Michael Haichin
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michaelhaichin.bsky.social
Michael Haichin
@michaelhaichin.bsky.social
Basketball & drugs enthusiast. Pronounced "hi-kin"
Medical Advisor for @psychedelicalpha.bsky.social
Next-gen neuroplastogen developers be like
July 3, 2025 at 9:33 PM
“Approval rates significantly declined from 2022 to 2024 [...] In 2022, 74 of the 90 (82%) requests were approved, followed by 123 out of 165 (74.5%) in 2023 and 107 out of 181 (59.1%) in 2024, even though the number of overall requests remained stable.”

www.nature.com/articles/s44...
June 28, 2025 at 6:13 PM
This Is Your Priest on Drugs?
June 8, 2025 at 3:57 PM
Reposted by Michael Haichin
One of my favorite resources & collaborative opportunities for those interested in the psychedelic field!!

Amazing work!!
May 14, 2025 at 1:20 PM
Reposted by Michael Haichin
3 of my papers (2 preprints) made the list! Great resource and great for scoping out all that was published last year
May 14, 2025 at 1:31 PM
Reposted by Michael Haichin
📚✨ ~500 Papers. ~30 Researchers & Experts. One Annotated Psychedelics Bibliography...

Very excited to share the 2024 edition of Psychedelic Alpha's Interdisciplinary Annotated Psychedelic Research Bibliography, by @michaelhaichin.bsky.social.

psychedelicalpha.com/news/the-int...
The Interdisciplinary Annotated Psychedelic Research Bibliography of 2024 - Psychedelic Alpha
Psychedelic Alpha’s Medical Advisor, Michael Haichin, compiled a list of over 500 notable psychedelics-related publications from 2024. He then presented it to a group of researchers from varying…
psychedelicalpha.com
May 14, 2025 at 1:15 PM
Reposted by Michael Haichin
Got interviewed by the Microdose newsletter on the intersection of #psychedelic and #placebo research and on why psychedelic research should revisit the long forgotten Zelen design to solve the "know-cebo" problem. Enjoy!

themicrodose.substack.com/p/the-power-...
The power of “know-cebo”: 5 Questions for data scientist Balázs Szigeti
Szigeti discusses expectancy effects, unblinding, and how researchers might design better studies on psychedelics.
themicrodose.substack.com
March 26, 2025 at 6:32 AM
Reposted by Michael Haichin
Our new review in JAMA Psychiatry: "Expectancy Effects, Failure of Blinding Integrity, and Placebo Response in Trials of Treatments for Psychiatric Disorders"

jamanetwork.com/journals/jam...

Thanks to co-first author Guil Fusetto-Veronesi; and to Samuele Cortese, David Baldwin, Matt Garner

🧵👇
Expectancy Effects, Blinding Integrity, and Placebo Response in Psychiatric Disorders
This narrative review discusses the impact of expectancy effects and functional unblinding on treatment responses in randomized clinical trials of treatments in psychiatry.
jamanetwork.com
March 12, 2025 at 5:00 PM
Reposted by Michael Haichin
New: The Q1'25 Edition of our Psychedelic Drug Development Pipeline Bullseye Chart is now available to download.

Get an overview of psychedelic candidates by molecule type and phase of development via this handy visual.

psychedelicalpha.com/news/q125-ps...
Q1’25 Psychedelic Drug Development Pipeline: Bullseye Chart - Psychedelic Alpha
We present the psychedelic drug development pipeline in a ‘bullseye chart’ format, as of Q1’25.
psychedelicalpha.com
January 30, 2025 at 3:07 PM
Reposted by Michael Haichin
Psychedelic mental health research is booming—but how do we keep up with rapidly evolving evidence? 🌱 Our team proposes a living evidence synthesis approach to ensure clinicians, policymakers, and the public have access to the latest, most reliable data.
🔗 www.nature.com/articles/s44...
🧪🧵
An initiative for living evidence synthesis in clinical psychedelic research - Nature Mental Health
Renewed interest in psychedelics as treatments for mental disorders has recently emerged, but substantial challenges remain in obtaining evidence from available data to inform clinical decision-making...
www.nature.com
January 10, 2025 at 4:12 PM
5x5 for 2024

What were your 5 favourite albums, books, movies, podcasts, and TV shows this year?

See below for mine, in no particular order.

Quote this post and tell me yours!
December 29, 2024 at 9:10 PM
"Navigating this new world will require a more precise understanding of the psychoactive substances that are now part of it. Instead of attempting to sort chemical compounds into good and bad, we could pay more attention to how people use them." - @mikejay.bsky.social
www.nytimes.com/2024/12/23/o...
Opinion | As Drug Culture Becomes Mainstream, Our Language Needs To Evolve. (Gift Article)
We need a new language to talk about the chemicals and plants that change our consciousness.
www.nytimes.com
December 23, 2024 at 2:01 PM
Thought-provoking chapter about the integration of psychedelics into society: academic.oup.com/book/58175/c...

TL;DR 10-year trial period privately funded w/ a new type of insurance and only two doses of psilocybin per year per adult available in protected spaces following psychiatric screening.
December 22, 2024 at 9:45 PM
Reposted by Michael Haichin
I spoke with Javier Muniz, MD, who just left his role as Associate Director at FDA's Division of Psychiatry, about all things psychedelics.

psychedelicalpha.com/news/inside-...
Inside the FDA’s Psychedelics Journey: Javier Muniz, MD on Breakthroughs, Challenges, and the Future of the Field - Psychedelic Alpha
In our latest Pα+ interview, our Editor Josh Hardman speaks with Javier Muniz, MD, who recently left his post as Associate Director at the FDA’s Division of Psychiatry. In that role, Muniz was at the…
psychedelicalpha.com
December 5, 2024 at 4:11 PM
Another NMDA antagonist for depression bites the dust…
Is it still a viable target?
December 4, 2024 at 4:57 PM
Reposted by Michael Haichin
New paper! This was a fun lil collaboration with Maastricht University in which we thought we might find evidence that ayahuasca would increase false memory in an observational study. WRONG! Ended up enhancing memory (but read 'til end for caveats)
journals.sagepub.com/doi/10.1177/...
1/8
Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
journals.sagepub.com
December 2, 2024 at 8:36 PM
Reposted by Michael Haichin
Psychoactive-controlled ketamine for OCD study
doi.org/10.1177/0269...
"We did not assess blinding...prominent differences in dissociation scores...suggest that fentanyl 50 μg also did not provide an adequate blind...would not recommend its use (but do not have a suitable alternative to recommend)."
Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
doi.org
December 1, 2024 at 5:51 AM
Psychoactive-controlled ketamine for OCD study
doi.org/10.1177/0269...
"We did not assess blinding...prominent differences in dissociation scores...suggest that fentanyl 50 μg also did not provide an adequate blind...would not recommend its use (but do not have a suitable alternative to recommend)."
Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
doi.org
December 1, 2024 at 5:51 AM
Reposted by Michael Haichin
Benjamin Labatut is one of the most amazing writers I’ve ever read!

If you haven’t, please check “The day we ceased to understand the world” and “Maniac”

His interviews are also mind blowing:
youtu.be/E-OFnHwuTBg?...
"Anything that comes out of a writer is fiction." | Writer Benjamín Labatut | Louisiana Channel
YouTube video by Louisiana Channel
youtu.be
November 23, 2024 at 1:15 PM
Reposted by Michael Haichin
A new preprint for my new BlueSky homies: "Major life changes following psychedelic use: A retrospective survey among people using psychedelics naturalistically"
www.researchgate.net/publication/...
(PDF) Major life changes following psychedelic use: A retrospective survey among people using psychedelics naturalistically
PDF | Background: Psychedelic drugs show promise in facilitating a variety of long-term psychological changes, but they may also lead to unexpected... | Find, read and cite all the research you need o...
www.researchgate.net
November 20, 2024 at 5:55 PM
Reposted by Michael Haichin
I don't know who made this #psychedelics paper one but I love it so much I framed a copy for my office
November 19, 2024 at 5:58 AM
Hi 🦋
1) Medical Advisor to Psychedelic Alpha

2) 2024 Interdisciplinary Annotated Psychedelic Research Bibliography (psychedelicalpha.com/news/2023-an...) - let me know if you'd like to participate

3) Just finished There's Always This Year - the most beautifully written non-fiction I've come across
November 16, 2024 at 10:50 PM