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Lauren Howson

@lauren-j-howson.bsky.social

1.5K followers 550 following 29 posts

WEHI Senior Research Officer @wehi-research.bsky.social Interested in unconventional T cells and immune disorders #immunology #immunosky @ox.ac.uk University of Oxford DPhil | @utas.edu.au University of Tasmania BMedRes

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Lauren Howson @lauren-j-howson.bsky.social · Apr 15

🚨 New publication alert! 🚨
Thrilled to share our latest research out today in @jclinical-invest.bsky.social! This work is another great outcome of my amazing clinical research partnership with first author Samantha Chan and RMH. @wehi-research.bsky.social #immunology #research #JCI

JCI - A dominant-negative IFNGR1 variant reveals broad immune cell sequestering of IFN-γ

www.jci.org

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Reposted by Lauren Howson

Sophia Davidson @sciencesophie.bsky.social · 2d

Dear Everyone, I've read the #NHMRC draft strategy and I have notes ...

So I'm going to...🧵🤔🧵😱🧵😵‍💫🧵🙏🧵🧵🧵
This is a repost from X because you all need to know!

#NHMRCdraftStratergy #Ihavenotes #ValueFundamentalScience

@nhmrc.bsky.social

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Reposted by Lauren Howson

WEHI (The Walter and Eliza Hall Institute of Medical Research) @wehi-research.bsky.social · 15d

WEHI scientists led by @groomlab.bsky.social‬ @chinweetan.bsky.social map how Tfh cells tailor instructions based on infection type. A step toward smarter vaccines and therapies.

📄 In @natimmunol.nature.com: www.nature.com/articles/s41...

🔗 Read more: www.wehi.edu.au/news/unlocki...

Yellow Tfh cells activate magenta B cells to produce protective antibodies during parasite infection.

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Reposted by Lauren Howson

WEHI (The Walter and Eliza Hall Institute of Medical Research) @wehi-research.bsky.social · 22d

Big news! The Snow Centre for Immune Health welcomes our new Director, globally renowned coeliac research leader, Associate Professor Jason Tye-Din.

Learn more: www.wehi.edu.au/news/new-dir...

#ImmuneHealth #MedicalResearch #Leadership #SnowCentre #WEHI #RMH

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Lauren Howson @lauren-j-howson.bsky.social · 27d

Congratulations Jo, Len, Chin Wee and team - beautiful work!!

Reposted by Lauren Howson

Joanna Groom @groomlab.bsky.social · 27d

Thrilled to have our latest research @wehi-research.bsky.social published in @natimmunol.nature.com
www.nature.com/articles/s41...

This work was an outstanding partnership between talented PhD student Len Dalit (now postdoc, no 🦋) and bioinformatician @chinweetan.bsky.social

Thread below...

Divergent cytokine and transcriptional signatures control functional T follicular helper cell heterogeneity - Nature Immunology

Dalit, Tan and colleagues provide a multiomic profile of T follicular helper (TFH) cells responses to diverse pathogens, revealing a blueprint for transcriptional flexibility and new tools to interrog...

www.nature.com

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Reposted by Lauren Howson

Edelblum Lab @edelblumlab.bsky.social · Aug 28

👀 We're on the lookout for a talented immunologist to join us for a postdoc at Mount Sinai! If you are a recent PhD graduate, love spectral flow and want to join our γδ T cell crew, apply below! Livable wage + subsidized housing + Central Park. Help us spread the word! #gdTcells #Immunosky #GISky

Post Doctoral Fellow-MSH-20093-003 in New York, NY | Mount Sinai Health Systems

Mount Sinai is hiring a Post Doctoral Fellow-MSH-20093-003 in New York, NY. Review all of the job details and apply today!

careers.mountsinai.org

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Reposted by Lauren Howson

Australian Museum Eureka Prizes @eurekaprizes.bsky.social · Jul 31

PINK1 Parkinson's Disease Research Team @wehi-research.bsky.social is a finalist in the @unsw.edu.au Eureka Prize for Scientific Research.

Learn more: youtu.be/senXARXzO20

#EurekaPrizes @komanderlab.bsky.social @zhongyangan.bsky.social @sylviecallegari.bsky.social @nskirk.bsky.social

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Lauren Howson @lauren-j-howson.bsky.social · Jul 31

Congratulations and very well deserved @trubianojason.bsky.social!! 👏👏👏

Australian Museum Eureka Prizes @eurekaprizes.bsky.social · Jul 31

Professor @trubianojason.bsky.social is a finalist in the Eureka Prize for Emerging Leader in Science.

Learn more: youtu.be/qaPw-YsXix4

#EurekaPrizes

Lauren Howson @lauren-j-howson.bsky.social · Jul 28

Thanks Danika!!

Lauren Howson @lauren-j-howson.bsky.social · Jul 28

Was a pleasure to present at the ASI VIC/TAS Branch meeting last week, where I shared our most recently published work on two patients with IFN-γR1 deficiency! @wehi-research.bsky.social #IEI #immunosky
Photo credit @graslab.bsky.social

Lauren giving her presentation (standing at lectern with an overview slide on IFNgR1 deficiency)

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Reposted by Lauren Howson

Zach Walsh @zwalsh96.bsky.social · Jul 2

Thrilled to re-share our tweetorial on Bluesky: now out in @cp-cell.bsky.social (🔗 tinyurl.com/3a55tsky) - we present a framework to accelerate variant classification, diagnosis & treatment of inborn errors of immunity. A dream MD/PhD project, which has already led to the treatment of a patient.

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Lauren Howson @lauren-j-howson.bsky.social · Jul 3

Wow! Amazing work - truly bench to bedside all in one epic paper!! Congratulations 👏🏻👏🏻👏🏻

Reposted by Lauren Howson

WEHI (The Walter and Eliza Hall Institute of Medical Research) @wehi-research.bsky.social · Jun 9

A new blood test could revolutionise the way coeliac disease is diagnosed after detecting the condition in patients, even when they weren’t eating gluten.

Brilliant study led by Assoc Prof Jason Tye-Din and Olivia Moscatelli, now published in Gastroenterology.

www.wehi.edu.au/news/landmar...

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Reposted by Lauren Howson

Cyril Seillet, PhD @seilletlab.bsky.social · Jun 2

🎓 PhD positions available @MonashUni
Join our lab to explore how neurons and immune cells shape gut immunity!
🧬 Single-cell RNAseq
🔬 3D imaging
🧠 Neuro-immune interactions
👥 Great mentoring & collaborations

Apply now 👉 tinyurl.com/Seilletlab

Understanding the neuroimmune regulation of innate immunity | Supervisor Connect

tinyurl.com

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Reposted by Lauren Howson

Marnie Blewitt @marnieblewitt.bsky.social · Jun 4

Reposting - please consider applying for a lab head role @wehi-research.bsky.social in Australia. It is a wonderful place to work, in a great country and with lovely colleagues. Clearly I’m biased on all of those counts. Please repost and/or apply!

Marnie Blewitt @marnieblewitt.bsky.social · May 13

www.wehi.edu.au/careers/make...
WEHI is looking for new lab heads! New and experienced lab heads welcome. Check out the ad, consider applying and share. We’re a collaborative bunch, in Australia, with fabulous technology, great colleagues at a values-driven organisation. @wehi-research.bsky.social

Make your future Melbourne | WEHI

Lead the next wave of biomedical discovery

www.wehi.edu.au

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Lauren Howson @lauren-j-howson.bsky.social · May 31

Thanks Payal - and so sorry to have missed chatting with you (I was probably off chasing appetizer trays 🤭). It was truly my favourite conference, such a welcoming and and friendly community for newbies to the field like me. Very excited to attend them in the future, so I’ll see you in Poland!

Lauren Howson @lauren-j-howson.bsky.social · May 25

Congrats!! It was a beautiful talk 👏🏻👏🏻👏🏻

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Lauren Howson @lauren-j-howson.bsky.social · May 21

Had a fabulous time presenting on day 1 of the #gdtcell conference in Toronto! Was a fantastic poster session with lots of discussion and interest! @forum-gd.bsky.social

Lauren standing in front of her poster on γδ T cells in CVID.

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Reposted by Lauren Howson

Joanna Groom @groomlab.bsky.social · May 8

Excited to have our latest research published in @jem.org this week and also highlighted by @natrevimmunol.nature.com
@wehi-research.bsky.social @benjbroom.bsky.social

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Reposted by Lauren Howson

WEHI (The Walter and Eliza Hall Institute of Medical Research) @wehi-research.bsky.social · May 7

Future vaccines a step closer. Research from @groomlab.bsky.social, @benjbroom.bsky.social and team use novel approach and mRNA tech to boost stem cell-like memory CD8+ T cells after vaccination.

Published in @jem.org

www.wehi.edu.au/news/vaccine...

A visualisation of immune cells, with headline "Long-lasting vaccines of the future a step closer"

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Reposted by Lauren Howson

Journal of Clinical Investigation @jci.org · Apr 30

IFNGR1 gene errors cause susceptibility to mycobacterial disease.

@lauren-j-howson.bsky.social & team @wehi-research.bsky.social describe an autosomal dominant IFNGR1 variant that reveals the ubiquitous nature of IFNγR1 expression & its ability to sequester IFNγ on cell surface: buff.ly/5eqJ2yR

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Reposted by Lauren Howson

jazziie.bsky.social @jazziie.bsky.social · Apr 17

What a way to start the Easter break! Congrats Samantha Chan and @lauren-j-howson.bsky.social on this wonderful publication. Look forward to more amazing discoveries from both of you and the team!

Lauren Howson @lauren-j-howson.bsky.social · Apr 15

JCI - A dominant-negative IFNGR1 variant reveals broad immune cell sequestering of IFN-γ

www.jci.org

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Lauren Howson @lauren-j-howson.bsky.social · Apr 17

Thanks Jaz!!! 😄

Lauren Howson @lauren-j-howson.bsky.social · Apr 15

Thanks to all the coauthors including the clinical team at Royal Melbourne Hospital for your contribution to this work.

Lauren Howson @lauren-j-howson.bsky.social · Apr 15

We found that patients with dominant negative IFN-γ deficiency show prolonged cell surface retention of IFN-γ bound to the truncated IFN-γ receptor. This broad sequestering of IFN-γ has the potential to reduce systemic IFN-γ bioavailability in affected patients.