dynamic nonaloop of the SARS-CoV-2 Delta s2m RNA, contributing to future ensemble-functional studies of dynamic RNA motifs.
Full text: doi.org/10.1093/nar/...
#RNA #StructuralBiology #NAR #NMR #MDSimulations
Full text: doi.org/10.1093/nar/...
#RNA #StructuralBiology #NAR #NMR #MDSimulations
Structural heterogeneity and dynamics in the apical stem loop of s2m from SARS-CoV-2 Delta by an integrative NMR spectroscopy and MD simulation approach
Abstract. In structured RNAs, helical elements are often capped by apical loops that are integral structural elements, ranging from 3 to >20 nts of size
doi.org
July 1, 2025 at 6:57 AM
New publication in @narjournal.bsky.social - Using NMR, SAXS & MD, we characterize the dynamic nonaloop of the SARS-CoV-2 Delta s2m RNA, contributing to future ensemble-functional studies of dynamic RNA motifs.
Full text: doi.org/10.1093/nar/...
#RNA #StructuralBiology #NAR #NMR #MDSimulations
Full text: doi.org/10.1093/nar/...
#RNA #StructuralBiology #NAR #NMR #MDSimulations
Reposted by Schlundt lab
Cool story - SOS splicing to remove transposons in mRNA! Though not by the spliceosome.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
An RNA Splicing System that Excises Transposons from Animal mRNAs
All genomes harbor mobile genetic parasites called transposable elements (TEs). Here we describe a system, which we term SOS splicing, that protects C. elegans and human genes from DNA transposon-medi...
www.biorxiv.org
June 28, 2025 at 9:11 AM
Cool story - SOS splicing to remove transposons in mRNA! Though not by the spliceosome.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
So deserved! Congratulations to the team! I guess we will get to see brilliant research... 👏
🎉 We’re absolutely thrilled: SCALE has been selected as a DFG Excellence Cluster!
A huge thank you to our incredible team—this would not have been possible without your dedication and talent. 🙌 @dfg.de
#ClustersOfExcellence #SCALEcluster 🧵
A huge thank you to our incredible team—this would not have been possible without your dedication and talent. 🙌 @dfg.de
#ClustersOfExcellence #SCALEcluster 🧵
May 23, 2025 at 7:03 PM
So deserved! Congratulations to the team! I guess we will get to see brilliant research... 👏
We are hiring:
Technical/lab assistance; permanent position, up to salary grade E9a! Close to the Baltic Sea in a newly establishing group.
Please get in contact for more information and see the official announcement (no German necessary though):
stellen.angebote.uni-greifswald.de/jobposting/6...
Technical/lab assistance; permanent position, up to salary grade E9a! Close to the Baltic Sea in a newly establishing group.
Please get in contact for more information and see the official announcement (no German necessary though):
stellen.angebote.uni-greifswald.de/jobposting/6...
Technische*r Assistent*in oder Laborant*in - Institut für Biochemie 25/M08
stellen.angebote.uni-greifswald.de
May 14, 2025 at 9:22 AM
We are hiring:
Technical/lab assistance; permanent position, up to salary grade E9a! Close to the Baltic Sea in a newly establishing group.
Please get in contact for more information and see the official announcement (no German necessary though):
stellen.angebote.uni-greifswald.de/jobposting/6...
Technical/lab assistance; permanent position, up to salary grade E9a! Close to the Baltic Sea in a newly establishing group.
Please get in contact for more information and see the official announcement (no German necessary though):
stellen.angebote.uni-greifswald.de/jobposting/6...
Reposted by Schlundt lab
Betriebswirtschaftslehre, Landschaftsökologie & Naturschutz oder ein Lehramtsstudium Deutsch? Um Studieninteressierten einen Einblick in das Studienangebot der Universität Greifswald zu geben, veranstaltet die Uni am 16. und 17. Mai 2025 Hochschulinfotage. Herzliche Einladung:
https://bit.ly/42GvaDk
https://bit.ly/42GvaDk
May 2, 2025 at 1:45 PM
Betriebswirtschaftslehre, Landschaftsökologie & Naturschutz oder ein Lehramtsstudium Deutsch? Um Studieninteressierten einen Einblick in das Studienangebot der Universität Greifswald zu geben, veranstaltet die Uni am 16. und 17. Mai 2025 Hochschulinfotage. Herzliche Einladung:
https://bit.ly/42GvaDk
https://bit.ly/42GvaDk
Reposted by Schlundt lab
Ein Forschungsteam untersuchte Todesfälle von DDR-Bürger*innen, die die risikovolle Flucht in den Westen wagten. Nun ist die Publikation „Tödliche Ostseefluchten aus der DDR 1961 – 1989.“ erschienen. Im Rahmen des Dies academicus hält das Team den Festvortrag.
https://ugreif.de/gbf97.qr
https://ugreif.de/gbf97.qr
April 30, 2025 at 12:35 PM
Ein Forschungsteam untersuchte Todesfälle von DDR-Bürger*innen, die die risikovolle Flucht in den Westen wagten. Nun ist die Publikation „Tödliche Ostseefluchten aus der DDR 1961 – 1989.“ erschienen. Im Rahmen des Dies academicus hält das Team den Festvortrag.
https://ugreif.de/gbf97.qr
https://ugreif.de/gbf97.qr
Reposted by Schlundt lab
This is from The Tonight Show with Johnny Carson aired on May 20th, 1977.
Carl Sagan says something very important, a strong message that didn't lose any validity since then.
Carl Sagan says something very important, a strong message that didn't lose any validity since then.
April 30, 2025 at 1:12 PM
This is from The Tonight Show with Johnny Carson aired on May 20th, 1977.
Carl Sagan says something very important, a strong message that didn't lose any validity since then.
Carl Sagan says something very important, a strong message that didn't lose any validity since then.
Reposted by Schlundt lab
Please join us for an exciting meeting on "Eukaryotic RNA turnover: from fundamentals to applications" in Brighton, UK this August! We have an exciting lineup of speakers, and will feature many selected talks. Abstract deadline is June 27! www.eventsforce.net/biochemsoc/f...
www.eventsforce.net
April 25, 2025 at 2:37 PM
Please join us for an exciting meeting on "Eukaryotic RNA turnover: from fundamentals to applications" in Brighton, UK this August! We have an exciting lineup of speakers, and will feature many selected talks. Abstract deadline is June 27! www.eventsforce.net/biochemsoc/f...
Congratulations Uwe! Clearly deserved!
🎓 Herzlichen Glückwunsch, Prof. Dr. Dr. Uwe Bornscheuer!
Am 11. April 2025 wurde Uwe Bornscheuer für seine wegweisenden Forschungsarbeiten im Bereich Biokatalyse die Ehrendoktorwürde der Königlichen Technischen Hochschule (KTH) Stockholm verliehen. Weitere Informationen: https://ugreif.de/htp74
Am 11. April 2025 wurde Uwe Bornscheuer für seine wegweisenden Forschungsarbeiten im Bereich Biokatalyse die Ehrendoktorwürde der Königlichen Technischen Hochschule (KTH) Stockholm verliehen. Weitere Informationen: https://ugreif.de/htp74
April 14, 2025 at 10:47 AM
Congratulations Uwe! Clearly deserved!
Proud to post our first new publication on bsky!
Greatful for the very straightforward collaboratoin with the Rief lab in Munich: This is what we did together with them:
www.pnas.org/doi/10.1073/...
Congrats to everyone, especially Jan-Niklas and Andreas!
Greatful for the very straightforward collaboratoin with the Rief lab in Munich: This is what we did together with them:
www.pnas.org/doi/10.1073/...
Congrats to everyone, especially Jan-Niklas and Andreas!
Roquin exhibits opposing effects on RNA stem-loop stability through its two ROQ domain binding sites | PNAS
The interaction of mRNA and regulatory proteins is critical for posttranscriptional
control. For proper function, these interactions, as well as th...
www.pnas.org
April 9, 2025 at 7:15 PM
Proud to post our first new publication on bsky!
Greatful for the very straightforward collaboratoin with the Rief lab in Munich: This is what we did together with them:
www.pnas.org/doi/10.1073/...
Congrats to everyone, especially Jan-Niklas and Andreas!
Greatful for the very straightforward collaboratoin with the Rief lab in Munich: This is what we did together with them:
www.pnas.org/doi/10.1073/...
Congrats to everyone, especially Jan-Niklas and Andreas!
Reposted by Schlundt lab
Die COVID-19-Pandemie hat gezeigt, wie eng Mensch, Tier, Umwelt und Gesellschaft miteinander verknüpft sind. Das hat dem Thema One Health große Aufmerksamkeit verschafft. Das Historische Institut der UG startet daher am 8.4. eine One-Health-Vortragsreihe: https://ugreif.de/tpuqk
April 3, 2025 at 5:00 PM
Die COVID-19-Pandemie hat gezeigt, wie eng Mensch, Tier, Umwelt und Gesellschaft miteinander verknüpft sind. Das hat dem Thema One Health große Aufmerksamkeit verschafft. Das Historische Institut der UG startet daher am 8.4. eine One-Health-Vortragsreihe: https://ugreif.de/tpuqk