Lews Caro
@lewsiferase.bsky.social
Evolution, biochemistry, and wherever that all takes me next!
HHMI-Jane Coffin Childs Fellow in Elde Lab, Utah.
Ph.D. U of Washington.
Son of immigrants 🇨🇴, he/him
HHMI-Jane Coffin Childs Fellow in Elde Lab, Utah.
Ph.D. U of Washington.
Son of immigrants 🇨🇴, he/him
Another selfish element in the best worm!
sept-1/zina-1 is an Ancient Toxin-Antidote System in Caenorhabditis elegans https://www.biorxiv.org/content/10.1101/2025.11.28.691152v1
December 6, 2025 at 12:43 PM
Another selfish element in the best worm!
Reposted by Lews Caro
Hello World! It took a minute, but much improved version (thank you peer review) of Joris paper is out
@genomebiolevol.bsky.social
bsky.app/profile/geno...
@genomebiolevol.bsky.social
bsky.app/profile/geno...
Mordier, @antoinemolaro.bsky.social et al. applied phylogenomic approaches to characterize the evolutionary trajectories and selective forces shaping mammalian Schlafen genes.
🔗 doi.org/10.1093/gbe/evaf172
#genome #evolution
🔗 doi.org/10.1093/gbe/evaf172
#genome #evolution
Recurrent Evolutionary Innovations in Rodent and Primate Schlafen Genes
Abstract. SCHLAFEN proteins are a large family of RNase-related enzymes carrying essential immune and developmental functions. Despite these important role
doi.org
October 6, 2025 at 11:54 AM
Hello World! It took a minute, but much improved version (thank you peer review) of Joris paper is out
@genomebiolevol.bsky.social
bsky.app/profile/geno...
@genomebiolevol.bsky.social
bsky.app/profile/geno...
Reposted by Lews Caro
The @uncchapelhill.bsky.social Department of Biology is searching for tenure-track Assistant Professor in Plant Molecular Biology. Chapel Hill is a wonderful place and Biology is an amazing group of people. To apply, see:
unc.peopleadmin.com/postings/307...
unc.peopleadmin.com/postings/307...
October 6, 2025 at 7:30 PM
The @uncchapelhill.bsky.social Department of Biology is searching for tenure-track Assistant Professor in Plant Molecular Biology. Chapel Hill is a wonderful place and Biology is an amazing group of people. To apply, see:
unc.peopleadmin.com/postings/307...
unc.peopleadmin.com/postings/307...
Reposted by Lews Caro
Check out this new Levine-Lampson collaboration, led by the talented Hyuk-Joon Jeon.
We explored the consequences of inheriting long telomeres from dad and short telomeres from mom. Or the reciprocal. Turns out, parent-of-origin matters (in mice, at least).
authors.elsevier.com/c/1loW-3QW8S...
We explored the consequences of inheriting long telomeres from dad and short telomeres from mom. Or the reciprocal. Turns out, parent-of-origin matters (in mice, at least).
authors.elsevier.com/c/1loW-3QW8S...
authors.elsevier.com
October 4, 2025 at 4:40 PM
Check out this new Levine-Lampson collaboration, led by the talented Hyuk-Joon Jeon.
We explored the consequences of inheriting long telomeres from dad and short telomeres from mom. Or the reciprocal. Turns out, parent-of-origin matters (in mice, at least).
authors.elsevier.com/c/1loW-3QW8S...
We explored the consequences of inheriting long telomeres from dad and short telomeres from mom. Or the reciprocal. Turns out, parent-of-origin matters (in mice, at least).
authors.elsevier.com/c/1loW-3QW8S...
Reposted by Lews Caro
Exciting news! I am launching the Lab of Polymicrobial Interaction & Evolution at IPMB at Academia Sinica (ipmb.sinica.edu.tw/en)! 🎉Our brand-new website is live: (www.labofpie.org). Check the lab of PIE out!!🥧🎈
IPMB | 中央研究院植物暨微生物學研究所
ipmb.sinica.edu.tw
July 10, 2025 at 7:19 PM
Exciting news! I am launching the Lab of Polymicrobial Interaction & Evolution at IPMB at Academia Sinica (ipmb.sinica.edu.tw/en)! 🎉Our brand-new website is live: (www.labofpie.org). Check the lab of PIE out!!🥧🎈
Reposted by Lews Caro
I’m thrilled to announce the launch of the Evolution of Chromosomes and Genomes (ECG) Lab at the Institute of Molecular Biology, Academia Sinica, Taiwan. Our lab website is now live—come check it out! sites.google.com/view/ecg-lab...
ECG LAB
"The only constant in life is change." — Heraclitus
Genetic conflicts — the good, the bad, and the ugly —
shape our lives over time
We aim to understand why even the most essential genes and chrom...
sites.google.com
July 11, 2025 at 8:23 PM
I’m thrilled to announce the launch of the Evolution of Chromosomes and Genomes (ECG) Lab at the Institute of Molecular Biology, Academia Sinica, Taiwan. Our lab website is now live—come check it out! sites.google.com/view/ecg-lab...
Absolutely stoked to be part of the JCC community! Let’s do some awesome science together!
We're thrilled to announce the 2025 class of Jane Coffin Childs Fellows!
See our latest blog post and "look book" to learn more about our newest Fellows and their exciting research!
www.jccfund.org/blog/the-jan...
www.jccfund.org/wp-content/u...
See our latest blog post and "look book" to learn more about our newest Fellows and their exciting research!
www.jccfund.org/blog/the-jan...
www.jccfund.org/wp-content/u...
www.jccfund.org
June 25, 2025 at 3:46 AM
Absolutely stoked to be part of the JCC community! Let’s do some awesome science together!
Reposted by Lews Caro
9 minutes. Hah. That's 8 mins too late in the worm community.
i am here to share what just happened. I just asked a fly colleague if they could share some reagents, and literally in 9 MINUTES they wrote back and said of course, we'll send everything and more.
this is reason #834 why the fly community is the best. THE BEST!!! 🪰💪
this is reason #834 why the fly community is the best. THE BEST!!! 🪰💪
May 30, 2025 at 1:41 AM
9 minutes. Hah. That's 8 mins too late in the worm community.
Reposted by Lews Caro
@lewsiferase.bsky.social fighting the good fight to put animal toxin-antidote elements on the map! Quite jazzed to see this story published. Tag yourself, I am the transient blob #teamTAs
#Celegans peel-1/zeel-1 is one of the best-characterized animal #toxin-antidote systems, but how does it work? @lewsiferase.bsky.social &co show that PEEL-1 co-opts the PMPL-1 to exert toxicity by creating a novel #IonChannel that leads to cell swelling @plosbiology.org 🧪 plos.io/3HfH8LN
May 28, 2025 at 5:36 PM
@lewsiferase.bsky.social fighting the good fight to put animal toxin-antidote elements on the map! Quite jazzed to see this story published. Tag yourself, I am the transient blob #teamTAs
Reposted by Lews Caro
#Celegans peel-1/zeel-1 is one of the best-characterized animal #toxin-antidote systems, but how does it work? @lewsiferase.bsky.social &co show that PEEL-1 co-opts the PMPL-1 to exert toxicity by creating a novel #IonChannel that leads to cell swelling @plosbiology.org 🧪 plos.io/3HfH8LN
May 27, 2025 at 11:41 PM
Reposted by Lews Caro
#Celegans peel-1/zeel-1 is one of the best-characterized animal #toxin-antidote systems, but how does it work? @lewsiferase.bsky.social &co show that PEEL-1 co-opts the PMPL-1 to exert toxicity by creating a novel #IonChannel that leads to cell swelling @plosbiology.org 🧪 plos.io/3HfH8LN
May 27, 2025 at 6:21 PM
#Celegans peel-1/zeel-1 is one of the best-characterized animal #toxin-antidote systems, but how does it work? @lewsiferase.bsky.social &co show that PEEL-1 co-opts the PMPL-1 to exert toxicity by creating a novel #IonChannel that leads to cell swelling @plosbiology.org 🧪 plos.io/3HfH8LN
Reposted by Lews Caro
Sometimes a paper stops you in your tracks.
New work from Loppin’s group found that histone eviction during sperm development ensures that paternal chromosomes aren’t mistaken for maternal chromosomes in the Drosophila embryo.
My Perspective:
www.science.org/doi/full/10....
1/2
New work from Loppin’s group found that histone eviction during sperm development ensures that paternal chromosomes aren’t mistaken for maternal chromosomes in the Drosophila embryo.
My Perspective:
www.science.org/doi/full/10....
1/2
Science | AAAS
www.science.org
November 10, 2023 at 1:10 PM
Sometimes a paper stops you in your tracks.
New work from Loppin’s group found that histone eviction during sperm development ensures that paternal chromosomes aren’t mistaken for maternal chromosomes in the Drosophila embryo.
My Perspective:
www.science.org/doi/full/10....
1/2
New work from Loppin’s group found that histone eviction during sperm development ensures that paternal chromosomes aren’t mistaken for maternal chromosomes in the Drosophila embryo.
My Perspective:
www.science.org/doi/full/10....
1/2