Michal Minczuk
@mitogene.bsky.social
190 followers
140 following
13 posts
Prof. at University of Cambridge @mrc-mbu.bsky.social; co-founder of Pretzeltx.com
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Reposted by Michal Minczuk
Reposted by Michal Minczuk
Reposted by Michal Minczuk
Reposted by Michal Minczuk
www.MitoWorld.org
@mitoworld.bsky.social
· Jun 23
Mechanisms of Mitochondrial DNA Mutation and Repair - MitoWorld
If our website is MitoWorld, the Mechanisms of Mitochondrial DNA Mutation and Repair conference was the introductory gathering of what could be called “mtDNA World.” The organizers, Patrick Chinnery (...
mitoworld.org
Reposted by Michal Minczuk
Reposted by Michal Minczuk
Taylor Lab
@taylorlabncl.bsky.social
· May 24
The Guardian
@theguardian.com
· May 23
Blood test developed that could speed up diagnosis of rare diseases in babies
Scientists say new approach means effects of many genetic mutations can be analysed at once and yield results in days
A new blood-based test that could help speed up diagnoses for children born with rare genetic disorders has been developed by researchers in an effort to provide answers – and treatments – sooner.
Rare genetic disorders include a host of conditions, from cystic fibrosis to diseases relating to the mitochondria – the powerhouses of our cells. However, getting a diagnosis can be arduous. Continue reading...
www.theguardian.com
Reposted by Michal Minczuk
Reposted by Michal Minczuk
Reposted by Michal Minczuk
Michal Minczuk
@mitogene.bsky.social
· Apr 15
Reposted by Michal Minczuk
Reposted by Michal Minczuk
Michal Minczuk
@mitogene.bsky.social
· Apr 10
Michal Minczuk
@mitogene.bsky.social
· Apr 9
Michal Minczuk
@mitogene.bsky.social
· Apr 9
Clinically translatable mitochondrial gene therapy in muscle using tandem mtZFN architecture | EMBO Molecular Medicine
imageimageEfficient mitochondrial gene therapy is achieved with a novel tandem zinc finger nuclease (mtZFN) architecture delivered via adeno-associated viral (AAV) vectors, significantly reducing mutation loads in muscle tissue and rescuing ...
www.embopress.org
Michal Minczuk
@mitogene.bsky.social
· Apr 4
Michal Minczuk
@mitogene.bsky.social
· Apr 4
Michal Minczuk
@mitogene.bsky.social
· Apr 4
Pretzel Therapeutics Initiates Phase 1 Clinical Study Evaluating PX578, Lead Therapeutic in its Bioenergetics Restoration Franchise » Pretzel Therapeutics
First-in-class approach to targeting mitochondrial DNA polymerase (POLG) with disease modifying potential across mitochondrial DNA depletion syndromes
www.pretzeltx.com