Matthew Stower
@m-stower.bsky.social
80 followers 100 following 9 posts
Developmental biologist at Oxford Uni, interested in how cells combine to drive morphogenesis
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Reposted by Matthew Stower
plosbiology.org
During #development, distal visceral #endoderm (DVE) cells migrate to shape A-P axis specification. @m-stower.bsky.social @srinivas-lab.bsky.social &co reveal the role of Ca2+ dynamics in this, showing that inhibition of #calcium transients causes DVE arrest @plosbiology.org 🧪 plos.io/4nHWxF4
Epiblast Ca2+ waves propagate from the apical to basal domain. The images show selected time points from movies of E5.5 GCaMP6f embryos imaged using a ZEISS lattice light-sheet 7 microscope. Top row: An example of an epiblast wave involving a large proportion of the tissue captured by imaging a volume of the embryo at 20-s intervals. A total of 9/16 embryos showed at least one epiblast Ca2+ wave. Bottom row: Faster imaging at 5-s interval revealed that the Ca2+ wave in the epiblast can be preceded by a transient in a neighboring VE cell—this was observed in 5/19 events from 9 embryos (white arrowheads).
m-stower.bsky.social
Enjoying the BSDB meeting “bridging mechanics and genetics in early development” at Warwick. A great diversity of talks
m-stower.bsky.social
My office for today!
Reposted by Matthew Stower
bertaverd.bsky.social
I am recruiting an #ERC funded PostDoc to work on the evolution of vertebral counts in cichlids. This is an experimental project & will be looking for candidates with experience generating reporter lines, live-imaging and experimental embryology.
Application deadline: 25th Feb.
tinyurl.com/33jbu8fa
m-stower.bsky.social
A great meeting. Thanks to the organisers for selecting my short talk in such a packed schedule! Great fun as ever discussing development and cell science with everyone over the last few days in Liverpool #biologists100
Reposted by Matthew Stower
vmetzis.bsky.social
“Play and share” - inspiring and important words from Manu Prakash @prakashlab.bsky.social at this morning’s session #biologists100 @biologists.bsky.social
m-stower.bsky.social
Enjoying a great meeting at the CoB@100 in Liverpool. A fun poster session yesterday evening and more interesting talks today. #biologists100
m-stower.bsky.social
In sunny Liverpool ahead of the CoB@100 conference!
m-stower.bsky.social
A wintery IDRM this morning
m-stower.bsky.social
Feeling Festive! Very happy to share our new bioRχiv pre-print – investigating the role of calcium signalling in the early mouse embryo:
www.biorxiv.org/content/10.1...
m-stower.bsky.social
Great to be at Oxford Digital Festival 2024 showcasing ‘Synchrony’ digital art work with It’s creator Andy Lomas