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Reposted by Leiden Early Drug Discovery & Development (LED3)

Stephan Hacker @stephanhacker2.bsky.social · 13h

Very much looking forward to hosting Nicolas Winssinger for a @led3hub.bsky.social Lecture on October 30th.

If you are interested in nucleic acid-encoded libraries, mark your calendars and join us in Leiden @leidenscience.bsky.social.

www.universiteitleiden.nl/en/science/l...

#ChemBio #ChemSky

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Leiden Early Drug Discovery & Development (LED3) @led3hub.bsky.social · 1d

We are very happy that Tudor Oprea from Expert Systems Inc. visited us today for a talk. He talked about the use of Machine Learning and Artificial Intelligence in Drug Discovery.

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Reposted by Leiden Early Drug Discovery & Development (LED3)

Stephan Hacker @stephanhacker2.bsky.social · 1d

Great talk by Tudor Oprea of Expert Systems Inc. today at the @led3hub.bsky.social. He talked about the potential of #ArtificialIntelligence and #MachineLearning in #DrugDiscovery. (1/5)

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Reposted by Leiden Early Drug Discovery & Development (LED3)

Stephan Hacker @stephanhacker2.bsky.social · 1d

Are you interested in the use of nucleic acid-encoded libraries in #DrugDiscovery?

Join us for the @led3hub.bsky.social Lecture by Nicolas Winssinger on October 30th in Leiden.

#ChemSky #ChemBio

Leiden Early Drug Discovery & Development (LED3) @led3hub.bsky.social · 1d

We are very much looking forward to the LED3 Lecture by Nicolas Winssinger on Thursday, October 30th, at 4 p.m.

He will talk about his research into "Programing responsive assemblies from PNA-encoded and folded peptides"

www.universiteitleiden.nl/en/science/l...

#ChemSky #ChemBio #DrugDiscovery

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Leiden Early Drug Discovery & Development (LED3) @led3hub.bsky.social · 1d

We are very much looking forward to the LED3 Lecture by Nicolas Winssinger on Thursday, October 30th, at 4 p.m.

He will talk about his research into "Programing responsive assemblies from PNA-encoded and folded peptides"

www.universiteitleiden.nl/en/science/l...

#ChemSky #ChemBio #DrugDiscovery

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Reposted by Leiden Early Drug Discovery & Development (LED3)

Madeline Kavanagh @mads-chem.bsky.social · 7d

Awesome talk from @ox.ac.uk Prof. Alex Bullock @leidenscience.bsky.social today. Neat examples of #neomorphic gain-of-function mutations driving disease by acting as #molecularglues and using #FBDD to expand the #druggability of E3ligases with thesgc.bsky.social‬
an#EUbOPENEN @led3hub.bsky.social

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Reposted by Leiden Early Drug Discovery & Development (LED3)

Stephan Hacker @stephanhacker2.bsky.social · 7d

Inspiring talk by Alex Bullock from @ox.ac.uk today at @leidenscience.bsky.social. He talked about his group's research into targeting proteins with mutations that cause neomorphic functions with inhibitors and degraders. www.nature.com/articles/s41...
#ChemBio #ChemSky #DrugDiscovery #TPD

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Leiden Early Drug Discovery & Development (LED3) @led3hub.bsky.social · 7d

We are very happy that Alex Bullock from the University of Oxford (@ox.ac.uk) visited us today for a very well attended lecture. He talked about his group's work on making new E3 ligases available for degrader development using PROTACs and molecular glues. www.nature.com/articles/s41...

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Leiden Early Drug Discovery & Development (LED3) @led3hub.bsky.social · 13d

We were very excited that Willem Velema visited us today for a great LED3hub Lecture. He talked about his group's diverse research projects on better understanding the structure of RNA motives and their ligandability with small molecules using techniques such as affinity-based profiling.

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Reposted by Leiden Early Drug Discovery & Development (LED3)

Stephan Hacker @stephanhacker2.bsky.social · 13d

Insightful @led3hub.bsky.social Lecture today by Willem Velema. He talked about his group's projects to better understand the structure of bacterial RNAs and to make them amenable to #antibiotic drug discovery. (1/7) pubs.acs.org/doi/10.1021/...
#ChemSky #ChemBio #DrugDiscovery

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Leiden Early Drug Discovery & Development (LED3) @led3hub.bsky.social · 14d

Do not miss this week's LED3 Lecture by Willem Velema!
www.universiteitleiden.nl/en/science/l...

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Leiden Early Drug Discovery & Development (LED3) @led3hub.bsky.social · 14d

On October 14th, Kim Bonger (@kimmb1.bsky.social) will present her exciting research in our LED3hub at the @leidenscience.bsky.social Tuesday Talks to the Faculty.

If you are interested, make sure to register: www.universiteitleiden.nl/en/events/20...

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Reposted by Leiden Early Drug Discovery & Development (LED3)

Stephan Hacker @stephanhacker2.bsky.social · 17d

Looking forward to a great @led3hub.bsky.social Lecture by Willem Velema on Thursday. Excited to learn, how his group is targeting RNA to develop novel #antibiotics.

#ChemSky #ChemBio @leidenscience.bsky.social

Leiden Early Drug Discovery & Development (LED3) @led3hub.bsky.social · 17d

We are very much looking forward to the first LED3 Lecture of the academic year on Thursday, September 25th, at 4 p.m.

Willem Velema will talk about his research into targeting bacterial #RNA for #antibiotic development.

www.universiteitleiden.nl/en/science/l...

#ChemSky #ChemBio #DrugDiscovery

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Leiden Early Drug Discovery & Development (LED3) @led3hub.bsky.social · 17d

We are very much looking forward to the first LED3 Lecture of the academic year on Thursday, September 25th, at 4 p.m.

Willem Velema will talk about his research into targeting bacterial #RNA for #antibiotic development.

www.universiteitleiden.nl/en/science/l...

#ChemSky #ChemBio #DrugDiscovery

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Leiden Early Drug Discovery & Development (LED3) @led3hub.bsky.social · 19d

Exciting opportunity to join our LED3hub as a #PhD researcher in the group of Kim Bonger (@kimmb1.bsky.social) and to work on cutting-edge Translational Chemical Immunology. If you have a background in #Chemistry or #ChemBio, consider applying!

www.universiteitleiden.nl/en/vacancies...

PhD position in Translational Chemical Immunology

The Department of Chemical Biology and Immunology (CBI) of the Leiden Institute of Chemistry is looking for a PhD-candidate to study autoantigen-specific cell therapies employing synthetic chimeric au...

www.universiteitleiden.nl

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Reposted by Leiden Early Drug Discovery & Development (LED3)

Albert Heck @hecklab.bsky.social · Sep 4

Great line-up

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Leiden Early Drug Discovery & Development (LED3) @led3hub.bsky.social · Sep 4

We are very much looking forward to the LED3 Lectures 2025/2026. Already mark your calendars!
lnkd.in/e2GEibqP

Our speakers are:
Willem Velema
Nicolas Winssinger
Lotte Bjerre Knudsen
Anne Osbourn
Christina Woo
Thomas Clairfeuille
Peng Chen
Jon Stokes
@madelonmaurice.bsky.social

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Reposted by Leiden Early Drug Discovery & Development (LED3)

Stephan Hacker @stephanhacker2.bsky.social · Sep 2

Our dean, Jasper Knoester, opens the Academic Year at @leidenscience.bsky.social of @unileiden.bsky.social.

Great to see him highlight the importance of the faculty priority themes including that of Drug Discovery and Developing of our @led3hub.bsky.social. www.universiteitleiden.nl/en/science/l...

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Reposted by Leiden Early Drug Discovery & Development (LED3)

Stephan Hacker @stephanhacker2.bsky.social · Aug 28

Great talk by Guy Ron at the #MCBIM mini-symposium at @leidenscience.bsky.social.

He talked about multiplexed, single-molecule methods to detect #epigenetic modifications that are important in #cancer and can be used for #diagnosis.

www.nature.com/articles/s41...

#ChemSky #ChemBio #DrugDiscovery

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Reposted by Leiden Early Drug Discovery & Development (LED3)

Stephan Hacker @stephanhacker2.bsky.social · Aug 28

Interesting talk by Petra Heffeter at the #MCBIM mini-symposium at @leidenscience.bsky.social.

She talked about hypoxia-activated and albumin-bound, inorganic #prodrugs against #cancer.

www.sciencedirect.com/science/arti...
#ChemSky #ChemBio #DrugDiscovery

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Leiden Early Drug Discovery & Development (LED3) @led3hub.bsky.social · Aug 28

A great mini symposium on #cancer research today at @leidenscience.bsky.social organized by the #MCBIM department of Sylvestre Bonnet.

Petra Heffeter and Guy Ron talked about diverse aspects of cancer #diagnosis and #treatment.

#ChemSky #ChemBio #DrugDiscovery

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Leiden Early Drug Discovery & Development (LED3) @led3hub.bsky.social · Aug 28

We look forward to the LED3 Lecture by @madelonmaurice.bsky.social on June 25th, 2026. She will talk about her group's research on understanding patient-specific disease mechanisms to develop improved cancer-targeting strategies.

Already mark your calendars! www.universiteitleid...

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Reposted by Leiden Early Drug Discovery & Development (LED3)

Stephan Hacker @stephanhacker2.bsky.social · Aug 23

Very excited that Jon Stokes will visit us for a @led3hub.bsky.social Lecture. Curious to learn about the use of #ArtificialIntelligence in #antibiotics discovery.

www.universiteitleiden.nl/en/science/l...
#ChemBio #ChemSky @leidenscience.bsky.social

Leiden Early Drug Discovery & Development (LED3) @led3hub.bsky.social · Aug 21

We look forward to the LED3 Lecture by Jon Stokes on May 28th, 2026. He will talk about his group's exciting research into using #ArtificialIntelligence for drug discovery in the field of #antibiotics.

Already mark your calendars! www.universiteitleid...

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Reposted by Leiden Early Drug Discovery & Development (LED3)

Stephan Hacker @stephanhacker2.bsky.social · Aug 24

It was great to be able to present some of the newest work our group is doing at the @led3hub.bsky.social of @leidenscience.bsky.social to this expert audience and discuss scientific ideas. (2/3)

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Leiden Early Drug Discovery & Development (LED3) @led3hub.bsky.social · Aug 23

Exciting #PhD Opportunity in #DrugDiscovery at Leiden University!

The group of @mads-chem.bsky.social of the @led3hub.bsky.social is thrilled to announce a new PhD position at the intersection of #ChemicalBiology and #Immunology.

www.universiteitleiden.nl/en/vacancies...
#ChemBio #ChemSky

PhD Candidate in Chemical Biology and Immuno-metabolism

The Faculty of Science Leiden, the Leiden Institute of Chemistry and Leiden Institute of Biology are looking for a PhD candidate to pursue research on the development of drugs modulating immunometabolism. Immune dysregulation contributes to many human diseases, including cancer, cardiovascular…

www.universiteitleiden.nl

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