Leo Speidel
@leospeidel.bsky.social
210 followers
140 following
2 posts
Statistical and Population Genetics | RIKEN, iTHEMS (Japan) | 🇯🇵🇩🇪🇬🇧 |
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Arun Durvasula
@arundurvasula.bsky.social
· Jun 11
Not Just $N_e$ $N_e$-more: New Applications for SMC from Ecology to Phylogenies
Genomes contain the mutational footprint of an organism's evolutionary history, shaped by diverse forces including ecological factors, selective pressures, and life history traits. The sequentially Ma...
arxiv.org
Reposted by Leo Speidel
Reposted by Leo Speidel
Reposted by Leo Speidel
Lucy van Dorp
@lucyvandorp.bsky.social
· May 23
Ancient Borrelia genomes document the evolutionary history of louse-borne relapsing fever
Several bacterial pathogens have transitioned from tick-borne to louse-borne transmission, which often involves genome reduction and increasing virulence. However, the timing of such transitions remai...
www.science.org
Reposted by Leo Speidel
Reposted by Leo Speidel
Aylwyn Scally
@aylwyn-scally.bsky.social
· Mar 18
A structured coalescent model reveals deep ancestral structure shared by all modern humans - Nature Genetics
The cobraa model extends the pairwise sequentially Markovian coalescent to identify structured population history by examination of the model transition matrix. Applied to human polymorphism data, cob...
www.nature.com
Reposted by Leo Speidel
Aylwyn Scally
@aylwyn-scally.bsky.social
· Feb 21
Assistant/Associate Professor in Computational Biology - Job Opportunities - University of Cambridge
Assistant/Associate Professor in Computational Biology in the Department of Applied Mathematics and Theoretical Physics at the University of Cambridge.
www.jobs.cam.ac.uk
Reposted by Leo Speidel
Reposted by Leo Speidel
Kevin Daly
@gingerhowley.bsky.social
· Jan 30
Ancient genomics and the origin, dispersal, and development of domestic sheep
The origins and prehistory of domestic sheep (Ovis aries) are incompletely understood; to address this, we generated data from 118 ancient genomes spanning 12,000 years sampled from across Eurasia. Ge...
search.app
Reposted by Leo Speidel
Jonathan Pritchard
@jkpritch.bsky.social
· Jan 27
Jonathan Pritchard
@jkpritch.bsky.social
· Jan 26
Causal modeling of gene effects from regulators to programs to traits: integration of genetic associations and Perturb-seq
Genetic association studies provide a unique tool for identifying causal links from genes to human traits and diseases. However, it is challenging to determine the biological mechanisms underlying mos...
www.biorxiv.org
Reposted by Leo Speidel