Lightnews — Scholar-powered news

markgerstein.bsky.social @markgerstein.bsky.social · 3h

Posting my talk tomorrow on AI in Biomedicine at
Einstein Med (hosted by @zhengdy.bsky.social)
lectures.gersteinlab.org/summary/AI-t... Using AI for brain genomics & thinking about how it can do this research autonomously. Lots of new slides on AI coding & risks

Reposted

DrDinD.bsky.social @drdind.bsky.social · 1d

🧵The Nobel Prize in Physics today went to John Clarke (UK), Michel Devoret (France), & John Martinis (USA) today for work conducted in Clarke's UC Berkeley lab in the mid 80s showing that alternation of a quantum state could proceed from one side to the other of a device you can see with your eye.

John Clarke, UC Berkeley Emeritus professor, Michel Devoret, Yale Emeritus Professor, and John Martinis, UC Santa Barbara Emeritus Professor, winners of the 2025 Nobel Prize in Physics.

2 30 98

Reposted

gersteinlab.bsky.social @gersteinlab.bsky.social · 16d

📚 Yale students have returned to campus, so time for a roster meeting!

We again made our Nobel Prize predictions (given how accurate we were last year 😉)

🥇Our top prediction is Habener & Knudsen (GLP-1) with 28.5% of the vote!
🥈 In second is Rothberg & David Klenerman (NGS)

1 1 1

markgerstein.bsky.social @markgerstein.bsky.social · Sep 6

Did my annual triathlon today in Madison. Good swim. Steady bike. Walk-skip-walk to the finish line. Made it! And, unlike last year, did an extensive stretch afterwards & drove myself home. Before & after race pics. (More at flickr.com/photos/mbgmb...)

2

Reposted

gersteinlab.bsky.social @gersteinlab.bsky.social · Aug 25

Curious how your favorite gene changes when and how during a biological process?
Want to dive into the kinetics of chromatin + gene expression?
Meet chronODE, our new tool to model multi-omic time-series with logistic equations + ML!
doi.org/10.1038/s414...

The chronODE framework for modelling multi-omic time series with ordinary differential equations and machine learning - Nature Communications

Here, the authors use a simple equation to study how genes and their regulators switch on/off over time, across the whole genome in tissues and cells. Most changes are gradual, but some genes switch q...

doi.org

1 2 2

markgerstein.bsky.social @markgerstein.bsky.social · Aug 18

Posting my talk on AI & Brain Disorders at Princeton CHDI on Tuesday lectures.gersteinlab.org/summary/Ext-... Lots of new slides on drug repurposing and predicting age from histology images

Reposted

gersteinlab.bsky.social @gersteinlab.bsky.social · Jul 14

🧠 At our recent Gerstein Lab roster meeting, we took a detour into… personality science!

Turns out we’re INT Central 🧪
📌 70% Introverts
📌 83% Intuitives
📌 57% Thinkers
Analysts (INTP, INTJ) dominate, far more than the U.S. baseline.

#MBTI #INTP #INTJ

1 1 1

markgerstein.bsky.social @markgerstein.bsky.social · Aug 2

Thoughts on Pearl's Book of Why blog.gerstein.info/2025/08/thou... Lots of Good Intuition on Bayesian Networks, Sometimes with Strong Opinions

Reposted

Eric Topol @erictopol.bsky.social · Jul 30

"The microplastic (MP) 1–10 μm exposure estimates are 100-fold higher than previous estimates that were extrapolated from larger MP sizes, and suggest that the health impacts of MP inhalation may be more substantial than we realize."
journals.plos.org/plosone/arti...

Human exposure to PM10 microplastics in indoor air

The ubiquitous presence of airborne microplastics (MPs) in different indoor environments prompts serious concerns about the degree to which we inhale these particles and their potential impact on huma...

journals.plos.org

6 40 120

markgerstein.bsky.social @markgerstein.bsky.social · Jul 30

Posting my talk tomorrow at @emblebi.bsky.social‬ (for the @ensembl.bsky.social‬ group) lectures.gersteinlab.org/summary/Expl... AI Approaches for Understanding Brain Disorders: Exploring Intermediate Endophenotypes connecting Genotype to Diseases

2

markgerstein.bsky.social @markgerstein.bsky.social · Jul 28

Posting my talk tomorrow at @geneticscam.bsky.social on AI for Brain Disorders lectures.gersteinlab.org/summary/Mode... Lots of new slides on characterizing brain developmental time series with sigmoids

2

markgerstein.bsky.social @markgerstein.bsky.social · Jul 19

Posting my talk on Mon. on Cancer Genomics at the Institut Curie lectures.gersteinlab.org/summary/Char... Lots of new slides on using LLMs for "tumor boards" & for generating genomics workflows

markgerstein.bsky.social @markgerstein.bsky.social · Jun 26

Posting my talk tomorrow at the AI4Chemistry Summit at NYU lectures.gersteinlab.org/summary/AI-f... Lots of new slides on computing small molecule Hamiltonians & predicting macromolecular misfolding

1

markgerstein.bsky.social @markgerstein.bsky.social · Jun 23

Posting my talk tomorrow at the SCORCH consortium meeting lectures.gersteinlab.org/summary/Chro... Tools for brain single-cell analysis: ChronODE for series data and ASTRO for spatial data.

Reposted

Yale MB&B @yalembb.bsky.social · Jun 9

Join us next week for MB&B's Computational Biophysics & Biochemistry Symposium on 6/17 in Bass 305!

2 2

markgerstein.bsky.social @markgerstein.bsky.social · Jun 9

Posting my talk tomorrow for the IMPACT-MH Consortium lectures.gersteinlab.org/summary/Digi... Digital Phenotyping from Wearables Using AI. Some new slides on using wearables to predict exercise lapses

markgerstein.bsky.social @markgerstein.bsky.social · Jun 7

Also, we've summarized our analysis of @carlzimmer.com's genome out to Chr22. And we have synced the lectures more closely with readings, now trying to reference the great ISL book as much as possible (statlearning.com)

markgerstein.bsky.social @markgerstein.bsky.social · Jun 7

School's out for the summer, & I've finally got around to cleaning up the website for my class on biomedical data science (gersteinlab.org/courses/452)
I've been teaching this course for >25 years. This year, we've posted lots of new lecture videos.

1

Reposted

Yale Ventures @yaleventures.bsky.social · May 8

📣 200+ Innovators Presenting at the 2025 Yale Innovation Summit 📣

Meet the founders who will compete for $300k in prizes during 6 live pitch sessions, interactive ePoster presentations, and virtual showcases at #YaleInnovation2025

👉 bit.ly/3GKJ0Mk

1 3

markgerstein.bsky.social @markgerstein.bsky.social · May 27

Liked the visual effect of @newyorker.com's recent "Double Cover"

markgerstein.bsky.social @markgerstein.bsky.social · May 14

Posting my talk tomorrow at the @broadinstitute.org's Stanley Center lectures.gersteinlab.org/summary/Expl... Exploring Intermediate Endophenotypes connecting Genotype to Diseases

Reposted

gersteinlab.bsky.social @gersteinlab.bsky.social · May 5

1/4 🚀 New #ICLR2025 SPOTLIGHT ALERT
Gerstein Lab presents “Enhancing the Scalability & Applicability of Kohn-Sham Hamiltonians”—led by YunyangLI & Z Xia & L Huang & J Zhang & @markgerstein.bsky.social . Joint work with @msftresearch.bsky.social .

1 1 2

markgerstein.bsky.social @markgerstein.bsky.social · May 6

Posting my talk today at
the @ucirvine.bsky.social center for Neural Circuit Mapping lectures.gersteinlab.org/summary/SCZ-... . Lots of slides on using AI approaches for Schizophrenia, Alzheimer's & ADHD, including some new ones on analyzing AD imaging.

markgerstein.bsky.social @markgerstein.bsky.social · May 4

Posting my talk on Mon. for the Frontiers in Computational Biosciences series at @UCLA lectures.gersteinlab.org/summary/Bett... . Lots of new slides on creating digital phenotypes from wearable devices & relating them to genetics and on quantum computing

Reposted

Paul Byrne @theplanetaryguy.bsky.social · Apr 29

This is a new image from #JWST.

The bright points with spikes are stars in the Milky Way.

Everything else is a galaxy.

Everything. Else. Is. A. Galaxy.

620 4K 19K