🧬🧬🧬 New review from the lab:

Evolution of comparative transcriptomics: biological scales, phylogenetic spans, and modeling frameworks

authors.elsevier.com/sd/article/S...

By @mattezambon.bsky.social & @fedemantica.bsky.social, together with @jonnyfrazer.bsky.social & Mafalda Dias.

@cwjpugh.bsky.social at #VariantEffect25

How can we improve gene regulatory network inference from noisy scRNA-seq data? Our new review in @molsystbiol.org explores the latest methods integrating prior knowledge to enhance reliability. Plus, some suggestions on how to improve benchmarking!
www.embopress.org/doi/full/10....

Art and science merged this afternoon in a wonderful concert from our fellow PhD candidate Matilda Pfeiffer toghether with the musician Clara Cantore in a performance reflecting on points of contact between music and science.
Couldn’t be more happy to be part of this phd community 💫
#CRGPhDSymp2024

A highly relevant talk from Nico Lorenzon describing novel diagnostic tools to assess treatment resistance in Mayor Depressive Disorder #CRGPhDSymp2024

Attending a fascinating talk by Khashayar Baghizadeh on data-driven computational modeling of the Dentate Gyrus in Down Syndrome. Great work integrating anatomical and physiological data to unravel underlying mechanisms.

#CRGPhDSymp2024

As the #CRGPhDSymp progresses, Leo Zuber gave an insightful talk on his research integrating spatial information with GWAS data for developing a spatially aware, tissue-specific genomic risk score, evaluated in the context of COVID-19 disease severity. 🦠🧬

Next up is Andrea Barrera! Presenting a fascinating talk which leaves us wondering, can metabolic intervention affect genome stability? #CRGPhDSymp2024

Kicking us off today is Tamara Perteghella from the Guigó lab with her talk on the latest release of #GENCODE, dramatically increasing the number of annotated lncRNAs. Well done to everyone involved in the consortium! #CRGPhDSymp2024

Sun is shining above PRBB for the second day of the 2024 PhD Symposium ☀️ I don’t think I’ll get tired anytime soon of sea’s view for my morning coffee 🤗 #CRGPhDSymp2024

Reporting from the #CRGPhDSymp2024 today and tomorrow! Kicking it off with a fascinating talk Gioia Quarantani on DMS of a 1000 exons to investigate alternative splicing

Very interesting talk from Pablo Lanuza about mechanistic understanding of splicing, titled SPF45 and 3'splice site proofreading.

#CRGPhDSymp2024 #splicing

Navigating the #CRGPhDSymp2024 poster session, I’m slowly becoming an expert at nodding thoughtfully while frantically trying to understand someone’s life work in 3 minutes!

Great talk from Javier Navarro Delgado on understanding, predicting and engineering variant effects in synthetic antibodies. #AntibodyDiscover #CRGPhDSymp2024

Great talk from Laia Montes Espuna at the @crg.eu PhD Symposium! Her work is focused on cell type diversity in early metazoans, aiming at broadening the understanding of cell type identity programs across the animal kingdom 🪸🧬 #CRGPhDSymp2024

Our amazing CRG PhD community are celebrating their annual symposium
today and tomorrow.

Follow our first year students on Bluesky for snippets about all the amazing talks featured this year:

@lassemiddendorf.bsky.social
@mattezambon.bsky.social
@iseultleahy.bsky.social

Big 🧬 news this week: we have launched the first Joint Program on Evolutionary Medical Genomics. Spearheaded by @mirimiam.bsky.social, Barcelona researchers will study and exploit the vast genomic diversity of life on Earth to enhance precision medicine. Full story in @elpais.com