Laura Mike
@lauraamike.bsky.social
1K followers 250 following 21 posts
Mike Lab @ Pitt-ID www.themikelab.com Studying how Kleb regulates capsule properties and causes infection #klebclub | #newPI
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Reposted by Laura Mike
tlowepower.bsky.social
Please repost -- The Univ. California Davis dept of Plant Pathology is hiring a Fungal biologist / Mycologist

Applications due Dec 1

Application portal: recruit.ucdavis.edu/JPF07339

Screenshot shows part of the job posting (with alt-text of the same text)
he Department of Plant Pathology at the University of California, Davis is seeking applications for a fulltime, tenure-track Assistant Professor position in Mycology, with a focus on plant pathogenic, symbiotic, 
or mycotoxigenic fungi and fungal-like organisms (e.g., oomycetes). We are looking for a highly 
motivated and creative scientist with a strong background in mycology and/or the biology of fungi and 
fungal-like organisms that interact with plants. The successful candidate will be expected to develop a 
world-class, externally funded research program that integrates both fundamental and applied aspects 
of fungal biology within the context of plant pathology. We welcome applicants pursuing a wide range 
of research topics related to plant-associated fungi, including but not limited to mechanisms of fungal 
pathogenesis or symbiosis with plants, population genomics and evolution of fungal plant pathogens, 
plant-associated fungal microbiomes and plant-microbe interactions, and/or one health approaches to 
fungal diseases and antifungal resistance. Applicants working in other relevant research areas involving 
pathogenic, symbiotic, or mycotoxigenic fungi or fungal-like organisms that affect plant health are also 
encouraged to apply. The successful candidate will have significant opportunities for collaboration with 
faculty in plant pathology, microbiology, genomics, and agricultural sciences, and to contribute to 
addressing issues of importance to California’s agricultural and natural ecosystems.
The appointee primary teaching responsibilities will be teaching Introductory Mycology, an upperdivision lab class, and SAS 30, Mushroom, Molds & Society, a general education class for non-majors. 
Additional graduate and undergraduate teaching responsibilities may be assigned based on 
departmental needs and the candidate’s expertise. The department offers modern instructional 
facilities, including a newly renovated teaching laboratory.
Reposted by Laura Mike
olayarendueles.bsky.social
Check out @julielebris.bsky.social’s thread on our latest manuscript describing phenotypic heterogeneity in capsule production in Klebsiella & Acinetobacter @klebclub.bsky.social

This work started when I was still in @pasteur.fr & got finished in @cbitoulouse.bsky.social
#microsky #phagesky
Reposted by Laura Mike
globaluti.bsky.social
Daisy is a healthy pup, but she's still pawsitively devoted to supporting animals' urinary health ❤️🐶

That's why our #UTIhour on October 14th (12EDT) is on veterinary #UTI!

Do you have a furry friend who supports urinary health? Post a photo and tag us or send it here to post
A white dog curled up on a fluffy black bed with her ball
Reposted by Laura Mike
proteusqueen.bsky.social
New publication from our lab, featuring Dr. Santosh Paudel’s work offers a refined cost-effective approach to study bacterial growth rates during infection @globaluti.bsky.social #UTIsky
Reposted by Laura Mike
tlowepower.bsky.social
Microbiology professor, want to join a slack for microbiology professors, any career stage, diverse career types (pure teaching, med school, R1, community college, pure research fed PIs, ...)

Message me for an invite link if you are interested.

No imposter syndrome, if you are 1% micro, join!
Reposted by Laura Mike
laurenpalmer.bsky.social
Congratulations to 2025 GRC Microbial Adhesion and Signal Transduction Poster Award Winners!! 🎆🥂🙌 Thank you @cp-cell.bsky.social and @femsmicro.org for sponsoring!

From,
Your secret judges 🤫
Michael Patnode with Rachel Washburn, Jessica Aycock, and Mason Clark, winners of GRC MAST poster awards from Cell Press and FEMS
Reposted by Laura Mike
kampmann.bsky.social
Tenure-track faculty search of the UCSF Biochemistry & Biophysics Department is open for applications!

We are looking for creative, innovative scientists asking fundamental questions in any area of biology.

Join our vibrant, collaborative, and supportive community!

aprecruit.ucsf.edu/JPF05702
Reposted by Laura Mike
abaumler.bsky.social
Infection and Immunity is now welcoming nominations for highly promising scientists at the assistant professor level (or equivalent) to submit research to the next New Voices in Microbiology Collection!

Please nominate by the August 18 deadline using the below link:
app.asm.org/account/logi...
lauraamike.bsky.social
It's seem like arginine is emerging as a major host cue. So we wrote an IAI minireview on how arginine levels vary between host tissues and affect microbial behavior.

The review is online today!
journals.asm.org/doi/epdf/10....

@brookeeryan3.bsky.social

#microsky
Known effects of arginine on Gram-positive and Gram-negative behavior
lauraamike.bsky.social
I think about you often - we should do an e-coffee some time!
lauraamike.bsky.social
Looking forward to reading! The link isn't working for me (not sure if it's my computer) but you may want to check it. I could access it here: journals.asm.org/doi/10.1128/...
lauraamike.bsky.social
5/ We identified a highly conserved (99.9%) ARG box in the rmp promoter. Mutating the ARG box eliminates ArgR binding to the rmp promoter and results is loss of hvKp mucoidy. We validated that arginine- and ARG box-dependent control of mucoidy occurs in 4 other hvKp isolates.
lauraamike.bsky.social
4/ Loss of ArgR reduces bacterial adherence to macrophages and decreases fitness in a murine pneumonia model. Notably, there are high levels of arginine in lung tissue. Also, human serum has higher levels of arginine than urine and we observe higher mucoidy in serum, which requires ArgR.
lauraamike.bsky.social
3/ The ArgR transcriptional regulator responds to arginine and positively regulates the rmp locus (regulator of mucoid phenotype). This induces the longer, more uniform capsular polysaccharides responsible for the mucoid phenotype.
lauraamike.bsky.social
2/ We used defined media with individual amino acids absent to identify that arginine is required for hvKp mucoidy. Arginine was the only amino acid sufficient to stimulate mucoidy.
lauraamike.bsky.social
Our paper reporting a highly conserved mechanism by which arginine positively regulates hypervirulent K. pneumoniae mucoid phenotype is now fully online.
rdcu.be/euiWG

Summary picture is below, but details in the 🧵
Overview of paper revealing role of arginine in regulating K. pneumoniae mucoidy.
Reposted by Laura Mike
vscooper.micropopbio.org
Welcome to all attending @asm.org #Microbe2025 and to all following here. Looking forward to a great meeting!

Delighted that many labmates & colleagues are presenting, as follows, and to celebrate the publication of the Academy's Early Microbial Life report, which I co-chaired.

Check these out!🧵
lauraamike.bsky.social
📣Introducing Dr. @brookeeryan3.bsky.social! First Mike Lab defense and Brooke knocked it out of the park, can't wait to share her work soon.

Congratulations! 🥂
Reposted by Laura Mike
zeynepbaharoglu.bsky.social
Marie Curie fellowship, post-doc hosting oppotunity in my lab. MSCA Post-doctoral Fellowship at IBPC Paris on RNA modifications in bacteria (FRANCE) 🦠💫 euraxess.ec.europa.eu/jobs/hosting...
euraxess.ec.europa.eu
Reposted by Laura Mike
kelwyres.bsky.social
Working on #klebsiella genomes? ✅
Want to collaborate globally to advance Klebs genomic epi? ✅

Please join us via the KlebNET-GSP Epidemiology consortium ⬇️

#microsky #AMR
klebnet.bsky.social
We are pleased to launch the KlebNET Genomic Epidemiology Consortium!

We aim to build a public metadata repository; systematic risk framework for global genomic surveillance; and genomic epi reviews for high-impact #Klebsiella clones.

Join us here:
klebnet.org/klebnet-gsp-...

#ABPHM25
KlebNET-GSP
klebnet.org