Lightnews — Scholar-powered news

Mallar Chakravarty @mallarchak.bsky.social · 2d

So excited for my friend, colleague, and all-around superstar of a human-being.

Keep your eyes 👀 open.

There's clearly so much awesome that will spring forward from this move.

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Reposted by Mallar Chakravarty

Greg Jefferis @jefferis.bsky.social · 3d

Exciting news for #drosophila #connectomics and #neuroscience enthusiasts: the Drosophila male central nervous system connectome is now live for exploration. Find out more at the landing page hosted by our Janelia FlyEM collaborators www.janelia.org/project-team....

Male CNS Connectome

A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system —a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the ...

www.janelia.org

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Mallar Chakravarty @mallarchak.bsky.social · 6d

Check out this great summary of our recent paper on the impact of exposure to #THC during gestation.

Thanks @douglasresearch.bsky.social !!

Orig paper here:

www.nature.com/articles/s41...

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Reposted by Mallar Chakravarty

Douglas Research Centre @douglasresearch.bsky.social · 6d

BREAKING SCIENCE
Prenatal cannabis exposure and brain development : a new study from the Chakravarty Lab.

➡️ Swipe through the carousel to discover the study in a simple and accessible way!

Learn more : douglas.research.mcgill.ca/news/chakrav...

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Mallar Chakravarty @mallarchak.bsky.social · 6d

Thanks for all your hard work @haleyv.bsky.social !!

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Mallar Chakravarty @mallarchak.bsky.social · 6d

Many thanks to collaborators @haleyv.bsky.social and the Marie-Ève Tremblay lab for their amazing commitment and collaboration on the electron microscopy. Also many thanks to the rest of the authors for their contribs!

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Mallar Chakravarty @mallarchak.bsky.social · 6d

Overall we see subtle developmental and neurodevelopmental variation that require far more examination about their functional consequences. But we believe that his provides and excellent lifespan baseline for the impact of prenatal #THC exposure

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Mallar Chakravarty @mallarchak.bsky.social · 6d

during gestation, when examining the hippocampi using electron microscopy we observed a high number of dividing cells

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Mallar Chakravarty @mallarchak.bsky.social · 6d

Behaviourally we observed:

1) females showed more characteristics of distress with fewer long calls and more calls overall
2) females showed difference in total distance moved and time spent in the center of the open field

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Mallar Chakravarty @mallarchak.bsky.social · 6d

Mouse brain development showed:

1) Larger ventricles during the gestational period.
2)Show decelerated brain growth in early life
3) Females show lower brain volumes and growth in key regions like thalamus and amygdala

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Mallar Chakravarty @mallarchak.bsky.social · 6d

Mice were

1) smaller during gestation
2) underwent accelerated growth (as indexed by weight) after they are born
2) female mice stay underweight once they reach adulthood and male mice catch up

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Mallar Chakravarty @mallarchak.bsky.social · 6d

We examine three cohorts of mice:

1) At late fetal stages
2) Early on in post-natal development
3) After weaning all the until post-natal day 90

We used a combination of maternal observations, stage appropriate behaviours, and longitudinal MRI postnatally

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Mallar Chakravarty @mallarchak.bsky.social · 6d

Excited to share our new publication on the impact of #THC exposure during gestation on brain development. This stunning work, led by Lani Cupo, describes several years of datas collection and examines brain development and maturation using MRI and behaviour

www.nature.com/articles/s41...

👇🏾👇🏾👇🏾👇🏾

Impact of prenatal delta-9-tetrahydrocannabinol exposure on mouse brain development: a fetal-to-adulthood magnetic resonance imaging study - Molecular Psychiatry

Molecular Psychiatry - Impact of prenatal delta-9-tetrahydrocannabinol exposure on mouse brain development: a fetal-to-adulthood magnetic resonance imaging study

www.nature.com

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Reposted by Mallar Chakravarty

Pedro Pimentel-Coelho @ppimentel-coelho.bsky.social · 16d

Impact of prenatal delta-9-tetrahydrocannabinol exposure on mouse brain development: a fetal-to-adulthood magnetic resonance imaging study

Lani Cupo et al. 🧪

www.nature.com/articles/s41...

Impact of prenatal delta-9-tetrahydrocannabinol exposure on mouse brain development: a fetal-to-adulthood magnetic resonance imaging study - Molecular Psychiatry

Molecular Psychiatry - Impact of prenatal delta-9-tetrahydrocannabinol exposure on mouse brain development: a fetal-to-adulthood magnetic resonance imaging study

www.nature.com

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Mallar Chakravarty @mallarchak.bsky.social · 11d

Just a 🔥study by @hyolee.bsky.social and @bogglerapture.bsky.social on morphological sex diffs and their mechanistic basis.

Important findings and cool methods.

Hyo Lee @hyolee.bsky.social · 15d

Humans show reproducible sex differences in regional cortical volume but what are their morphological and mechanistic bases?

Our new preprint approaches this question by separate analysis of cortical volume, area and thickness, and examining data from rare patient cohorts 👀 🧵⬇️

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Reposted by Mallar Chakravarty

Hyo Lee @hyolee.bsky.social · 15d

7. I thank all study participants and the team! @bogglerapture.bsky.social, @konradwagstyl.bsky.social, @mallarchak.bsky.social, @coevolvinglab.bsky.social + others not on BlueSky. Preprint: doi.org/10.1101/2025.09.10.675377

Also…

doi.org

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Reposted by Mallar Chakravarty

Hyo Lee @hyolee.bsky.social · 15d

Humans show reproducible sex differences in regional cortical volume but what are their morphological and mechanistic bases?

Our new preprint approaches this question by separate analysis of cortical volume, area and thickness, and examining data from rare patient cohorts 👀 🧵⬇️

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Reposted by Mallar Chakravarty

Kevin Sitek @sitek.bsky.social · 22d

Healthy scientific communities—built on open, engaged communication—are ready to take on the next challenges facing broader society.

Had a blast writing this piece with @dupre.science and @alfiewearn.bsky.social. Many thanks to the other past @ohbm-com.com chairs for their feedback and support!

Aperture Neuro @apertureohbm.bsky.social · 26d

Kicking off the Future of Scientific Publishing Special Issue, former @ohbm-com.com Chairs highlight the importance of effective science communication: doi.org/10.52294/001...

@sitek.bsky.social @alfiewearn.bsky.social @dupre.science @ohbmofficial.bsky.social

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Mallar Chakravarty @mallarchak.bsky.social · 28d

So excited to give this a read! I've seen @gozziale.bsky.social present this work and it's just so elegant!

Alessandro Gozzi @gozziale.bsky.social · 28d

🚨 Excited to share the latest preprint form the lab ➡️https://tinyurl.com/32d3be9f

Here we tackle a long-standing chicken-or-egg 🐣🥚question in #autism and developmental neuroscience

➡️ Is excitation–inhibition (E:I) imbalance a "cause" or a "consequence" of #autism?

Check out what we found!
🧵1/n

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Reposted by Mallar Chakravarty

Alex Fornito @alexfornito.bsky.social · Sep 5

Big thanks to our fab organising committee:
@toddc.bsky.social
@mallarchak.bsky.social
J Cabral
J Bijsterbosch
@bttyeo.bsky.social
@lucinauddin.bsky.social
@drbreaky.bsky.social
M Woolrich
D Margulies

@nsb-lab.bsky.social

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Reposted by Mallar Chakravarty

Imaging Neuroscience @imagingneurosci.bsky.social · Sep 5

Launched in 2023, Imaging Neuroscience is now firmly established, with full indexing (PubMed, etc.) and 700 papers to date.

We're very happy to announce that we are able to reduce the APC to $1400.

Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.

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Reposted by Mallar Chakravarty

Aperture Neuro @apertureohbm.bsky.social · Aug 18

Lugtmeijer et al. highlight key events from the Open Science Room at the 2024 Annual Meeting in Seoul, Korea: doi.org/10.52294/001...

@selmalugtmeijer.bsky.social @ohbmossig.bsky.social @fmri-today.bsky.social @mallarchak.bsky.social @ohbmofficial.bsky.social

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Reposted by Mallar Chakravarty

Jibran Khokhar @drjkhokhar.bsky.social · Aug 18

For those following alone on #CannabinoidGRC2025, here is the starter pack to stay on top of the latest and greatest in cannabis science go.bsky.app/JmeZk14

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Mallar Chakravarty @mallarchak.bsky.social · Aug 13

This is a great opportunity amplify the hard work that went into your abstract. In your cover letter let us know that you presented this at @ohbmofficial.bsky.social 2025 in Brisbane.

This is your community journal that here to improve the impact of your work!

👇👇

Aperture Neuro @apertureohbm.bsky.social · Aug 5

Whether you're in a writing phase or catching up post-conference, don’t let your abstract sit - take the next step.

Aperture Neuro offers:
✔️ Open access
✔️ Support for diverse research outputs
✔️ Acceptance of null results and replication studies

📄 Submit here: apertureneuro.org/for-authors

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Reposted by Mallar Chakravarty

Aperture Neuro @apertureohbm.bsky.social · Aug 11

Eierud et al. develop multivariate molecular imaging brain atlases using the NeuroMark PET ICA framework: doi.org/10.52294/001...

@fmri-today.bsky.social @mallarchak.bsky.social @vcalhoun.bsky.social

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