Lightnews — Scholar-powered news

Lindsay K Pino @lindsaykpino.com · 15h

On my way back to Seattle after my first Forbeck Forum at the beautiful Lake Geneva. Really interesting conference format: <20 people, 45 minutes to "present", maximum TWO slides. Lots of good discussion and I learned a ton -- and probably got myself into even more work/collaborations 😂

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Reposted by Lindsay K Pino

Ronald Beavis ❌ @ronbeavis.bsky.social · 1d

All proteins matter!
www.cell.com/iscience/ful...

Overcoming research bias: The untapped potential of biomedically important but understudied proteins

Biochemistry; Medical biochemistry; Omics; Proteomics

www.cell.com

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Lindsay K Pino @lindsaykpino.com · 2d

Prefer tweetorial-style tldr? Got you, too. bsky.app/profile/lind...

Lindsay K Pino @lindsaykpino.com · Jul 2

Here we go, my first skeet-torial(?) on Bluesky for my first paper from @talusbio.bsky.social !

www.biorxiv.org/content/10.1...

This preprint describes our scalable, mass spec-based method for measuring which (and how many of them) proteins are interacting with DNA.

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Native, Spatiotemporal Profiling of the Global Human Regulome

The regulome, comprising transcription factors, cofactors, chromatin remodelers, and other regulatory proteins, forms the core machinery by which cells interpret signals and execute gene expression pr...

www.biorxiv.org

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Lindsay K Pino @lindsaykpino.com · 2d

Still got our latest preprint bookmarked in an unread tab of your browser? We got you. @afederation.bsky.social presenting @talusbio.bsky.social's work-in-progress on Wednesday! 🧬 🖥️ 🧪 #MassSpectrometry #Proteomics

FragileNucleosome @fnucleosome.bsky.social · 2d

🎃 🥁This Wednesday in our 1st session of spookiest month👻 at #FragileNucleosome seminar, we are excited to host @sanimr.bsky.social & Alex Federation!
Register here for upcoming session and the entire series:
us06web.zoom.us/webinar/regi...

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Reposted by Lindsay K Pino

Andrew Iwaniuk @evoneuro.bsky.social · 2d

I am going to repost our job ad because we are not getting many applicants!
Like anywhere, there are pros and cons, so if you have questions just DM or email me.
#academicjobs #neuroskyence #neuroethology #academicsky

Andrew Iwaniuk @evoneuro.bsky.social · Sep 4

For anyone on the neuroscience job market, our ads are up. We are looking for anyone working in systems neuroscience of animals to join us in southern Alberta 🇨🇦
#academicsky #neuroskyence #neuroethology #academicjobs #Canada
neurojobs.sfn.org/job/39049/as...

Assistant Professor (Neuroscience, Tenure Track) - Lethbridge (City), Alberta (CA) job with University of Lethbridge | 39049

Assistant Professor (tenure track) of the Department of Neuroscience at the University of Lethbridge, Alberta, Canada

neurojobs.sfn.org

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Reposted by Lindsay K Pino

Ana Martínez del Val @anamdv.bsky.social · 2d

Do you have an exciting experiment that you'd love to do using proteomics in the context of your work? YPIC funds 5000 eur for your research idea to come to life!

⬇️⬇️⬇️⬇️⬇️

ypic.bsky.social @ypic.bsky.social · 15d

🎉 Exciting opportunity for students in proteomics! 🎉
The Student Proteomics Fund (SPF) is back!

📅 Key dates:
Call opens: October 1, 2025
Submission deadline: November 30, 2025
Don’t miss your chance to bring your research idea to life!
New boost
#SPF #YPIC #Proteomics

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Reposted by Lindsay K Pino

Johannes Rainer @jorainer.bsky.social · 2d

Reminder 👇

Interested in improving our R tools for #MassSpectrometry data analysis and integrating them into Galaxy?

⏲️ 3 year position
📍 Bolzano, 🇮🇹

👉 apply if you like:

- #rstats SW development
- @bioconductor.bsky.social
- large-scale #metabolomics data analysis
- hiking ⛰️

🔗 bit.ly/46AMawx

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Lindsay K Pino @lindsaykpino.com · 2d

Fair enough. And true. I'm reluctant to tell people "it isn't possible with current technology" but also reluctant to hand over data that might send some poor grad student or postdoc on a 4 year rabbit hole trying to tie what turns out to be a technical artifact to physiological relevance.

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PastelBio @pastelbio.bsky.social · 3d

Illuminating the Druggable Proteome with an AI Protein Profiling Platform www.researchsquare.c...

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#proteomics #prot-preprint

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Lindsay K Pino @lindsaykpino.com · 3d

@dbwilburn.bsky.social oh you are on bluesky

Reposted by Lindsay K Pino

SCIENMAG @scienmag.bsky.social · 3d

Boosting Malonylation Site Detection with AlphaFold2

In the ongoing evolution of proteomics, understanding post-translational modifications (PTMs) has become critical. Among these modifications, malonylation, a less commonly studied yet impactful alteration of lysine residues on proteins, presents…

Boosting Malonylation Site Detection with AlphaFold2

In the ongoing evolution of proteomics, understanding post-translational modifications (PTMs) has become critical. Among these modifications, malonylation, a less commonly studied yet impactful alteration of lysine residues on proteins, presents intriguing opportunities for further inquiry. Recognizing and mapping these malonylation sites is not merely an academic exercise; it carries implications for deciphering various biological processes and disease mechanisms. In their recent work, researchers Xu, Qian, and Yang propose a novel methodology that combines AlphaFold2, an advanced protein structure prediction tool, with ensemble learning algorithms to enhance the identification of malonylation sites significantly.

scienmag.com

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Reposted by Lindsay K Pino

Ronald Beavis ❌ @ronbeavis.bsky.social · 3d

I am always more than a little skeptical when someone characterizes phosphorylation acceptor either observed or not (0/1). Pretty much the definition of a base rate fallacy. #proteomics

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Lindsay K Pino @lindsaykpino.com · 3d

Any recommendations for how best to report? I've been thinking about mod reporting from a histone PTM perspective last week and the combinatorics seems... problematic.

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Reposted by Lindsay K Pino

Prof Sam Illingworth @samillingworth.com · 4d

🥧 Silicone bakeware and chemical exposure

A study found that silicone baking trays release cyclic siloxanes into food and air during baking, with young children facing the highest exposure.

🔗 www.sciencedirect.com/science/arti...

#SciComm #Toxicology 🧪

Silicone bakeware as a source of human exposure to cyclic siloxanes via inhalation and baked food consumption

Silicone-based bakeware is widely used due to its heat resistance, flexibility, and non-stick properties. However, concerns have emerged regarding the…

www.sciencedirect.com

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Reposted by Lindsay K Pino

Cancer Research UK Manchester Institute @cruk-mi.bsky.social · 5d

Finally, we're looking for someone to join our #MassSpec Core Facility to support all the protein/peptide MS & development needs of our research groups utilising:

🧪Protein chemistry
📈Liquid chromatography
⚛️Tandem mass spectrometry
🖥️Data analysis

More at:
www.cruk.manchester.ac.uk/career/mi-25...

Mass Spec

xkcd.com

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Reposted by Lindsay K Pino

Chris Ashwood @cashwood.proteaglyco.com · 5d

Good to see better integration of (low bias) industry employees within publishing and scientific societies.

Kermit Murray @kkmurray.bsky.social · 5d

(JASMS) [ASAP] ASMS from an Editor-in-Chief’s Perspective: Welcoming an Industrial Associate Editor to the JASMS Team: Journal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.5c00291 (RSS) #MassSpecRSS #JASMS

[ASAP] ASMS from an Editor-in-Chief’s Perspective: Welcoming an Industrial Associate Editor to the JASMS Team

Journal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.5c00291

dlvr.it

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Lindsay K Pino @lindsaykpino.com · 5d

Me to my future self as I write a wildly ambitious abstract that I now will have to make possible

a man in a suit and tie is standing next to another man in a yellow shirt and tie .

ALT: a man in a suit and tie is standing next to another man in a yellow shirt and tie .

media.tenor.com

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Reposted by Lindsay K Pino

Ruth Huttenhain @rhuttenhain.bsky.social · 6d

My lab @stanfordmedicine.bsky.social is recruiting! We are looking for a postdoc at the interface of quantitative proteomics and G protein-coupled receptor (GPCR) biology:
postdocs.stanford.edu/prospective/...
#TeamMassSpec #Proteomics #GPCR #Postdoc

Open Postdoctoral position, faculty mentor Ruth Huttenhain | Office of Postdoctoral Affairs

postdocs.stanford.edu

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Reposted by Lindsay K Pino

Biognosys @biognosys.bsky.social · 5d

📢 Only a few days left until our Fall Proteomics Social in Boston!🍂 Join us to network and learn how next-generation #proteomics can answer your research questions.

Save your spot here👉 biognosys.com/conferences/...

#Biomarkers #DrugDiscovery #DrugDevelopment

Fall Proteomics Social

Join us for an engaging evening of networking and science on October 9 in Boston, MA!

biognosys.com

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Lindsay K Pino @lindsaykpino.com · 5d

Finally listened to this one and you were joking. It is a lot of hockey ahha

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Reposted by Lindsay K Pino

R/Proteomics @r-proteomics.bsky.social · 6d

#proteomics choose your fighter!

www.reddit.com/r/proteomics...

From the proteomics community on Reddit

Explore this post and more from the proteomics community

www.reddit.com

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Reposted by Lindsay K Pino

Nautilus Biotechnology @nautilus.bio · 7d

Next Thursday, October 9th at 11:15am ET, Nautilus Co-Founder and Chief Scientist Parag Mallick will join a panel at Fierce Biotech Week to discuss:

🗣️ How Biotechs Are Leveraging AI/ML to Drive Efficiency and ROI

www.fiercebiotechweek.com/event/fierce...

#ArtificialIntelligence #MachineLearning

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Reposted by Lindsay K Pino

Chris Ashwood @cashwood.proteaglyco.com · 7d

The small molecule course starts next week, registration closes soon!
We've got an amazing keynote from Gary Patti scheduled:
Metabolomics at the Population Scale: the Pie in the Sky(line)

As well as instructors across the world taking you through tips and tricks to make Skyline work for you.

Chris Ashwood @cashwood.proteaglyco.com · 16d

Looking to master Skyline but lack time? Skyline Online returns!

Join our accelerated Small Molecule course Oct 8-10, 9am-5pm EST, covering comprehensive Skyline applications in metabolomics, lipidomics, and beyond for MS data from any major vendor.

Just $175 USD to go from intro to expert.

S1 and 2 - Intro and Advanced Small Molecule Topics: /home/software/Skyline/events/2025-10 Skyline Online

skyline.ms

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Reposted by Lindsay K Pino

Chris Ashwood @cashwood.proteaglyco.com · 10d

A new Tribrid next year, suggest two patents made public simultaneously, representing improved full Orbitrap scan range and more accurate Orbitrap ion measurement:
1. C-trap improvement from 15x lowest mass, to 40x lowest mass
2. Using the LIT to count ions for accurate AGC on the Orbitrap

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Lindsay K Pino @lindsaykpino.com · 13d

I do!! My dream would be a "see through" spec but most of the guys are encased in metal boxes anyway so it probably wouldn't be that interesting I guess

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