Lightnews — Scholar-powered news

Maria Viola @mariafviola.bsky.social · 22d

Had the wonderful opportunity to present our data on the effect of microplastics on macrophages at #EMDS2025 ! Such a beautiful venue 🤩 @masslab.bsky.social

Andrew S. MacDonald @profandrewmac.bsky.social · 22d

Fascinating (and disturbing!) presentation about the impact of ingested microplastics on liver macrophages by @mariafviola.bsky.social #EMDS2025

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Reposted by Maria Viola

Nina Cabezas-Wallscheid @ninacabezas.bsky.social · Jul 16

🔥NEW paper from our lab! Ever wondered how the metabolite/lipid composition of human bone marrow HSCs changes during differentiation,aging,AML? Check our work www.nature.com/articles/s41... driven by the brilliant Marialena & Maricarmen with Jörg! @mpi-ie.bsky.social @ethz.ch @natcellbio.nature.com

Differentiation, ageing and leukaemia alter the metabolic profile of human bone marrow haematopoietic stem and progenitor cells - Nature Cell Biology

Lalioti, Romero-Mulero et al. combine metabolomics, lipidomics and transcriptomics of haematopoietic stem and progenitor cells during differentiation, ageing and leukaemia, finding a role for choline ...

www.nature.com

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Reposted by Maria Viola

Nature @nature.com · Jun 19

Nature research paper: Kupffer cell programming by maternal obesity triggers fatty liver disease

https://go.nature.com/4laOA9s

Kupffer cell programming by maternal obesity triggers fatty liver disease - Nature

In a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.

go.nature.com

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Maria Viola @mariafviola.bsky.social · Jun 18

It‘s finally out!!! ⬇️

Mass Lab @masslab.bsky.social · Jun 18

We are SO EXCITED to share our story @nature.com:
🧵1/
Maternal obesity reprograms fetal liver macrophages, triggering adult fatty liver disease in the offspring.
This study uncovers how Kupffer cells act as intergenerational messengers in metabolic disease.
👉 Read here: rdcu.be/erD3b

Kupffer cell programming by maternal obesity triggers fatty liver disease

Nature - In a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.

rdcu.be

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Reposted by Maria Viola

Mass Lab @masslab.bsky.social · May 7

Just presented our story on #KupfferCells #liver & #microplastics togehter with @mariafviola.bsky.social in the basic science session @ #EASL2025 in #Amsterdam. Great format to promote ECRs and for fantastic discussions with scientists and clinicians!

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Reposted by Maria Viola

Mass Lab @masslab.bsky.social · Apr 23

Read our newest publication @jem.org about #microglia and #CD8Tcell interactions in spastic paraplegia! 💡Immune activation happens before #neuronal loss! 💡
Team effort with the labs of Marc Beyer and Ralf Stumm 👇
doi.org/10.1084/jem....
@limes-bonn.bsky.social @immunosens.bsky.social #immunosky

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Maria Viola @mariafviola.bsky.social · Mar 18

Please check out this awesome tldr of our new preprint on micro- and nanoplastics and their effect on #macrophages and #metabolism ! So excited to share this with the world, let us know what you think ! #microplastics #nanoplastics

Mass Lab @masslab.bsky.social · Mar 18

1/ 🚨 New preprint alert! 🚨
Micro- and nanoplastics (MNPs) are everywhere, but what happens when they get inside us? Our latest study reveals how chronic plastic exposure affects macrophages and metabolism in a size-dependent manner. 🧵👇 www.researchsquare.com/article/rs-6...

Size-dependent plastic exposure disrupts macrophage function and tissue-specific metabolism

Plastic pollution is an emerging yet understudied environmental risk to the immune system. Once ingested, nano- and microplastic particles (MNPs) can translocate from the gut to internal organs, with ...

www.researchsquare.com

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Maria Viola @mariafviola.bsky.social · Feb 26

So happy this is *finally* out!

Hind Hussein, PhD @hindhussein.bsky.social · Feb 25

Our new paper is also out in Gut! gut.bmj.com/content/earl...
#Mastcells #IBS #GISky #Immunosky #MRGPRX2 #pain

Characterisation of MRGPRX2+ mast cells in irritable bowel syndrome

Background Mast cell activation is an important driver of abdominal pain in irritable bowel syndrome (IBS). While evidence supports the role of IgE-mediated mast cell activation in visceral pain devel...

gut.bmj.com

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Maria Viola @mariafviola.bsky.social · Feb 12

Try this one : authors.elsevier.com/c/1kbBf3qNrU...

authors.elsevier.com

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Maria Viola @mariafviola.bsky.social · Feb 11

Could bacterial translocation during colitis rewire the bone marrow? Check out our highlight of these cool findings by the Sancho lab ⬇️ authors.elsevier.com/a/1kbBf3qNrU...
@masslab.bsky.social

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Reposted by Maria Viola

Mass Lab @masslab.bsky.social · Feb 11

"Bacterial translocation promotes #trained #immunity" !!! 🤩
Check out our preview highlighting the beautiful peace @cp-immunity.bsky.social by the Sanches lab. With @mariafviola.bsky.social
#macrophages #Mincle authors.elsevier.com/a/1kbBf3qNrU...

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Reposted by Maria Viola

FOR5775 MagNet @for5775.bsky.social · Jan 15

Join our #MagNet #Seminar by Nicolas Venteclef! He will be talking about #epigenetics and #adipose tissue #macrophages: January 20th at 4pm CET. Enter #zoom via QR code

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Reposted by Maria Viola

Mass Lab @masslab.bsky.social · Dec 21

Are you looking for a #PhD position in the interdisciplinary field of #immunology #development #cellbiology? Do you love #macrophages? #FOR5775 is hiring!! Find details here: macrophagenetwork.com/news-2/
Pls repost👇 #immunosky

News – My WordPress

macrophagenetwork.com

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Reposted by Maria Viola

Mass Lab @masslab.bsky.social · Dec 12

We are super happy that our #FOR5775 #MagNet got funded! 🥳 Thanks to @dfgpublic.bsky.social look out for interesting #macrophage science in the coming 4 years!
www.dfg.de/de/service/p...

DFG fördert acht neue Forschungsgruppen

www.dfg.de

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Maria Viola @mariafviola.bsky.social · Dec 4

Not ✨macrophages✨ but a characterisation of a rather elusive cell type in the human colon : mast cells! Congrats @hindhussein.bsky.social , I've been looking forward to this !

Hind Hussein, PhD @hindhussein.bsky.social · Dec 4

Intro time! I'm Hind, a mucosal #immunologist working in KU Leuven on mast cells in health and in gut disease.
Speaking of, I can finally show what I have been working on for the last 4 years, ie characterizing human mast cells in layers of the colon via scRNAseq
www.biorxiv.org/content/10.1...

Single cell transcriptomics reveal mast cell heterogeneity in the human gut

Gut mast cells are key players in infection and inflammation, as well as in homeostasis. Mast cells regulate gastrointestinal (GI) function by controlling vascular and epithelial permeability, and int...

www.biorxiv.org

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Maria Viola @mariafviola.bsky.social · Nov 29

@masslab.bsky.social had a successful #EMDS2024!

Mass Lab @masslab.bsky.social · Nov 29

2 #poster #prizes for the incredible @mariafviola.bsky.social and @haohuang0086.bsky.social at #EMDS 🫶 #macrophages rock! #immunosky

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Maria Viola @mariafviola.bsky.social · Nov 27

Here again to ask you to add @haohuang0086.bsky.social who’s new to 🦋 thank you!

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Maria Viola @mariafviola.bsky.social · Nov 27

OMG #EMDS2024 what is this room 😍 @haohuang0086.bsky.social

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Reposted by Maria Viola

Toufic Mayassi @touficmayassi.bsky.social · Nov 21

1/ Keen to share the story of my postdoc research out in @natureportfolio.bsky.social! We built a massive resource characterizing the spatial landscape of the gut—and yes, we dug deep into the biology too. If you’ve got a minute, let me walk you through the story. 🧵👇
www.nature.com/articles/s41...

Spatially restricted immune and microbiota-driven adaptation of the gut - Nature

Intestinal regionalization is characterized by robust and resilient structural cell states and the intestine can adapt to environmental stress in a spatially controlled manner through crosstalk betwee...

www.nature.com

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Maria Viola @mariafviola.bsky.social · Nov 22

@masslab.bsky.social is on 🦋 ! Follow for lots of macrophage content 🤓

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Maria Viola @mariafviola.bsky.social · Nov 21

Happy to say that @masslab.bsky.social is now on Bluesky! Can you add us to the latest starter pack ? Thank you :)

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Maria Viola @mariafviola.bsky.social · Nov 19

But the villi are like sooo straight. It’s so impressive!

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Maria Viola @mariafviola.bsky.social · Nov 16

Please please share your secrets on how you manage to get your gut immunos looking so gorgeous!

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Reposted by Maria Viola

Amy Engevik @amyengevik.bsky.social · Nov 16

My first #FluorescenceFriday post on BlueSky 😱.🤞 that this platform makes for a great space to share science.

#bioart #sciart #pathart #histoart #microscopy #intestine

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Maria Viola @mariafviola.bsky.social · Nov 16

Macrophage people, who’s going to be at #EMDS2024? I will be presenting a poster on our latest work on what all these microplastics are doing to our liver (spoiler alert: it’s BAD) and I’d love to connect to other people interested in #macrophages #gutimmunology

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