Manuel González Fuente
@manuelgonzalezfuen.bsky.social
230 followers 310 following 32 posts
Postdoctoral researcherer at #TheUstunLab in @ruhr-uni-bochum.de working on P-bodies and bacterial pathogens. 🏳️‍🌈 he/him
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manuelgonzalezfuen.bsky.social
It is with great pleasure that I inaugurate my Bluesky account sharing our last @biorxiv-plants.bsky.social at @theustunlab.bsky.social, about pathogen-mediated modulation of host P-bodies and translation. 🆕 🎉

www.biorxiv.org/content/10.1...

🧵 (1/14)
Reposted by Manuel González Fuente
theustunlab.bsky.social
We recently celebrated the 7th anniversary of @theustunlab.bsky.social with a barbecue! Our journey began in Tübingen in September 2018 and has continued in Bochum since 2022. Excited to see what the coming years will bring!
Reposted by Manuel González Fuente
geminiteamlab.bsky.social
Incredibly happy and proud of our Chaonan Shi (chaonan123.bsky.social ), who successfully defended her doctoral thesis yesterday at the @zmbp-tuebingen.bsky.social ! (And what a brilliant defence it was!) 🥳🥳🥳 Congratulations, Dr Shi!!! 🍾🥂🍋‍🟩🌶️ We are so lucky to have you in our team ❤️
Reposted by Manuel González Fuente
davidbiermann.bsky.social
Very excited to share that our paper "A RALF-brassinosteorid signaling circuit regulates Arabidopsis hypocotyl cell shape" is now published in @currentbiology.bsky.social !

Enjoy reading it!!

www.sciencedirect.com/science/arti...
Reposted by Manuel González Fuente
suaybuestuen.bsky.social
7 years ago,I sat outside @zmbp-tuebingen.bsky.social,gathering the courage to begin a new chapter as a group leader. Now in Bochum, I still need that courage to face challenges—both inside & outside the lab—but after all I’m grateful that I still find joy in what I do. #happybirthday #theustunlab
Reposted by Manuel González Fuente
zoom.earth
🔥 Fires in Portugal and Spain have sent huge plumes of smoke over the Bay of Biscay this morning. White is clouds, light brown is smoke:
Reposted by Manuel González Fuente
suaybuestuen.bsky.social
We (@manuelgonzalezfuen.bsky.social @margotraffeiner.bsky.social @shanshuo.bsky.social) had a fantastic #2025ISMPMI in Cologne with lots of amazing science and great networking meeting old friends and new ones. Hope to see you all next time in Jeju/South Korea #2027ISMPMI
Reposted by Manuel González Fuente
morgancarterphd.bsky.social
It is depressing to be at an international conference and have everyone be like “what is going on over there”. 🫠 Not exactly making America great.
Reposted by Manuel González Fuente
suaybuestuen.bsky.social
Next in the concurrent session “spatial and temporal session” is @type3lab.bsky.social who will talk about their amazing findings on distinct pseudomonas subpopulations that cooperate to colonize plants #2025ISMPMI
Reposted by Manuel González Fuente
suaybuestuen.bsky.social
If you wanna dive into the world of #proteostasis and its role in plant immunity, visit @margotraffeiner.bsky.social poster (P-405) today. She discovered a novel proteotoxicity regulator (a protease with ubiquitin binding capacities) that plays a role in biotic and abiotic stresses! #2025ISMPMI
Reposted by Manuel González Fuente
margotraffeiner.bsky.social
Happy to meet you at poster no. P-405 and to talk about my project at #2025ISMPMI this afternoon! 🌿
suaybuestuen.bsky.social
If you wanna dive into the world of #proteostasis and its role in plant immunity, visit @margotraffeiner.bsky.social poster (P-405) today. She discovered a novel proteotoxicity regulator (a protease with ubiquitin binding capacities) that plays a role in biotic and abiotic stresses! #2025ISMPMI
Reposted by Manuel González Fuente
theustunlab.bsky.social
Last day of #2025ISMPMI, last poster session: dont miss @shanshuo.bsky.social fantastic poster about how we used a combination of scRNAseq and cell-type specific approaches to reveal the role of autophagy in stomatal & mesophyll immunity during Pseudomonas infection - more info ➡️ P-432 #proteostasis
Reposted by Manuel González Fuente
suaybuestuen.bsky.social
Hannah @mcmicrobes.bsky.social will start her own lab in 2026 (congrats a lot 🥳)- watch out for some job postings in the future - she will continue to work on heat stress and the effect on leaf-microbioata! #2025ISMPMI
Reposted by Manuel González Fuente
suaybuestuen.bsky.social
Sheng Yang leaves the stage for @mcmicrobes.bsky.social who continues to talk about her exciting results on how abiotic stress impacts the leaf-microbiome #2025ISMPMI
Reposted by Manuel González Fuente
suaybuestuen.bsky.social
We start the last day of #2025ISMPMI with Renier van der Hoorn who will present his pioneering work on how pathogens manipulate apoplastic defence
Reposted by Manuel González Fuente
effectomics.bsky.social
#2025ISMPMI Manuel Gonzalez Fuente from the Üstün lab shows how pathogens like Pseudomonas target p bodies with effectors HopM1 and HopN1. ER stress induction by HopM1 counteracts p bodies.
Reposted by Manuel González Fuente
suaybuestuen.bsky.social
Enjoying the free afternoon in Cologne at #2025ISMPMI with @manuelgonzalezfuen.bsky.social @margotraffeiner.bsky.social and Christa 🥂
manuelgonzalezfuen.bsky.social
Thank you very much Carmen! 🙏
Reposted by Manuel González Fuente
morgancarterphd.bsky.social
@manuelgonzalezfuen.bsky.social explains that eukaryote P bodies contain translationally inactive RNAs.

Do pathogens induce the formation of these? Yes!

How? Effectors!… that repress ER stress response.

Why? Make plants susceptible by reducing translation of immunity genes.
#2025ISMPMI
A person presenting a scientific talk showing a slide quantifying P bodies through microscopy
Reposted by Manuel González Fuente
suaybuestuen.bsky.social
Now @manuelgonzalezfuen.bsky.social is on stage presenting his exciting project on p-bodies, and how bacteria utilize them to attenuate host translation #proteostasis #2025ISMPMI
manuelgonzalezfuen.bsky.social
It's okay, you have already seen it 😅
But we are sad that you couldn't join this year... Hope to coincide again soon!
manuelgonzalezfuen.bsky.social
If you want to hear about our latest work at @suaybuestuen.bsky.social's lab on pathogen manipulation of host translation and P-bodies at #2025ISMPMI, pass by my presentation today at 12:20 in the concurrent session "Effector interference mechanism" (Room M+N).
Reposted by Manuel González Fuente
suaybuestuen.bsky.social
Great to see @geminiteamlab.bsky.social and @bactodeath.bsky.social presenting a lot of unpublished data, new concepts and approaches in plant-microbe interactions! This should be the spirit at this meeting! Very cool plenary session at #2025ISMPMI
Reposted by Manuel González Fuente
suaybuestuen.bsky.social
@manuelgonzalezfuen.bsky.social will talk about how bacteria exploit P-bodies to attenuate host translation

@margotraffeiner.bsky.social presents a novel proteotoxicity regulator and its role in plant immunty

@shanshuo.bsky.social will emphasize the role of autophagy in stomatal immunity