Matthew Williams
@mp-williams.bsky.social
200 followers 97 following 6 posts
Archaeogeneticist by day and night. Postdoc in the Huber Lab at Penn State. Lover of the ancient Near East, philosophy, and coffee.
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Reposted by Matthew Williams
anthropogeny.org
Don't miss Ancient DNA: New Revelations, a free, public CARTA symposium! 🧬💡

Friday, November 7, 2025 1:00–5:30 PM (Pacific)

In-person at the Salk Institute & Live Webcast

For more details and registration, visit: carta.anthropogeny.org

#carta #cartaucsd #ancientdna
mp-williams.bsky.social
Thanks @boothicus.bsky.social! this was, for me, one of the most intriguing outcomes... was excellent work by PhD candidate Troy LaPolice.
Reposted by Matthew Williams
haam-community.bsky.social
🏛️ Still unsure how to spend your afternoon in Turin 🇮🇹 before @isba11.bsky.social starts, come to our #HAAMmeeting @Complesso Aldo Moro and meet young & inspiring researchers!
💻 If you're not in Turin, you can join us online, too.
📖 DM us! #aDNA #HAAMcommunity @isbarchaeology.bsky.social
Reposted by Matthew Williams
dgron.bsky.social
It's out! 😀

THE MAP: EXPANSION OF FARMING IN WESTERN EURASIA, 9600-4000 BCE
2025.1

Regional updates, particularly 🇺🇦. Colour and greyscale resolutions, and much asked for colour code and legend.

@barbarahorejs.bsky.social @leizarchaeology.bsky.social @oeai.bsky.social

zenodo.org/records/1688...
Reposted by Matthew Williams
labogden.bsky.social
NIH is accepting comments about limiting research publication costs. 1. Disallow pub costs, 2. $2K limit, 3. $3K if reviewers are compensated, 4. 0.8% of award (so $250K grant can pay $2K/year on pubs), 5. $6K limit on pub + limit on % of grant spent on pub costs. 🧪

grants.nih.gov/grants/guide...
NOT-OD-25-138: Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs NOT-OD-25-138. NIH
grants.nih.gov
Reposted by Matthew Williams
Reposted by Matthew Williams
jbakcoleman.bsky.social
But perhaps most critically, it’s (imo) irresponsible to attribute this to *science* as a whole; suggesting it’s a monolith when things like the image duplication retractions are pretty limited to a unique corner of science under sleuth spotlights.
Reposted by Matthew Williams
ryangutenkunst.bsky.social
If you're new to demographic history inference from population genomics, try this webapp I created to illustrate how dadi fits bottleneck models to site frequency spectra: ryangutenkunst-dadi-two-epoch.hf.space . It even outputs files for submitting to the GHIST competition! ghi.st
Logo for the Genomic History Inference Strategies Tournament.
Reposted by Matthew Williams
mootspoints.bsky.social
🧬🏺Calling everyone interested in the intersection of archaeological theory and ancient DNA!

Thrilled to be co-organizing a session for #TRAC2025 with @ezgimou.bsky.social

The virtual conference will be held October 22 - 24 and the call for abstracts is now open. Come join us!
ezgimou.bsky.social
🧪 🏺
Excited to co-organize a session with @mootspoints.bsky.social at #TRAC2025!
🧬 Integrating Ancient DNA with Archaeological Theory and Practice
We welcome papers on mobility, migration, & identity in the Roman world and beyond.
📢 Call for abstracts now open! Please spread the word.
#aDNA #science
Reposted by Matthew Williams
ezgimou.bsky.social
🧪 🏺
Excited to co-organize a session with @mootspoints.bsky.social at #TRAC2025!
🧬 Integrating Ancient DNA with Archaeological Theory and Practice
We welcome papers on mobility, migration, & identity in the Roman world and beyond.
📢 Call for abstracts now open! Please spread the word.
#aDNA #science
Reposted by Matthew Williams
skylerberardi.bsky.social
Check out our paper in Evolution Letters!

We used D. melanogaster pigmentation as a focal trait to explore parallelism in phenotypic and genomic responses to environmental change - read more at the link below 👇
evolletters.bsky.social
How predictably does complex trait adaptation proceed over space and time in wild populations?
doi.org/10.1093/evle...

Now in @evolletters.bsky.social by @skylerberardi.bsky.social, @paulrschmidt.bsky.social et al.

📷: Dr. Rush Dhillon
Figure showing the experimental overview as a graphic. Remaining alt text taken from the figure caption in the paper: (A) we sampled flies from six wild orchard populations ranging from Homestead, FL, to Lancaster, MA, and established isofemale lines in the laboratory. (B) We returned to a focal orchard in Media, PA, at early- and late-season timepoints and collected flies to capture evolutionary patterns following winter and summer conditions. (C) We then seeded outdoor mesocosms (N = 9) with an outbred population originating from early-season collections in Media, PA, and sampled flies at the end of summer (mid-season) and fall (late-season) to determine if seasonal patterns are recapitulated in experimental populations controlled for migration, drift, and cryptic population structure. (D) Across each wild or experimental context, we sampled flies, established lines in the lab, completed common garden treatment to remove environmental effects, and scored females for abdominal pigmentation. We also conducted pooled DNA sequencing on additional flies sampled from each population to map genomic patterns for candidate pigmentation SNPs.
Reposted by Matthew Williams
evolletters.bsky.social
How predictably does complex trait adaptation proceed over space and time in wild populations?
doi.org/10.1093/evle...

Now in @evolletters.bsky.social by @skylerberardi.bsky.social, @paulrschmidt.bsky.social et al.

📷: Dr. Rush Dhillon
Figure showing the experimental overview as a graphic. Remaining alt text taken from the figure caption in the paper: (A) we sampled flies from six wild orchard populations ranging from Homestead, FL, to Lancaster, MA, and established isofemale lines in the laboratory. (B) We returned to a focal orchard in Media, PA, at early- and late-season timepoints and collected flies to capture evolutionary patterns following winter and summer conditions. (C) We then seeded outdoor mesocosms (N = 9) with an outbred population originating from early-season collections in Media, PA, and sampled flies at the end of summer (mid-season) and fall (late-season) to determine if seasonal patterns are recapitulated in experimental populations controlled for migration, drift, and cryptic population structure. (D) Across each wild or experimental context, we sampled flies, established lines in the lab, completed common garden treatment to remove environmental effects, and scored females for abdominal pigmentation. We also conducted pooled DNA sequencing on additional flies sampled from each population to map genomic patterns for candidate pigmentation SNPs.
Reposted by Matthew Williams
marcocapo.bsky.social
Turns out imputation of introgressed archaic regions in aDNA works really well — sometimes even better than for the rest of the genome. More on this (and other cool results) in our new preprint 👇 #aDNA #ArchaicIntrogression #imputation
doi.org/10.1101/2025...
Archaic ancestry inference in imputed ancient human genomes
When modern humans expanded from Africa into Eurasia, they interbred with archaic hominins such as Neanderthals and Denisovans. This groundbreaking discovery, made in part possible through the genomic...
doi.org
Reposted by Matthew Williams
yun-s-song.bsky.social
The 2026 Probabilistic Modeling in Genomics (ProbGen) meeting will be held at UC Berkeley, March 25-28, 2026. We have an amazing list of keynote speakers and session chairs:
probgen2026.github.io

Please help spread the news.
Home - ProbGen 2026
Your Site Description
probgen2026.github.io
Reposted by Matthew Williams
mootspoints.bsky.social
Come check out my poster this afternoon! On the language we use to talk mobility in ancient DNA studies #SMBE2025
Reposted by Matthew Williams
epigenci.bsky.social
Hence, this highlights the fundamental difference btw genomic and family h2. The former is considering millions of years of mutation while the latter is looking at everything but mutations over a very short period of time.
Reposted by Matthew Williams
epigenci.bsky.social
I can now finally speak out loud my honest thoughts on missing heritability or the genomics/family gap in h2 estimates.
Based on new paper the *issue* is a feature and not a bug.

TLDR: SNP h2 only captures mutational variance and family h2 captures everything but mutation.
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