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Matyas Bubna-Litic @matyasbl.bsky.social · 4d

That's such a great book cover

Reposted by Matyas Bubna-Litic

Maik Bischoff @maikbischoff.bsky.social · 14d

1/12 A very special moment for me! 🎉

My first paper as corresponding author—a @jcb.org Perspective on how contact-based decision-making in collective cell migration can itself encode blueprints for complex patterns and shapes.

rupress.org/jcb/article/...

#cellbio #devbio #science

🧵for details

Cartoon of a speculative heterogenous cell population performing mesenchymal collective cell migration.

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Matyas Bubna-Litic @matyasbl.bsky.social · 16d

Animal caps are back in fashion!

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Matyas Bubna-Litic @matyasbl.bsky.social · 16d

Pretty cool

kuba sędziński @kuba-sedzinski.bsky.social · 16d

🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x

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Reposted by Matyas Bubna-Litic

Alice Godden @alicegodden.bsky.social · 22d

Our new paper is out in Dev Biol! 🎉 🐸🧬
We show #miR-196a directs #neural crest fate in #Xenopus by repressing immature neural #ectoderm — evidence #miRNAs can potentially drive, not just fine-tune, early patterning
👉 Read more here: doi.org/10.1016/j.yd...
@devbiol.bsky.social @biouea.bsky.social

Schematic overview of our project. Dissection of Xenopus neural crest following morpholino knockdown of miRNA, then extraction of RNA for RNA-seq

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Reposted by Matyas Bubna-Litic

Society for Developmental Biology @socdevbio.bsky.social · 23d

Mouse (Mus musculus) 🐭 is the powerhouse of mammalian genetics, essential for studying embryogenesis, organ development and gene function using transgenic technologies. 📸 Image by Zhong Hua also featured on the cover of Developmental Biology textbook (11th edition) #ModelMonday

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Matyas Bubna-Litic @matyasbl.bsky.social · Sep 4

Thank you for sharing! I'd like to highlight the concept of embryonic 'actuation' where a mechanical state change is caused by cells acting on each other through mechanics and/or biochemical signals but importantly not mediated by fate transitions.

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Reposted by Matyas Bubna-Litic

Society for Developmental Biology @socdevbio.bsky.social · Aug 24

Got stunning fluorescence microscopy images? 🌈🔬 SDB wants to feature YOUR work for #FluorescenceFriday! We highlight images from SDB members with a short description and the image creators 📸. Fill out the form to be featured: docs.google.com/forms/d/e/1F...

Society for Developmental Biology @socdevbio.bsky.social · Aug 22

✨If Monet studied mouse ovaries 🎨 Stromal cells 💜 Follicular cells 🔵 and Fatty Cells 🟡. Together, they reveal the cellular architecture and functional zones of the ovary 🔬 Image provided by @shmimberly.bsky.social 🧪 #FluorescenceFriday #ReproductiveBiology

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Reposted by Matyas Bubna-Litic

Alex Fedorec @ajfedorec.bsky.social · Aug 13

I'm going to be advertising for a few positions in my group in the next couple of months for a big project on synthetic microbial communities.

I would love to hear from you if you are interested and I'd also appreciate if everyone could share this far and wide!

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Reposted by Matyas Bubna-Litic

Society for Developmental Biology @socdevbio.bsky.social · Aug 15

✨Not a rainbow trout… a rainbow zebrafish 🌈 🐟
The expression of 10 different genes simultaneously including Hox genes along the body axis, somites, brain regions, skeletal muscle, and heart 🔬Image by Alice Sherrard, Gabby Jerz & Nipam Patel 🧪 #FluorescenceFriday

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Reposted by Matyas Bubna-Litic

Society for Developmental Biology @socdevbio.bsky.social · Aug 12

🚨Only 4 days to apply!!!🚨Join the SDB SciComm Internship! Gain hands-on experience writing stories on the latest developmental biology discoveries🔬Connect with top mentors & earn $500 to attend the SDB Annual Meeting 🎉! 👉 www.sdbonline.org/science_comm... #SciComm #DevBio

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Reposted by Matyas Bubna-Litic

Karen J Liu @karenjliu.bsky.social · Aug 5

Dev biologists! 3-yr postdoc position at King's, collaboration with Trizzino lab @marcotrizzino.bsky.social modelling CHD3 neural crest. We are looking for postdocs with mad embryology skills @the-node.bsky.social #developmental @ccrb27.bsky.social

thenode.biologists.com/jobs/postdoc...

Postdoctoral Research Associate: Modelling Neural Crest Anomalies (mouse/human) - the Node

The Liu lab is looking for a postdoc with a love of embryos and developmental biology! This post is part of an MRC-funded collaboration between Karen Liu’s lab at King’s College London and Marco Trizz...

thenode.biologists.com

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Matyas Bubna-Litic @matyasbl.bsky.social · Aug 10

This worked for me:
155 mM NaCl, 10 mM Tris-HCl at pH 7.5, 50 mM NaBH4 > in refrigerator 2 days before use.

Use: After permeabilising apply AF-reducing agent overnight at 4˚C

It's possible to do it faster at room temp and higher NaBH4 conc but it's less gentle to the sample.

Hope it works!

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Matyas Bubna-Litic @matyasbl.bsky.social · Aug 10

Looks like an exciting meeting. Would you know if it's possible to attend online? Thanks

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Matyas Bubna-Litic @matyasbl.bsky.social · Aug 9

I'm not sure how bacteria on oysters are but in early Xenopus cells sodium borohydride works well to remove autofluorescence from sources like PFA fixation. There's a good protocol on CSH I can try look for it.

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Reposted by Matyas Bubna-Litic

Society for Developmental Biology @socdevbio.bsky.social · Aug 8

Got stunning fluorescence microscopy images? 🌈🔬 SDB wants to feature YOUR work for #FluorescenceFriday! We highlight images from SDB members with a short description and the image creators 📸. Fill out the form to be featured: docs.google.com/forms/d/e/1F...

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Reposted by Matyas Bubna-Litic

Young Embryologist Network @yen-network.bsky.social · Aug 9

Interesting review about the role of ECM in development!

Cells & Development @cellsdev.bsky.social · Aug 8

Maybe it's time we rethink the idea that development is a cell centric process? In this beautiful review, María-del-Carmen and @stramerlab.bsky.social discussed how the ECM underlies and influences many morphogenesis processes from wing unfolding to mammary gland development.
doi.org/10.1016/j.cd...

Tissue bending through localized BM growth or dissolution.

Alteration in tissue morphology by intrinsic stresses in an assembling BM network.

Branching morphogenesis driven by localized deposition of interstitial matrix.

Asymmetric tissue expansion through anisotropic BM remodeling.

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Reposted by Matyas Bubna-Litic

Nicoletta Petridou @nicolettapetridou.bsky.social · Aug 8

We are searching for an enthusiastic scientist to join our team and establish annual killifish as a model system for early developmental biology and biophysics! @embl.org @embldbunit.bsky.social

Apply here:
embl.wd103.myworkdayjobs.com/EMBL/job/Hei...

Please re-post 🙏

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Reposted by Matyas Bubna-Litic

Toby Andrews @tobyandrews.bsky.social · Aug 6

Thrilled to bits to see our latest work online in Dev Cell! 🥳

We wanted to know how cells build functional organs with precision🫀🫁📏 Here we show how coupling of cell shape and organ function fine tunes the form and contractile power of the developing #zebrafish heart 1/n

tinyurl.com/cell-stretch

Mechanochemical coupling of cell shape and organ function optimizes heart size and contractile efficiency in zebrafish

Andrews et al. demonstrate that multiscale feedback between mechanical and chemical cues builds a functional heart to support zebrafish embryonic life. Cell recruitment and organ-scale forces drive tr...

tinyurl.com

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Reposted by Matyas Bubna-Litic

Anaïs Bailles @anaisbailles.bsky.social · Aug 6

Very happy that the first article from my postdoc work in the Tomancak lab is now published @PNAS! www.pnas.org/doi/10.1073/.... We studied the self-organization of actin in aggregates made from Hydra cells. Thread below (1/9)

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Matyas Bubna-Litic @matyasbl.bsky.social · Aug 6

Based on 'Tracing the genetic footprints of vertebrate landing in non-teleost ray-finned fishes' by Bi et al 2021

Matyas Bubna-Litic @matyasbl.bsky.social · Aug 6

I was looking for a diagram like this which shows some vertebrates with estimates of evolutionary divergence between groups. I found one by Bi et al. 2021 published in Cell but it was too complicated. I ended up making this. What other diagrams do you find useful to show our evolutionary history?

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Matyas Bubna-Litic @matyasbl.bsky.social · Aug 6

It therefore makes sense to me that what we generally call ‘fish’ should be termed ‘non-tetrapod bony fish’ which excludes land-dwelling four-legged animals like mammals (including whales) and reptiles as well as sharks.

Matyas Bubna-Litic @matyasbl.bsky.social · Aug 6

People have started to accept the scientific view that birds have descended from dinosaurs and there is no way to group dinosaurs without including the bird lineage. Therefore, we now often refer to the extinct species of lizard-like animals who dominated the Mesozoic Era as ‘non-avian dinosaurs’.

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Matyas Bubna-Litic @matyasbl.bsky.social · Aug 6

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