Lightnews — Scholar-powered news

Reposted by Mike Morgan

Zamin Iqbal @zaminiqbal.bsky.social · Apr 29

Small update from AllTheBacteria (allthebacteria.org). Assemblies can be bulk downloaded from OSF as before, or you can now get individual assemblies from AWS. We now also have a LexicMap index on AWS, so you can align your favourite gene against 2.4million bacteria (next post for price estimates)

AllTheBacteria

allthebacteria.org

1 23 47

Mike Morgan @mdmorgan.bsky.social · Apr 30

On an immunological note, promiscuous expression of reproductive tissue antigens in the thymus might also suggest there is a need for tolerance against these tissues, albeit earlier in life than most cancer patients. What are your thoughts?

1

Mike Morgan @mdmorgan.bsky.social · Apr 30

Baking in marginal selection of antigens to prevent the adverse loss of reproduction seems a minor inconvenience compared to stopping someone from having kids full stop.

3 1

Mike Morgan @mdmorgan.bsky.social · Apr 30

Saying reproductive tissues are fair game relegates the patient to an object rather than a living breathing person. If that cancer therapy destroys someone's child bearing or producing capacity that is not a good therapy.

2

Mike Morgan @mdmorgan.bsky.social · Apr 30

Intriguing - maybe worth throwing into the mix that CTAs might need to be sex dependent. Probably not a great idea to give anti-testes CARTs to blokes and anti-placental CARTs to women.

1

Reposted by Mike Morgan

British Society for Immunology @britsocimm.bsky.social · Apr 29

Celebrate International #DayofImmunology by treating yourself to one of our events or training courses! 🎉

Whether its our Diversity in Immunology event, next week’s Flow Cytometry training, or the BSI Immunology Awards - there's something for you 👀 bit.ly/3v2aAi1

4 5

Reposted by Mike Morgan

Viki Male @vikilovesfacs.bsky.social · Apr 24

👶🏼 Many #vaccines are not effective in newborns. So how do we protect them from infectious disease?

🤰🏽 By vaccination in #pregnancy!

Here we review…

💉 Established campaigns vs whooping cough, flu, COVID

💡 New approaches to RSV, GBS

🌈 Future challenges, opportunities

#ReproSky #ImmunoSky #IDSky

Vaccination in pregnancy to protect the newborn - Nature Reviews Immunology

In this Review, Male and Jones provide an overview of the current vaccines that are offered during pregnancy and to newborns, explaining the rationale behind the different vaccination programmes and t...

www.nature.com

4 120 270

Reposted by Mike Morgan

British Society for Immunology @britsocimm.bsky.social · Apr 24

Today marks the start of #WorldImmunisationWeek! ⭐

Get inspired by reading our latest #CelebrateVaccines blog, which explores how the new RSV vaccine is cutting NHS costs and protecting vulnerable populations.

🔗 bit.ly/42V1NwZ

#VaccinesWork #HumanlyPossible

7 5

Reposted by Mike Morgan

Matthew Cobb @matthewcobb.bsky.social · Apr 12

Jess read the “dire wolf” preprint so you don’t have to. A long, exasperated and heroic evening thread by someone who knows what they are talking about, which shows the whole thing to be even more flakey than we thought. We salute you, @jfmclaughlin92.bsky.social!

Jess McLaughlin, PhD (they/them) @jfmclaughlin92.bsky.social · Apr 12

alright i have my laptop, guess i'm livetweeting the dire wolf preprint.

so a quick reminder: this is not yet peer-reviewed, so there's some different expectations re: quality.

also let's be clear, i'm a hella biased reader, bc i don't trust the hype they're courting

Jess McLaughlin, PhD (they/them) @jfmclaughlin92.bsky.social · Apr 12

Briefly read through this and...hmm. I have thoughts that may merit a deeper dive.

One big concern: while their reference method seems reasonable for research uses, I'm thinking that if you want to claim you're cloning one, I'm sorry but you've actually gotta de novo that.

14 27

Reposted by Mike Morgan

Ardem Patapoutian @ardemp.bskyverified.social · Apr 9

Published an op-ed for @cnn.com: “Nobel laureate: I owe America my success. Today, its scientific future is in danger.”
A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...

Nobel laureate: I owe America my success. Today, its scientific future is in danger | CNN

Dr. Ardem Patapoutian says he watches “with deep sadness as the United States’ remarkable scientific enterprise, which took generations of hard work and national investment to build, faces a concerted...

www.cnn.com

15 490 900

Reposted by Mike Morgan

bioRxiv Immunology @biorxiv-immuno.bsky.social · Mar 25

Anti-citrullinated protein antibodies arise during affinity maturation of germline antibodies to carbamylated proteins in rheumatoid arthritis https://www.biorxiv.org/content/10.1101/2025.03.22.644346v1

1 2

Reposted by Mike Morgan

European Conference on Computational Biology @eccb-europe.bsky.social · Mar 25

📆 Mark your agenda for the 25th European Conference on Computational Biology! It will take place in Geneva, Switzerland, from 31 August-4 September 2026.

👉 Save the date and stay tuned for more updates as we get ready for #eccb2026

8 10

Reposted by Mike Morgan

Darragh Duffy @darraghduffy.bsky.social · Mar 24

13 chair positions open @inserm.fr to lead a junior research group in France covering #neuroscience, #immunology, #bioinformatics, #bioengineering, #biotherapy, #public health pro.inserm.fr/rubriques/co... 🧪🔬

pro.inserm.fr

2 43 36

Reposted by Mike Morgan

Saez-Rodriguez Group @saezlab.bsky.social · Mar 17

6 days left to apply to the Post-doc opening in our lab
@ebi.embl.org to develop&apply #bioinformatics & #machine-learning methods to study intra-/extra cellular networks to extract disease mechanisms from #single-cell and #spatial multiomic data: embl.wd103.myworkdayjobs.com/EMBL/job/Hin...

Postdoctoral fellow - Saez-Rodriguez Group

Your group Saez-Rodriguez Research Group Your supervisor Julio Saez-Rodriguez Your role As a postdoctoral fellow in the Saez Rodriguez group, you will develop and apply computational methods and tools...

embl.wd103.myworkdayjobs.com

1 27 31

Reposted by Mike Morgan

Alper Akay @alperakay.bsky.social · Mar 16

We are advertising for a PhD position to study bacterial metabolites in C. elegans, funded by the MRC Microbes, Microbiomes and Bioinformatics training programme @uniofeastanglia.bsky.social @biouea.bsky.social. Open to UK and international students. www.findaphd.com/phds/project...

Uncovering bacterial metabolites that can attenuate vitamin B12 deficiency (AKAY_U25MMB) at University of East Anglia on FindAPhD.com

PhD Project - Uncovering bacterial metabolites that can attenuate vitamin B12 deficiency (AKAY_U25MMB) at University of East Anglia, listed on FindAPhD.com

www.findaphd.com

1 22 14

Reposted by Mike Morgan

Christian Moore-Anderson @cmooreanderson.bsky.social · Mar 12

Today I taught about phenylketonuria and eugenics. An important lesson, especially in times of nazis. Blog post:
#iTeachBio #SciTeachUK

cmooreanderson.wixsite.com/teachingbiol...

How I teach the monogenic disorder PKU with a model and some history of eugenics

If you're teaching Mendelian genetics, monogenic disorders are on the cards. But which ones are good examples? The IB has once again decided on PKU (phenylketonuria). In this post, I'll show you how ...

cmooreanderson.wixsite.com

1 2 4

Reposted by Mike Morgan

Dr Emma Hodcroft @firefoxx66.bsky.social · Mar 12

Great article from Ewen Callaway in @nature.com about how #SARSCoV2 has helped us better understand viruses - including the areas where we still have much to learn.

“This was one of the first times where evolutionary biology became an applied science” says @jbloomlab.bsky.social

Four ways COVID changed virology: lessons from the most sequenced virus of all time

After 150,000 articles and 17 million genome sequences, what has science taught us about SARS-CoV-2?

www.nature.com

4 40 110

Reposted by Mike Morgan

Aylwyn Scally @aylwyn-scally.bsky.social · Feb 21

We are excited to announce a new faculty position here in Cambridge, for researchers in computational and/or theoretical biology, based jointly in Genetics and Mathematics. Come and join us! Happy to answer questions about research, teaching and working here. www.jobs.cam.ac.uk/job/50414/

Assistant/Associate Professor in Computational Biology - Job Opportunities - University of Cambridge

Assistant/Associate Professor in Computational Biology in the Department of Applied Mathematics and Theoretical Physics at the University of Cambridge.

www.jobs.cam.ac.uk

5 240 310

Reposted by Mike Morgan

Babraham Bioinformatics @babraham-bioinf.bsky.social · Mar 10

Exploring #Proteomics?
Join us for a brand new and improved *Analysing Proteomics Data* #bioinformatics #training course this Wednesday 12th March, live online via Zoom
9:30-17:00 GMT/UTC
www.bioinformatics.babraham.ac.uk/training.html

a man is typing on a keyboard in a living room

Alt: a man is typing on a keyboard in a living room

media.tenor.com

4 10

Reposted by Mike Morgan

Adam Rutherford @adamrutherford.bsky.social · Mar 6

A mammoth circus of macabre fantasy and moral bankruptcy.
I got my views on mammoths down. Enjoy.

www.theguardian.com/commentisfre...

Reviving the woolly mammoth isn’t just unethical. It’s impossible | Adam Rutherford

At a time when US scientists are under attack from their own government, the illiteracy around these elephantine fantasies is dangerous, says geneticist Adam Rutherford

www.theguardian.com

36 190 540

Reposted by Mike Morgan

Nonia Pariente @npariente.bsky.social · Mar 9

📣📣Are you looking for a postdoc? 📣📣

Does a EU or Horizon Europe assoc country (eg UK, S Korea) seem like a good destination?

These fellowships a great funding option for anyone in the 🌎

👀 Check them out - next call opens 8 May

🧪 👨‍🔬👩‍🔬
marie-sklodowska-curie-actions.ec.europa.eu/actions/post...

Postdoctoral Fellowships

The information provided on this page is a summary of the main rules and requirements for Postdoctoral Fellowships (PFs) and who can apply for them.

marie-sklodowska-curie-actions.ec.europa.eu

5 130 220

Reposted by Mike Morgan

Wolfgang Huber @wkhuber.bsky.social · Nov 22

Join the Interdisciplinary Postdoc Fellowship Program at the European Molecular Biology Laboratory (EMBL), one of the best places to do research in modern biology and develop your career.

Great opportunities for statisticians, comp. biologists, AI experts, mathem. modelers!
www.embl.org/eipod-linc

32 41

Reposted by Mike Morgan

Daniel Seaton @danieldseaton.bsky.social · Mar 6

Are you a postgraduate student interested in protein modelling and drug discovery?

We have an exciting opportunity to join our team at GSK for a 6-9 months internship, working on an ambitious cross-department research project. Apply before March 14th!

www.linkedin.com/jobs/view/41...

GSK hiring Computational Biologist in Stevenage, England, United Kingdom | LinkedIn

Posted 11:13:48 PM. Site Name: UK - Hertfordshire - Stevenage, Heidelberg - OfficePosted Date: Feb 28 2025We create a…See this and similar jobs on LinkedIn.

www.linkedin.com

1 7 6

Reposted by Mike Morgan

Justin Barton @jbarton.bsky.social · Mar 3

The IMMREP25 TCR specificity prediction challenge is now live on Kaggle!

Get involved: kaggle.com/competitions...

Huge thanks to: Matthew Noakes, @the-dee-em.bsky.social, @everichardson.bsky.social, @bjoernpeters.bsky.social , @adaptivebiotech.bsky.social , IEDB, @airr-community.bsky.social

IMMREP25: TCR Specificity Prediction Challenge

Competitors will make predictions on previously unpublished TCR-epitope binding data in order to benchmark prediction methods.

kaggle.com

10 11

Mike Morgan @mdmorgan.bsky.social · Mar 2

PubMed has not been disappeared. It's working fine 👇🏼

1