Simon Michaeli
@michaelilab.bsky.social
Plant and cell biologist. Interested in 🔬 organelles, membrane trafficking, autophagy, 🌿🍂 senescence, 🍑 ripening, learning, teaching and much more 🪐
https://www.michaelilab.com/
https://www.michaelilab.com/
When the localization of a protein you thought you know well still manages to surprise you... 😯🤔☘️
#fluorescenceFriday by postdoctoral fellow Dr. Hala Khamesa-Israelov @volcaniinstitute.bsky.social
#fluorescenceFriday by postdoctoral fellow Dr. Hala Khamesa-Israelov @volcaniinstitute.bsky.social
December 12, 2025 at 10:19 AM
When the localization of a protein you thought you know well still manages to surprise you... 😯🤔☘️
#fluorescenceFriday by postdoctoral fellow Dr. Hala Khamesa-Israelov @volcaniinstitute.bsky.social
#fluorescenceFriday by postdoctoral fellow Dr. Hala Khamesa-Israelov @volcaniinstitute.bsky.social
In between some excellent talks, mostly from PhD students and postdocs (including our Dr. Pradeep Kumar Pathak 👇) and even one brave MSc student 👏🏻
December 5, 2025 at 10:00 AM
In between some excellent talks, mostly from PhD students and postdocs (including our Dr. Pradeep Kumar Pathak 👇) and even one brave MSc student 👏🏻
Was fabulous at the Israeli Society of ☘️ Sciences (ISPS) 2025 conf. held at Sde Boker @bengurionuni.bsky.social.
It started with an In Memoriam lecture by @taw-lab.bsky.social dedicated to the Late Prof Gad Galili and ended with best poster 🏆 awarded to Dr. Hala Khamesa-Israelov from our group!
It started with an In Memoriam lecture by @taw-lab.bsky.social dedicated to the Late Prof Gad Galili and ended with best poster 🏆 awarded to Dr. Hala Khamesa-Israelov from our group!
December 5, 2025 at 9:54 AM
Was fabulous at the Israeli Society of ☘️ Sciences (ISPS) 2025 conf. held at Sde Boker @bengurionuni.bsky.social.
It started with an In Memoriam lecture by @taw-lab.bsky.social dedicated to the Late Prof Gad Galili and ended with best poster 🏆 awarded to Dr. Hala Khamesa-Israelov from our group!
It started with an In Memoriam lecture by @taw-lab.bsky.social dedicated to the Late Prof Gad Galili and ended with best poster 🏆 awarded to Dr. Hala Khamesa-Israelov from our group!
My November....
Fun as well as troubling
Fun as well as troubling
November 22, 2025 at 1:16 PM
My November....
Fun as well as troubling
Fun as well as troubling
A short #research highlight on the intriguing, complex and potentially dual role of #autophagy in fruit ripening:
#plantscience
rdcu.be/eOY3h
#plantscience
rdcu.be/eOY3h
November 10, 2025 at 1:06 PM
A short #research highlight on the intriguing, complex and potentially dual role of #autophagy in fruit ripening:
#plantscience
rdcu.be/eOY3h
#plantscience
rdcu.be/eOY3h
A bit more of my Chengdu experience
October 23, 2025 at 7:04 AM
A bit more of my Chengdu experience
Probably the best urinal point in the world...
Tanglang mountain in Shenzhen
Tanglang mountain in Shenzhen
October 22, 2025 at 7:27 AM
Probably the best urinal point in the world...
Tanglang mountain in Shenzhen
Tanglang mountain in Shenzhen
How you say you're in a conference in Chengdu without saying you're in a conference in Chengdu...
October 14, 2025 at 6:56 AM
How you say you're in a conference in Chengdu without saying you're in a conference in Chengdu...
Hearing the good news from my country while in Chengdu. Much nicer to start the symposium on the plant hormone #ethylene tomorrow under these circumstances 🎉
October 13, 2025 at 12:00 PM
Hearing the good news from my country while in Chengdu. Much nicer to start the symposium on the plant hormone #ethylene tomorrow under these circumstances 🎉
Yes, everything as usual now...
June 28, 2025 at 10:50 AM
Yes, everything as usual now...
June 11, 2025 at 3:40 PM
June 10, 2025 at 11:02 AM
Even now, in these troubling times, Israel is still the only country in the Middle-East that marks and celebrates #PRIDEmonth. Wishing Queer Jews, Muslims, Christians, Druze, Atheists and all others in Israel, the M-E and beyond the best, and better days ahead. Remember, we're not our government!
June 8, 2025 at 8:31 AM
Even now, in these troubling times, Israel is still the only country in the Middle-East that marks and celebrates #PRIDEmonth. Wishing Queer Jews, Muslims, Christians, Druze, Atheists and all others in Israel, the M-E and beyond the best, and better days ahead. Remember, we're not our government!
Beautiful Rhodes 🇬🇷
May 17, 2025 at 7:35 AM
Beautiful Rhodes 🇬🇷
3. ACC and ethylene induce autophagy activity
May 9, 2025 at 12:00 PM
3. ACC and ethylene induce autophagy activity
2. They are more sensitive to ACC (ethylene's precursor)
May 9, 2025 at 12:00 PM
2. They are more sensitive to ACC (ethylene's precursor)
We were still skeptical about the ethylene direction until we realized the autophagy impact on ethylene may be broader, beyond ripening.
1. ATG5, ATG2, and ATG7 Arabidopsis mutants produce more ethylene than WT seedlings.
1. ATG5, ATG2, and ATG7 Arabidopsis mutants produce more ethylene than WT seedlings.
May 9, 2025 at 12:00 PM
We were still skeptical about the ethylene direction until we realized the autophagy impact on ethylene may be broader, beyond ripening.
1. ATG5, ATG2, and ATG7 Arabidopsis mutants produce more ethylene than WT seedlings.
1. ATG5, ATG2, and ATG7 Arabidopsis mutants produce more ethylene than WT seedlings.
One of the coolest things we saw was that fruits deficient in different ripening genes (upstream or downstream of ethylene) show different autophagy activity.
May 9, 2025 at 12:00 PM
One of the coolest things we saw was that fruits deficient in different ripening genes (upstream or downstream of ethylene) show different autophagy activity.
But what about ethylene? Its production from ATG4-silenced fruits started climbing a few days before wild-type fruits. Then, when we applied 1-MCP, an ethylene antagonist, we saw the mutants behave as the WT.
May 9, 2025 at 12:00 PM
But what about ethylene? Its production from ATG4-silenced fruits started climbing a few days before wild-type fruits. Then, when we applied 1-MCP, an ethylene antagonist, we saw the mutants behave as the WT.
This, together with another approach (Virus-Induced gene silencing of other ATG genes), revealed that autophagy restricts ripening. This was surprising to us, as it was in contrast to other previous reports in climacteric and nonclimacteric fruits.
May 9, 2025 at 12:00 PM
This, together with another approach (Virus-Induced gene silencing of other ATG genes), revealed that autophagy restricts ripening. This was surprising to us, as it was in contrast to other previous reports in climacteric and nonclimacteric fruits.
1st, we analyzed autophagy's activity and saw that it's increasing along ripening from essentially 0 when fruits are mature green up to impressive activity at mid the process. The collaboration from @suaybuestuen.bsky.social and former lab members
@zmbp-tuebingen.bsky.social helped a lot. Thanks!
@zmbp-tuebingen.bsky.social helped a lot. Thanks!
May 9, 2025 at 12:00 PM
1st, we analyzed autophagy's activity and saw that it's increasing along ripening from essentially 0 when fruits are mature green up to impressive activity at mid the process. The collaboration from @suaybuestuen.bsky.social and former lab members
@zmbp-tuebingen.bsky.social helped a lot. Thanks!
@zmbp-tuebingen.bsky.social helped a lot. Thanks!