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Reposted by Simon Michaeli

eLife @elife.bsky.social · 8d

Inside a thylakoid membrane

The molecular architecture of the thylakoid membrane in a vascular plant has been determined with single-molecule precision.
buff.ly/U9TzrOh

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Reposted by Simon Michaeli

Yasin Dagdas @plantophagy.bsky.social · 8d

Congrats Dr. A. Abdrakhmanov for a fantastic PhD defence @vbcscitraining.bsky.social @gmivienna.bsky.social ! I am proud of you👏

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Simon Michaeli @michaelilab.bsky.social · 16d

👉Clathrin-coated vesicles are targeted for selective autophagy during osmotic stress

www.biorxiv.org/content/bior...

#autophagy

Clathrin-coated vesicles are targeted for selective autophagy during osmotic stress

Plants experience hyperosmotic stress due to drought and salinity. This causes cellular water loss, decreases turgor pressure, and reduces cell volume. Osmotic stress affects plasma membrane tension, ...

www.biorxiv.org

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Simon Michaeli @michaelilab.bsky.social · Aug 26

Highly specific intracellular ubiquitination of a small molecule

www.nature.com/articles/s41...

Highly specific intracellular ubiquitination of a small molecule - Nature Chemical Biology

Li et al. discovered that the cytotoxic synthetic small molecule BRD1732 is directly ubiquitinated in cells. Ubiquitination of BRD1732 is E3 ligase dependent and leads to inhibition of proteasomal deg...

www.nature.com

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Reposted by Simon Michaeli

Team Thomma @teamthomma.bsky.social · Aug 15

📣 Massively proud of this ⬇️ great study, led by the brilliant @mesny.bsky.social surprisingly uncovering that many pathogen effectors stem from ancient antimicrobials 🤯 #EffectorWisdom #EvoMPMI

Fantin Mesny @mesny.bsky.social · Aug 15

📣 NEW PREPRINT 📝

We identified evolutionary origins of many fungal effectors!
We show that fungi secrete lots of antimicrobial proteins, and that some of them were repurposed by plant pathogens for host immune suppression.
www.biorxiv.org/content/10.1...

cc @teamthomma.bsky.social

Plant-associated fungi co-opt ancient antimicrobials for host manipulation

Evolutionary histories of effector proteins secreted by fungal pathogens to mediate plant colonization remain largely elusive. While most functionally characterized effectors modulate plant immunity, ...

www.biorxiv.org

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Simon Michaeli @michaelilab.bsky.social · Aug 16

What's going on today?
A flow of new cool publications (including preprints).
See what I've reposted in just the last couple of hours...

Reposted by Simon Michaeli

Fantin Mesny @mesny.bsky.social · Aug 15

📣 NEW PREPRINT 📝

We identified evolutionary origins of many fungal effectors!
We show that fungi secrete lots of antimicrobial proteins, and that some of them were repurposed by plant pathogens for host immune suppression.
www.biorxiv.org/content/10.1...

cc @teamthomma.bsky.social

Plant-associated fungi co-opt ancient antimicrobials for host manipulation

Evolutionary histories of effector proteins secreted by fungal pathogens to mediate plant colonization remain largely elusive. While most functionally characterized effectors modulate plant immunity, ...

www.biorxiv.org

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Reposted by Simon Michaeli

Maddy Seale @maddyseale.bsky.social · Aug 15

Out in @science.org The crazy sequence of events from planting maize in dense fields. Density-dependent linalool release triggers release of compounds into the soil affecting microbes and plants.
Article: www.science.org/doi/10.1126/...
Perspective: www.science.org/doi/10.1126/...
#PlantScience

Linalool-triggered plant-soil feedback drives defense adaptation in dense maize plantings

High planting density boosts crop yields but also heightens pest and pathogen risks. How plants adapt their defenses under these conditions remains unclear. In this study, we reveal that maize enhance...

www.science.org

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Reposted by Simon Michaeli

Neta Shlezinger @shlezingerlab.bsky.social · Aug 14

🚨 Fungi + viruses + mammalian lungs? Buckle up! Our new paper in
@natmicrobiol.nature.com
uncovers the story of a deadly fungus and its gnarly viral hitchhiker — and how this duo may change how we diagnose & treat fungal disease 🍄🫁🚨 doi.org/10.1038/s415... ⬇️

Aspergillus fumigatus dsRNA virus promotes fungal fitness and pathogenicity in the mammalian host - Nature Microbiology

A mycovirus infecting the pathogenic fungus Aspergillus fumigatus enhances its stress tolerance and virulence in mice.

doi.org

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Reposted by Simon Michaeli

Sjon Hartman @hartman-plantlab.com · Aug 16

It's critical to switch off ethylene signalling once it has done its job during developmental transitions and stress acclimation. Excited to see this work led by @eleazarrodriguez.bsky.social now on BioRxiv. Happy @rimchaudhury15.bsky.social and I could contribute a bit to the story! #plantscience

bioRxiv Plant Bio @biorxiv-plants.bsky.social · Aug 16

Autophagic degradation of EIN3 ensures developmental plasticity and recovery from environmental stress in Arabidopsis https://www.biorxiv.org/content/10.1101/2025.08.13.669664v1

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Reposted by Simon Michaeli

Yasin Dagdas @plantophagy.bsky.social · Aug 11

If you’re enjoying some calm while others are on holiday, here’s a #NEW #preprint to dive into — led by the brilliant @vbcscitraining.bsky.social student A. Abdrakhmanov:
👇 A quick thread + link:
www.biorxiv.org/content/10.1...

Ancestral P-body proteins rewired for autophagic recycling in the early land plant Marchantia polymorpha

Processing bodies (P-bodies) are conserved ribonucleoprotein (RNP) granules central to RNA metabolism across eukaryotes. Although the mechanisms underlying their assembly are well understood, the path...

www.biorxiv.org

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Reposted by Simon Michaeli

Elias Adriaenssens @elias-adriaenssens.bsky.social · Aug 13

Absolutely honoured to see our work featured on this month’s cover! 🎉🧬

Artwork by the incredibly talented @doroteaartscience.bsky.social 👇

Nature Cell Biology @natcellbio.nature.com · Aug 12

🏖️Our August issue's out!
Cover: Flexibility of #autophagy initiation

👉🏼Review on #metabolism in #embryogenesis #devbio
👉🏼Review on #DNArepair
🔬 #ribosomes #neurodevelopment #mitophagy #ferroptosis #stemcells #epigenetics #leukemia #antitumor immunity & more!
www.nature.com/ncb/volumes/...

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Reposted by Simon Michaeli

Yasin Dagdas @plantophagy.bsky.social · Aug 8

Some experiments advance science. Others advance the reviewer’s sense of power. Guess which costs more. #FridayThoughts

The Sopranos Tony Soprano GIF

ALT: The Sopranos Tony Soprano GIF

media.tenor.com

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Reposted by Simon Michaeli

Oded Rechavi @odedrechavi.bsky.social · Jul 31

🥂This was the highlight of my year. The "instigators", led by local master of the ceremony @svobodalab.bsky.social will never forget the privilege of organizing it and i think every participant will treasure the experience forever ❤️ @nature.com @josiegz.bsky.social www.nature.com/articles/d41...

Scientific bedlam at the world’s weirdest and wildest research conference

Woodstock Bio2 + Night Science aimed to encourage collaborations through creativity. The walk-on music for presentations was fun, too.

www.nature.com

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Simon Michaeli @michaelilab.bsky.social · Aug 2

My country is hijacked by extremists. Polls indicate the overwhelming majority wishes the war to end and release of all hostages. Yet no one up there gives a damn!

Reposted by Simon Michaeli

Volcani Institute @volcaniinstitute.bsky.social · Jul 27

Read this manuscript, which describes the in-vivo production of double-stranded RNA (dsRNA) against ToBRFV, a devastating #virus threatening #tomato #crops worldwide. 🍅 👉 academic.oup.com/jxb/advance-...

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Reposted by Simon Michaeli

Marcel Dickmanns | 🌿❄️🔬 @madic.bsky.social · Jul 26

New preprint: In situ Architecture of #Plasmodesmata.

Using #cryoET, #AlphaFold & proteomics, we uncover the native organization of plant intercellular nanopores.

🔗 doi.org/10.1101/2025...

🧪🧵1/n
#teamtomo #PlantScience #Physcomitrium #Arabidopsis #cryoEM

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Reposted by Simon Michaeli

Jesús Martínez-Gómez @jesusgm.bsky.social · Jul 25

A little belated but I've started a faculty position at Ecology, Evolution and Marine Biology department at @ucsantabarbara.bsky.social. I'm absolutely stoked! I'll be recruiting at all levels and will be at #Botany2025

Reach out!

www.martinezgomezlab.com

Martinez-Gomez Lab

Plant Evo-Devo

www.martinezgomezlab.com

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Simon Michaeli @michaelilab.bsky.social · Jul 25

It's proteolysis!
#PlantScience

UCDavisPlants @ucdavisplants.bsky.social · Jul 23

🍊 From Science: Stabilizing MYC2 in citrus trees boosts resistance to Huanglongbing (Citrus greening disease). AI-designed peptides offer a new path for controlling uncultivable pathogens. (Daniel J. Kliebenstein)

▶️ www.science.org/doi/full/10....
#PlantPathology #PlantScience

Fig. 1. Regulation of HLB resistance by a U-box E3 ubiquitin ligase PUB21 and its dominant-negative paralog PUB21DN.
(A) Neighbor-joining phylogenetic tree of Rutaceae species and other species. The numbers of asterisks indicate the HLB resistance level of each species, and orange bars indicate the presence of a helitron transposon in PUB21 promoters. Green and brown bars indicate whether PUB21 or PUB21DN was present. (B) Transcriptomic analysis of plant U-box genes (PUBs) family in Citrus species in response to CLas infection. FC, fold change.

Reposted by Simon Michaeli

Czech Academy of Sciences @czechacademy.bsky.social · Jul 25

The first high-resolution, predictive biodiversity map of Earth’s underground mycorrhizal fungal communities shows over 90% of underground mycorrhizal fungal ecosystems are unprotected, threatening carbon drawdown and ecosystem resilience to climate extremes.

www.nature.com/articles/s41...

Global hotspots of mycorrhizal fungal richness are poorly protected - Nature

Machine-learning algorithms trained on 25,000 geolocated soil samples are used to create high-resolution global maps of mycorrhizal fungi, revealing that less than 10% of their biodiversity hotspots a...

www.nature.com

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Reposted by Simon Michaeli

mariebarberon.bsky.social @mariebarberon.bsky.social · Jul 22

Very excited that our work on directional symplastic transport in differentiated root is now published!A developmental switch controls cell-to-cell transport in roots via pectin-linked plasmodesmata changes: Molecular Plant www.cell.com/molecular-pl...

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Simon Michaeli @michaelilab.bsky.social · Jul 18

I don't remember myself so pessimistic and fearing the future as I was in recent weeks. We are led by a cynical and radical group of people.They must be replaced, soon!

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Simon Michaeli @michaelilab.bsky.social · Jun 28

Yes, everything as usual now...

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Simon Michaeli @michaelilab.bsky.social · Jun 27

I would like to thank all the nice Czech people I met during the week+ of being a refugee, and especially Viktor, Martin Potocky, and Roman Pleskot of the Institute of Experimental Botany. Thank you guys! 🙏 And what a great place to get stranded at!

Simon Michaeli @michaelilab.bsky.social · Jun 27

So I got stranded in Prague after the incredible #TCTeAC Woodstock Bio due to the F war. But as the old saying goes, if you have lemons make a Mojito🍹. So I contacted Viktor Zarsky, who immediately organized a seminar @charlesuni.cuni.cz which yilded a collaboration!

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