Rory Hennell James
@rorydhj.bsky.social
530 followers 830 following 49 posts
Postdoc at the CSSB Hamburg, studying mycobacterial secretion with #CryoEM and #CryoET. Generally something of a nerd. He/him.
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Reposted by Rory Hennell James
beijingpalmer.bsky.social
Explaining to my wife that I cannot simply “read the books I’ve already bought and haven’t read” like some kind of peasant.
Reposted by Rory Hennell James
tobiaswarnecke.bsky.social
Become my colleague @oxfordbiochemistry.bsky.social !
2 Associate Professorships in the areas of
- prokaryotic/eukaryotic microbiology
- metabolism

my.corehr.com/pls/uoxrecru...
Job Details
my.corehr.com
Reposted by Rory Hennell James
biozentrum.unibas.ch
Assistant/Associate Professor in Structural Biology, Biophysics or Biological Imaging

www.biozentrum.unibas.ch/open-positio...

#biozentrum #University #Basel #Professor #Structural #Biology #Biophysics #Biological #Imaging
Reposted by Rory Hennell James
adamrutherford.bsky.social
Phenomenal. In my 10 year update of A Brief History, I make the point that in the first edition, not one disease had been successfully treated using gene therapy. Today that number is at least 7.
Reposted by Rory Hennell James
wilbertbitter.bsky.social
PPE51 is one of the best candidates to form a MOM transport channel. However, our data indicate that it is not that simple. PPE51 mutations in Mmarinum (4 close homologs) indeed reduce the growth on glycerol & glucose, but also highly increase permeability.. and no, we do not fully understand this
PPE51 modulates membrane integrity in Mycobacterium marinum | mBio
The impermeable outer membrane of pathogenic mycobacteria presents a major obstacle to nutrient acquisition and antibiotic penetration. PPE51, a substrate of the ESX-5 secretion system, has previously...
journals.asm.org
Reposted by Rory Hennell James
biorxiv-biochem.bsky.social
Structure and substrate recognition by the Twin-arginine translocation (Tat) pathway core complex https://www.biorxiv.org/content/10.1101/2025.09.18.677151v1
Reposted by Rory Hennell James
rorydhj.bsky.social
I've recently switched to Sumatra PDF for this reason, but I haven't found a decent free reader for android on my phone/tablet
Reposted by Rory Hennell James
samuelhking.bsky.social
Many of the most complex and useful functions in biology emerge at the scale of whole genomes.

Today, we share our preprint “Generative design of novel bacteriophages with genome language models”, where we validate the first, functional AI-generated genomes 🧵
rorydhj.bsky.social
Is anyone in #MicroSky aware of the rapamycin dimerisation working in (myco)bacteria? Or some other inducible dimerisation?

I'd like to give this a go but I'm wary of fusing a 24-mer to my protein of interest
rorydhj.bsky.social
Printing files from Nemo Andrea here:https://www.printables.com/model/310139-transmission-electron-microscope
rorydhj.bsky.social
Pretty pleased with my 3d-printed Jeol 1400. But does anyone in #TeamTomo or #cryoEM have a 3D model or technical drawings of a Krios/Aquilos/Arctis I could have a go at printing?
A 3D printed model of a Jeol 1400 transmission electron microscope. The microscope is a column of white plastic on a black base with black and gold accents. A 3D printed model of a Jeol 1400 transmission electron microscope. The microscope is a column of white plastic on a black base with black and gold accents. It has been opened to show gold electron lenses in cutaway view.
rorydhj.bsky.social
But have you tried a Franzbrötchen?
rorydhj.bsky.social
This looks super cool, and could be the solution to a problem I've been having for a while.

Congrats all!
tbharat-lab.bsky.social
Sub-cellular chemical mapping in bacteria using correlated cryogenic electron and mass spectrometry imaging

Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social

www.biorxiv.org/cgi/content/...
@mrclmb.bsky.social @wellcometrust.bsky.social
rorydhj.bsky.social
I just got back from a wedding where this was a major topic of conversation. One friend put his back out turning to listen to the speeches.
rorydhj.bsky.social
I knew a kiwi student who saw "made with real fruit juice" on the label and thought it would be perfect for screwdrivers.

Apparently it still went down better than Stella at the graduate LGBTQ+ mixer
Reposted by Rory Hennell James
rorydhj.bsky.social
This was a brilliant course last year; I highly recommend it to anyone looking to improve their CryoFIB and CryoET skills!
mpibp.bsky.social
We’re hosting the @embo.org Practical Course on In-situ structural biology by CryoFIB and CryoET in April 2026! 🧬❄️ You can expect hands-on training, cutting-edge methods, and a chance to work alongside leading experts in structural biology. 🔗 Apply by Dec 8, 2025: meetings.embo.org/event/26-in-...
Reposted by Rory Hennell James
greening.bsky.social
1/3 Electricity from air! In the top journal Nano Energy today, we report the first fuel cell that makes power from air alone. We achieved this by using the enzyme Huc to oxidize ambient hydrogen. This results in a continuous low-level power from air and higher outputs with industrial waste gases.
Nanoengineered bioanode with oxygen-insensitive hydrogenase for sustainable energy harvesting from atmospheric hydrogen and waste gases
Enzymatic biofuel cells (EBFCs) utilizing hydrogenases to oxidize hydrogen offer a sustainable approach to energy conservation. However, the oxygen se…
www.sciencedirect.com
rorydhj.bsky.social
Congratulations @emfurlong.bsky.social !
scienceanu.bsky.social
Three remarkable early-career researchers from ANU, Dr Emily Furlong, Dr Ashley Jones and Associate Professor Xiaolin Wang, have been recognised with prestigious ACT Young Tall Poppy Science Awards for their significant contributions to science. Congratulations!
science.anu.edu.au/news-events/...
Young science scholars flourish as tall poppies
Three early-career ANU academics have been honoured with ACT Young Tall Poppy Science Awards.
science.anu.edu.au
rorydhj.bsky.social
That means it's 10 years since I did my summer project at @diamondlightsource.bsky.social. How time flies!
walshdls.bsky.social
krios 1 @diamondlightsource.bsky.social celebrated 10 years of user operations last week - many people thought we were mad to plonk it down in this spot in the synchrotron …but its still there as we ended up with a lot more in a very small space of time !
Titan krios I (a 300 KeV Cryo transmission electron microscope) with its 10 yr birthday hat in the experimental hall of Diamond Light Source.
Reposted by Rory Hennell James
debnathghosal.bsky.social
📣 New paper alert! Just out in Cell Reports! pubmed.ncbi.nlm.nih.gov/40644298/
Thrilled to share that we have discovered a brand-new anti-phage defense system! Bacteria have evolved various defense strategies (CRISPR etc) to counter phage attacks. We found a new one - fascinating and dramatic
⚔️🦠❄️🔬
Reposted by Rory Hennell James
cryonas.bsky.social
ASS is short for acephalic spermatozoa syndrome in which head and tail of sperm are detached⛓️‍💥, commonly caused by mutations in the gene encoding for SUN5. Using in situ cryo-ET❄️🔬 we find that SUN5 forms a protein lattice in the nuclear envelope (NE) at the head-tail junction of mammalian sperm.1/4
rorydhj.bsky.social
I am only listening because you won an award. Or at least I started listening after I saw your acceptance speech...