Reposted
The FDA rejects tolebrutinib, an oral Bruton’s tyrosine kinase inhibitor, for non-relapsing secondary progressive multiple sclerosis www.thepharmaletter.com/pharmaceutic...
US FDA rejects Sanofi filing for tolebrutinib in progressive MS
French pharma major Sanofi (Euronext: SAN) has received a Complete Response Letter (CRL) from the US regulator for tolebrutinib in non-relapsing secondary progressive multiple sclerosis, extending a d...
www.thepharmaletter.com
December 26, 2025 at 10:34 PM
The FDA rejects tolebrutinib, an oral Bruton’s tyrosine kinase inhibitor, for non-relapsing secondary progressive multiple sclerosis www.thepharmaletter.com/pharmaceutic...
Reposted
Let's keep everyone company this year. I'll be around on christmas day with #joinin whether you need fun or a bit of support or a rant.
No-one should feel alone on christmas day.
No-one should feel alone on christmas day.
December 23, 2025 at 6:45 PM
Let's keep everyone company this year. I'll be around on christmas day with #joinin whether you need fun or a bit of support or a rant.
No-one should feel alone on christmas day.
No-one should feel alone on christmas day.
Reposted
Tomorrow evening it’ll be my annual duty to vaguely shepherd the activity on the #duvetknowitschristmas hashtag and urge people to give small sums to charity. 7.30pm? Something like that?
December 23, 2025 at 7:26 PM
Tomorrow evening it’ll be my annual duty to vaguely shepherd the activity on the #duvetknowitschristmas hashtag and urge people to give small sums to charity. 7.30pm? Something like that?
Reposted
Message to President Trump from Greenland Tupaarnaq made by a greenlandic woman, which is a EU citizen.
December 23, 2025 at 4:09 PM
Message to President Trump from Greenland Tupaarnaq made by a greenlandic woman, which is a EU citizen.
Reposted
This was my biggest tweet over in the bad place. It will live here now. 🧙♀️🎄
December 11, 2024 at 2:40 AM
This was my biggest tweet over in the bad place. It will live here now. 🧙♀️🎄
Reposted
Pantone just updated their Color Of The Year
December 20, 2025 at 7:23 PM
Pantone just updated their Color Of The Year
Reposted
Danielle Smith did not run on these proposals; indeed, she ran against many of them. If she believes Albertans are with her, she should call an election now.”
Alberta NDP leader Naheed Nenshi tears into the release and findings of the Alberta Next Panel.
Alberta NDP leader Naheed Nenshi tears into the release and findings of the Alberta Next Panel.
December 19, 2025 at 10:21 PM
Danielle Smith did not run on these proposals; indeed, she ran against many of them. If she believes Albertans are with her, she should call an election now.”
Alberta NDP leader Naheed Nenshi tears into the release and findings of the Alberta Next Panel.
Alberta NDP leader Naheed Nenshi tears into the release and findings of the Alberta Next Panel.
Reposted
The Vanity Fair photographer knew what he was doing. (I doubt I’m the first to notice this but it hasn’t graced my TL)
December 18, 2025 at 1:11 AM
The Vanity Fair photographer knew what he was doing. (I doubt I’m the first to notice this but it hasn’t graced my TL)
Reposted
"My Grandfather's Cat" is a cross-Canada organization that helps dying seniors find homes for their beloved animals. They also offer a senior's pet food pantry, to help support low income seniors.
Please consider donating as a gift for the pet lover in your life.
www.mygrandfatherscat.ca
Please consider donating as a gift for the pet lover in your life.
www.mygrandfatherscat.ca
support fill the dishes — My Grandfather's Cat
www.mygrandfatherscat.ca
December 13, 2025 at 4:57 PM
"My Grandfather's Cat" is a cross-Canada organization that helps dying seniors find homes for their beloved animals. They also offer a senior's pet food pantry, to help support low income seniors.
Please consider donating as a gift for the pet lover in your life.
www.mygrandfatherscat.ca
Please consider donating as a gift for the pet lover in your life.
www.mygrandfatherscat.ca
Reposted
Our system is built so that courts are absolutely gatekeepers with the express purpose of keeping shit heels like her from abandoning the rule of law altogether.
#AbLeg
#AbLeg
Smith: why am I not an American Governor unfettered by Canadian law?
Alberta’s Smith says courts should not be gatekeepers on constitutional questions
Alberta Premier Danielle Smith says those seeking an independence referendum should not have “gatekeepers,” like the courts, standing in their way.
www.ctvnews.ca
December 7, 2025 at 4:59 PM
Our system is built so that courts are absolutely gatekeepers with the express purpose of keeping shit heels like her from abandoning the rule of law altogether.
#AbLeg
#AbLeg
Reposted
We are pleased to accept the FIFA Punctuality Prize.
December 6, 2025 at 10:17 PM
We are pleased to accept the FIFA Punctuality Prize.
Reposted
The new data show Alberta, not Ontario as previously understood, has the highest case count of any province, despite having a much smaller population. Ontario publicly reports probable cases.
www.theglobeandmail.com/canada/alber...
www.theglobeandmail.com/canada/alber...
Alberta government rejected expert advice to report probable measles cases, documents show
New data show at least 450 probable cases were identified in the province, bringing the total to nearly 2,500 since the outbreak began last spring
www.theglobeandmail.com
December 6, 2025 at 11:36 PM
The new data show Alberta, not Ontario as previously understood, has the highest case count of any province, despite having a much smaller population. Ontario publicly reports probable cases.
www.theglobeandmail.com/canada/alber...
www.theglobeandmail.com/canada/alber...
Reposted
Reposted
Premier Danielle Smith wants to cut off debate on Bill 11, her disastrous two-tier healthcare plan, so the government can dodge questions and leave for an early holiday break.
Show them we’re watching.
Send a message: notwotier.ca/sendmessage
Show them we’re watching.
Send a message: notwotier.ca/sendmessage
URGENT: Stop Two-Tier Healthcare. Send a Direct Message Now.
We have to defend and promote Universal Public Healthcare before it's too late.
notwotier.ca
December 6, 2025 at 2:12 PM
Premier Danielle Smith wants to cut off debate on Bill 11, her disastrous two-tier healthcare plan, so the government can dodge questions and leave for an early holiday break.
Show them we’re watching.
Send a message: notwotier.ca/sendmessage
Show them we’re watching.
Send a message: notwotier.ca/sendmessage
Reposted
Person who actually deserves a trophy is the artist who made the FIFA peace prize trophy look like everyone in the entire world holding their head in their hands out of secondhand embarrassment
December 5, 2025 at 7:38 PM
Person who actually deserves a trophy is the artist who made the FIFA peace prize trophy look like everyone in the entire world holding their head in their hands out of secondhand embarrassment
Reposted
Disabled isn't a dirty word, and it's fine to work through internalized ableism if you were raised thinking so. We live in an ableist world.
December 4, 2025 at 12:06 AM
Disabled isn't a dirty word, and it's fine to work through internalized ableism if you were raised thinking so. We live in an ableist world.
Reposted
Raxhel Wright, artist who works with textiles, free machine embroidery over cut and pieced fabrics #WomensArt
December 3, 2025 at 6:19 AM
Raxhel Wright, artist who works with textiles, free machine embroidery over cut and pieced fabrics #WomensArt
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Posting stupid memes after being accused of murder is the response of a sneering, spoiled punk who has been caught doing wrong and is now daring the local fuzz to take him in and risk the anger of his rich dad—a role fulfilled by Donald Trump, in this case.
www.theatlantic.com/ideas/2025/1...
www.theatlantic.com/ideas/2025/1...
Pete Hegseth Needs to Go—Now
A man with such contempt for the military should not run the Pentagon.
www.theatlantic.com
December 2, 2025 at 12:02 AM
Posting stupid memes after being accused of murder is the response of a sneering, spoiled punk who has been caught doing wrong and is now daring the local fuzz to take him in and risk the anger of his rich dad—a role fulfilled by Donald Trump, in this case.
www.theatlantic.com/ideas/2025/1...
www.theatlantic.com/ideas/2025/1...
Reposted
Reposted
Kelly: He runs around on stage talking about lethality and the warrior ethos.. That’s not the message that should be coming from the Secretary of Defense… He runs around on a stage like he’s a 12 year old playing army. It’s embarrassing.
December 1, 2025 at 9:12 PM
Kelly: He runs around on stage talking about lethality and the warrior ethos.. That’s not the message that should be coming from the Secretary of Defense… He runs around on a stage like he’s a 12 year old playing army. It’s embarrassing.
Reposted
David Byrne: Tiny Desk Concert
YouTube video by NPR Music
www.youtube.com
December 2, 2025 at 12:35 AM
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So the guy selling COVID supplies to the government was hoping for more intense COVID waves, a direct outcome of policy decisions by a government he influenced through dozens of channels.
November 30, 2025 at 6:48 PM
So the guy selling COVID supplies to the government was hoping for more intense COVID waves, a direct outcome of policy decisions by a government he influenced through dozens of channels.
Reposted
People couldn't afford the fees involved in appealing the decision anyway so the point is moot. Moot & cruel.
"Bill 12 also bars appeals of the decision to move existing AISH clients onto ADAP and gives the minister power to decide which other benefit decisions can be appealed."
"Bill 12 also bars appeals of the decision to move existing AISH clients onto ADAP and gives the minister power to decide which other benefit decisions can be appealed."
‘We didn’t ask for change’: Alberta gov’t draws ire with tabling of AISH overhaul
Key changes to Alberta’s disability support system are drawing sharp criticism from recipients, economists and anti-poverty advocates after the provincial government embedded an overhaul of the AISH p...
www.ctvnews.ca
November 29, 2025 at 6:48 PM
People couldn't afford the fees involved in appealing the decision anyway so the point is moot. Moot & cruel.
"Bill 12 also bars appeals of the decision to move existing AISH clients onto ADAP and gives the minister power to decide which other benefit decisions can be appealed."
"Bill 12 also bars appeals of the decision to move existing AISH clients onto ADAP and gives the minister power to decide which other benefit decisions can be appealed."
Reposted
Photographer Kathrin Swoboda captured amazing images of a red wing blackbird's song, visible via the bird's breath in cold air and early light #WomensArt
November 29, 2025 at 5:34 AM
Photographer Kathrin Swoboda captured amazing images of a red wing blackbird's song, visible via the bird's breath in cold air and early light #WomensArt