Check out our new preprint on an integrated pipeline combining in situ #cryo-ET with MALDI #MSImaging for single-cell identification and classification from previously analysed EM-grids. Link: www.biorxiv.org/content/10.1...
Really proud of our most recently published work 😊 another installment in the story of the most incredible protein out there: the TOM complex 💜 #powerhouseofthecell Thanks @ahmed-noor-agip.bsky.social for the legendary team work and @lea-dietrich.bsky.social for all the support 💕 #teamCRYO
🔬 Check out our new article on the mitochondrial TOM complex! Researchers from the Structural Biology Department have resolved a high-resolution structure of the main entry point for proteins into mitochondria. 🚪 🤩 Read more: www.biophys.mpg.de/2876415/tom-main-gate-into-mitochondria?c=2011019
I'm still amazed to see this! Big thank you to Werner Kühlbrandt, Martin Beck and @erin-schuman.bsky.social for all their support and mentorship! I can't wait to get started on the exciting research projects at the @mpibrain.bsky.social ! 🧬🧠❄️🔬
Big congratulations to Dr. Lea Dietrich @lea-dietrich.bsky.social for receiving the Otto Hahn Medal from the @maxplanck.de for her research on mitochondrial architecture! 🏅 A brilliant young scientist and a great role model 💪
After 5 amazing years @pilhoferlab.bsky.social I'm starting my lab @embl.org Grenoble this November embl.org/wollweber We'll image Asgard archaea and many other strange microbes ( #archaeasky, #protistsonsky..) to understand eukaryogenesis First job ad: #teamtomo scientist!🔬❄️ tinyurl.com/2rdu2ze6
Please enjoy our (@pamornelas.bsky.social and I) work on the cryoEM structures of TOM from Chaetomium thermophilum, revealing insights into the early stages of preprotein translocation. The paper is still under review, so fingers crossed 🤞. www.biorxiv.org/content/10.1...@mpibp.bsky.social
Happy at the finish line of the Leipzig Marathon! Many thanks to @andschwarz.bsky.social , the people of leipzig and my mitochondria. Couldn't have done it without you! What a blast! ☺️🏃🏻♀️💨🏅 Many thanks to @pamornelas.bsky.social for the ATP synthase print! 🩵
Thrilled to share the structure of dimerised human PINK1 docked to an endogenous translocase array on the mitochondrial surface, composed of two TOM complexes, bridged by a VDAC2 dimer! Published today in Science www.science.org/doi/10.1126/...
Excited to share our new preprint "Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons" www.biorxiv.org/content/10.1...
We combine optogenetic stimulation of neurons with in situ cryo-ET to characterize membrane dynamics during synaptic vesicle fusion ❄️🔬⏱️
