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Reposted by Lucas Bouys

European Journal of Endocrinology @eurojendo.bsky.social · 29d

Unexpected discrepancies between steroid intra-tissular content in adrenal tumors and clinical diagnosis of steroid excess by Fidéline Bonnet-Serrano et al

EJE Volume 193, Issue 1, July 2025
Full article 👉 doi.org/10.1093/ejen...
ESE members free via 👉 my.ese-hormones.org

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Reposted by Lucas Bouys

Wiebke Arlt @wiebkearlt.bsky.social · Sep 3

An article in the BMJ just highlighted the free fall in clinician scientist numbers www.bmj.com/content/390/... - a catastrophe in waiting for health! At the @mrc-lms.bsky.social we support next gen clinician scientists in discovery research and experimental medicine
lms.mrc.ac.uk/work-and-stu...

Chain Florey Clinician Scientist Programme

The Chain Florey programmes allow clinicians at all stages of their careers to experience research and flourish in a dual career.

lms.mrc.ac.uk

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Reposted by Lucas Bouys

MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · Aug 21

🚀 Exciting Research Assistant opportunity!

Join Dr Melanie Chan’s team at the LMS as a Research Assistant to uncover the genetics of kidney disease using cutting-edge genomics and bioinformatics!

Apply here 👇

Research Assistant - MRC Laboratory of Medical Sciences

Research Assistant to support Dr Melanie Chan

lms.mrc.ac.uk

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Reposted by Lucas Bouys

Jeunes Endocrinologues Dynamiques et Innovants (JEDI-SFE) @jedi-sfe.bsky.social · Aug 5

Le 41ème Congrès de la @sfendocrino.bsky.social à Lille, c’est dans 50 jours 📆 ! Les inscriptions restent ouvertes !

Et rejoignez nous pour la Soirée des Jeunes de la SFE du mercredi 24/09 pour passer un moment convivial et fun : on vous attend nombreux 😇 ! Des surprises et cadeaux sont prévus 😎 !

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Reposted by Lucas Bouys

Vicki Metzis @vmetzis.bsky.social · Aug 1

Application deadline for up to 5 @mrc-lms.bsky.social postdoc positions in developmental epigenetics closes soon - don’t miss out! Positions across both experimental and computational projects. Come and join our fantastic team science community!

Vicki Metzis @vmetzis.bsky.social · Jul 14

Interested in developmental epigenetics? So are we! Apply now to join us for your postdoc!

Multiple positions across multiple groups @mrc-lms.bsky.social

Projects spanning germline demethylation, gene regulation, genome architecture in development & disease 👇👇

lms.mrc.ac.uk/work/vacanci...

MRC Postdoctoral Research Scientists x 5 - MRC Laboratory of Medical Sciences

Applications are now open for up to five postdoctoral positions in the area of developmental epigenetics.

lms.mrc.ac.uk

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Reposted by Lucas Bouys

Vicki Metzis @vmetzis.bsky.social · Jul 14

Interested in developmental epigenetics? So are we! Apply now to join us for your postdoc!

Multiple positions across multiple groups @mrc-lms.bsky.social

Projects spanning germline demethylation, gene regulation, genome architecture in development & disease 👇👇

lms.mrc.ac.uk/work/vacanci...

MRC Postdoctoral Research Scientists x 5 - MRC Laboratory of Medical Sciences

Applications are now open for up to five postdoctoral positions in the area of developmental epigenetics.

lms.mrc.ac.uk

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Reposted by Lucas Bouys

MRC Laboratory of Medical Sciences @mrc-lms.bsky.social · May 22

We’re excited to welcome tesscacciottolo.bsky.social and lucasbouys.bsky.social to our Chain Florey Clinician Scientist Programme at the LMS!

This programme offers world-class training to clinicians to develop essential research skills at key stages of their careers.

Introducing: Dr Tessa Cacciottolo and Dr Lucas Bouys

We’re excited to welcome Dr Tessa Cacciottolo and Dr Lucas Bouys to the MRC Laboratory of Medical Sciences (LMS) as part of the Chain Florey Clinician Scientist Programme. Both are part of the Transit...

lms.mrc.ac.uk

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Reposted by Lucas Bouys

Cristina L Ronchi @cronchi.bsky.social · May 12

Day 2 at joint esendocrinology.bsky.social and #ESPE #ECE2025 in #Copenhagen #becausehormonesmatter #connectingendocrinology #EndocrinologyAcrossTheLifeCourse #MedSky #EndoSky

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Reposted by Lucas Bouys

The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · May 12

Mild autonomous cortisol secretion (MACS) associated with #unilateral #adrenal #incidentalomas is responsible for secondary #hypertension that can be safely improved by minimally-invasive #adrenalectomy www.thelancet.com/journals/lan...

#MedSky #EndoSky #OncSky #CardioSky

Surgery for the treatment of arterial hypertension in patients with unilateral adrenal incidentalomas and mild autonomous cortisol secretion (CHIRACIC): a multicentre, open-label, superiority randomis...

MACS associated with unilateral adrenal incidentalomas is responsible for secondary hypertension that can be safely improved by minimally-invasive adrenalectomy.

www.thelancet.com

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Lucas Bouys @lucasbouys.bsky.social · Mar 14

Amazing #ChainFlorey Retreat Day! happy to be part of this exciting community of young #clinicianscientists

Wiebke Arlt @wiebkearlt.bsky.social · Mar 14

Great day with the amazing early career #clinicianscientists of the @mrc-lms.bsky.social #ChainFlorey cohort doing discovery science & experimental medicine - join us! lms.mrc.ac.uk/work-and-stu...

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Reposted by Lucas Bouys

Nature Reviews Endocrinology @natrevendo.nature.com · Mar 12

ICYMI: New content online: Adrenocortical stem cells in health and disease

Adrenocortical stem cells in health and disease

Nature Reviews Endocrinology, Published online: 10 March 2025; doi:10.1038/s41574-025-01091-2This Review outlines the mechanisms that regulate the establishment and maintenance of the adrenal stem cell niche — comprising capsular stem cells and cortical…

www.nature.com

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Reposted by Lucas Bouys

The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · Mar 12

New Review by Martin Fassnacht & colleagues:
Adrenocortical carcinoma: a practical guide for clinicians thelancet.com/journals/lan...
#adrenocortical #carcinoma #adrenal
#OpenAccess
#MedSky #EndoSky #OncSky

Adrenocortical carcinoma: a practical guide for clinicians

Adrenocortical carcinoma is a rare endocrine malignancy. The management of patients with adrenocortical carcinoma is challenging for several reasons, including its heterogeneous but frequently aggress...

thelancet.com

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Reposted by Lucas Bouys

Simply Railway @simplyrailways.bsky.social · Mar 11

This morning, @sncf-voyageurs.bsky.social and @alstom.bsky.social finally unveiled the brand-new #TGVM to the public!

Let’s take a look inside the latest generation of high-speed trains 🚄🇫🇷

A thread 👇

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Reposted by Lucas Bouys

European Society of Endocrinology @esendocrinology.bsky.social · Mar 10

Late breaking abstract submission for the Joint Congress of ESPE and ESE 2025 opens today 10 March!

Share new data, exciting breakthroughs or innovations before the deadline 21 March 2025.

Submit your abstract now👉 bit.ly/3PXTqcB

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Lucas Bouys @lucasbouys.bsky.social · Feb 28

Crucial findings, a must read for all those interested in tumour suppressor genes 🧬 Simple but impactful 👊
Released this week in Nature Genetics @naturegenet.bsky.social

rdcu.be/ebIiO

Cancer-independent somatic mutation of the wild-type NF1 allele in normal tissues in neurofibromatosis type 1

Nature Genetics - Histologically normal tissues of individuals with a germline NF1 mutation exhibited multiple second NF1 hits, unrelated to their tumors, that conferred a selective advantage.

rdcu.be

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Reposted by Lucas Bouys

European Society of Endocrinology @esendocrinology.bsky.social · Feb 28

Today is #RareDiseaseDay!

There are more than 400 rare diseases related to the endocrine system, which affect more than 30 million Europeans.

Find out more👉 rarediseaseday.org

#BecauseHormonesMatter

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Reposted by Lucas Bouys

Jérôme Bertherat @jeromebertherat.bsky.social · Feb 27

Glad to see this study in 4th-year Med Stud at @upcite.bsky.social : gender-equitable self-perceptions (opposing women underestimating their abilities by the past). Happy to have contributed as a one of the 130 included evaluators to this experiment 😀

bmcmededuc.biomedcentral.com/articles/10....

Impact of gender on self-assessment accuracy among fourth-year French medical students on faculty’s online Objective Structured Clinical Examinations - BMC Medical Education

Background Historically, women have been shown to underestimate their abilities, while men often assess themselves more accurately or overestimate. This study aims to determine self-assessment accurac...

bmcmededuc.biomedcentral.com

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Lucas Bouys @lucasbouys.bsky.social · Feb 21

2/2 KDM1A mutations are rare, they cause severe FDCS in younger patients, and affect predominantly #women: intriguing for a dominantly inherited disease ⁉️
Again, thanks to the worldwide collaborative force 🇪🇺🇧🇷🇺🇸
@institutcochin.bsky.social @hopitalcochin.bsky.social

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Lucas Bouys @lucasbouys.bsky.social · Feb 21

1/2 In late 2021 we identified KDM1A germline mutations as the genetic cause of hereditary Primary Bilateral Macronodular Adrenal Hyperplasia with food(GIP)-dependent #Cushing’s syndrome (FDCS) 🍔🍟 3 years later, we report its extensive screening in 301 index cases in @eurojendo.bsky.social 🧬

Validate User

doi.org

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Reposted by Lucas Bouys

Wiebke Arlt @wiebkearlt.bsky.social · Feb 19

Calling clinician scientists with focus on mechanistic discovery science and experimental medicine who recently have completed or are about to complete their clinical training - great opportunity! Please re-skeet and apply to @mrc-lms.bsky.social by 4th March 2025 lms.mrc.ac.uk/work/vacanci...

Chain Florey Post CCT Transition to Independence Fellowship - MRC Laboratory of Medical Sciences

The Chain Florey Transition-to-Independence (TTI) Fellowship scheme provides a unique opportunity to clinician scientists who have recently completed their clinical training (or will do so in the next...

lms.mrc.ac.uk

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Lucas Bouys @lucasbouys.bsky.social · Feb 12

The recipe for your perfect morning eggs 🥚 ⚠️ 10 pages/32 mn/2 alternating cooking temperatures/8 cycles: looks like a very simplified PCR but still for well-organised cooks only 🧑‍🍳 let’s hope that will work with other eggs than those from Naples 🤓

Nature Portfolio @natureportfolio.nature.com · Feb 12

A paper in Communications Engineering presents a new method to optimally cook both the yolk and white of a boiled chicken egg. "Periodic cooking” yields an evenly-cooked egg with a higher nutritional content than shell-on eggs cooked by conventional methods. https://go.nature.com/4hJWNzU 🧪

This is figure 4, which shows sensory analysis evaluation.

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Lucas Bouys @lucasbouys.bsky.social · Feb 12

Including 1 specific position in cardiac imaging ❤️🩻

Description

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

www.imperial.ac.uk

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Lucas Bouys @lucasbouys.bsky.social · Feb 12

Looking for your next move as a clinician-scientist? 3 positions of Transition to Independence Fellow for 3 years in @mrc-lms.bsky.social @imperialcollegeldn.bsky.social 80% protected research time + 20% clinics in an amazing scientific environment in London 👩🏻‍⚕️👨🏻‍⚕️👩🏻‍🔬👨🏻‍🔬 🧫🔬deadline 4th March! DM me for info

Description

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

www.imperial.ac.uk

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Reposted by Lucas Bouys

Declan O’Regan @drdeclanoregan.bsky.social · Feb 11

❤️Three year fully-funded post-CCT fellowship in Cardiac imaging / AI at @mrc-lms.bsky.social and @imperialcollegeldn.bsky.social. The Chain Florey Transition to Independence scheme offers a unique opportunity for early career clinicians. Closes 2nd March! www.imperial.ac.uk/jobs/search-...

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Lucas Bouys @lucasbouys.bsky.social · Feb 5

Thanks to a friendly collaboration across France/Germany/UK/USA/Brazil and the COMETE and ENSAT networks 🫶 @jeromebertherat.bsky.social @geraldraverot.bsky.social
@cronchi.bsky.social and the 17 other authors not on BlueSky (how come??? 🫨)
@institutcochin.bsky.social @hopitalcochin.bsky.social

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