Mike Clark
@michaelbclark.bsky.social
Genetics, transcriptomics, RNA and neuroscience.
Lab head at the University of Melbourne, Australia.
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Lab head at the University of Melbourne, Australia.
View own.
Reposted by Mike Clark
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Australian Science & Biomedical Research in Crisis
Please use this form to share the impact of Australia's historically low success rates for major competitive research grants on your research, your team, and your mental health.
Researchers do researc...
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December 1, 2025 at 2:17 PM
Share your stories here docs.google.com/forms/d/e/1F... #SaveOzScience
Hard to know for sure until NHMRC releases funding details. From the grants I reviewed I think requested funds have increased as cost of research has gone up. Clearly funding available hasn't kept pace to even maintain the poor success rate we previously had.
November 26, 2025 at 9:45 PM
Hard to know for sure until NHMRC releases funding details. From the grants I reviewed I think requested funds have increased as cost of research has gone up. Clearly funding available hasn't kept pace to even maintain the poor success rate we previously had.
It's an all time low in both the percentage and number of #NHMRC #IdeasGrant funded. Previous lowest percentage was 9.8% in the 2020. However 283 grants were funded that year, this year it's under 200.
November 26, 2025 at 10:50 AM
It's an all time low in both the percentage and number of #NHMRC #IdeasGrant funded. Previous lowest percentage was 9.8% in the 2020. However 283 grants were funded that year, this year it's under 200.
Individual outcomes aren't publicly released yet, but all applicants have been told if they were successful or not
November 26, 2025 at 10:41 AM
Individual outcomes aren't publicly released yet, but all applicants have been told if they were successful or not
This project was led by the talented @jakobschuster.bsky.social in colab with @qgouil.bsky.social & @mritchieau.bsky.social
As an example of the power of Matchbox, Jakob’s last tool was Restrander. A 17 line matchbox script achieved the same result as 1400 lines of C++ in Restrander!
As an example of the power of Matchbox, Jakob’s last tool was Restrander. A 17 line matchbox script achieved the same result as 1400 lines of C++ in Restrander!
November 26, 2025 at 2:03 AM
This project was led by the talented @jakobschuster.bsky.social in colab with @qgouil.bsky.social & @mritchieau.bsky.social
As an example of the power of Matchbox, Jakob’s last tool was Restrander. A 17 line matchbox script achieved the same result as 1400 lines of C++ in Restrander!
As an example of the power of Matchbox, Jakob’s last tool was Restrander. A 17 line matchbox script achieved the same result as 1400 lines of C++ in Restrander!
We’ve demonstrated Matchbox for demultiplexing long-read scRNA-seq data with 10X or SPLiT-seq barcodes; restranding RNA-seq reads; assessing CRISPR editing efficiency; and haplotyping repeat regions.
Matchbox is implemented in rust and available from github.com/jakob-schust....
Matchbox is implemented in rust and available from github.com/jakob-schust....
November 26, 2025 at 2:03 AM
We’ve demonstrated Matchbox for demultiplexing long-read scRNA-seq data with 10X or SPLiT-seq barcodes; restranding RNA-seq reads; assessing CRISPR editing efficiency; and haplotyping repeat regions.
Matchbox is implemented in rust and available from github.com/jakob-schust....
Matchbox is implemented in rust and available from github.com/jakob-schust....
Agreed. And thanks for giving such a clear and engaging talk. Not my field but I definitely learnt a few things.
November 25, 2025 at 1:45 PM
Agreed. And thanks for giving such a clear and engaging talk. Not my field but I definitely learnt a few things.