Alexey Nesvizhskii
@nesvilab.bsky.social
Godfrey D. Stobbe Professor of Bioinformatics at U of Michigan. Trained as a theoretical physicist, now focusing on proteomics and proteogenomics. https://fragpipe.nesvilab.org/
Reposted by Alexey Nesvizhskii
The May Institute, if you don't know, combines the full workup of generating mass spec proteomics data all the way to doing the statistics.
This year has a few new modules, like FragPipe with @nesvilab.bsky.social and @fcyucn.bsky.social, so even if you've attended in the past, check it out!
This year has a few new modules, like FragPipe with @nesvilab.bsky.social and @fcyucn.bsky.social, so even if you've attended in the past, check it out!
January 20, 2026 at 11:34 PM
The May Institute, if you don't know, combines the full workup of generating mass spec proteomics data all the way to doing the statistics.
This year has a few new modules, like FragPipe with @nesvilab.bsky.social and @fcyucn.bsky.social, so even if you've attended in the past, check it out!
This year has a few new modules, like FragPipe with @nesvilab.bsky.social and @fcyucn.bsky.social, so even if you've attended in the past, check it out!
Reposted by Alexey Nesvizhskii
This work led by Elena Levi-D'Ancona, a recent PhD graduate in our lab, was our first cover and only possible due to our amazing team and outstanding collaborators, including @nesvilab.bsky.social and Orian Shirihai, and funding from NIDDK, Breakthrough T1D, and the VA! Thank you! 🤗🙌 2/fin
October 8, 2025 at 8:28 PM
This work led by Elena Levi-D'Ancona, a recent PhD graduate in our lab, was our first cover and only possible due to our amazing team and outstanding collaborators, including @nesvilab.bsky.social and Orian Shirihai, and funding from NIDDK, Breakthrough T1D, and the VA! Thank you! 🤗🙌 2/fin
exact quote is "this site is being blocked due to DOJ Bulk Sensitive Data Regulations as the site is hosted in a Geo-Fenced country". I think replication of the data would be the only option for us in the foreseeable future.
September 10, 2025 at 6:01 PM
exact quote is "this site is being blocked due to DOJ Bulk Sensitive Data Regulations as the site is hosted in a Geo-Fenced country". I think replication of the data would be the only option for us in the foreseeable future.
I am not going to answer for “the field” but - in our tools - the short answer is yes. From introducing localization-aware open search, to Crystal-C artifact removal pubs.acs.org/doi/10.1021/..., to PTM-Shepherd summarization and visualization tools, we provide guardrails if not guidelines.
Crystal-C: A Computational Tool for Refinement of Open Search Results
Shotgun proteomics using liquid chromatography coupled to mass spectrometry (LC-MS) is commonly used to identify peptides containing post-translational modifications. With the emergence of fast databa...
pubs.acs.org
August 20, 2025 at 11:44 PM
I am not going to answer for “the field” but - in our tools - the short answer is yes. From introducing localization-aware open search, to Crystal-C artifact removal pubs.acs.org/doi/10.1021/..., to PTM-Shepherd summarization and visualization tools, we provide guardrails if not guidelines.
Have you compared FragPipe on i9 vs comparably priced AMD threadripper? I put a request to our IT to get me one but they do not support core imaging of AMD machines. I am still recommending a good Xeon or i9 to folks who want a standard desktop to run FragPipe on a < $5k machine but want to test AMD
July 24, 2025 at 7:09 PM
Have you compared FragPipe on i9 vs comparably priced AMD threadripper? I put a request to our IT to get me one but they do not support core imaging of AMD machines. I am still recommending a good Xeon or i9 to folks who want a standard desktop to run FragPipe on a < $5k machine but want to test AMD
I miss Twitter a bit. With its outrageous commercials and all those gorgeously looking “Lucy564” people who seemed to wanted to follow me in droves. Ok, not really. I do occasionally check Bluesky but I only see posts from a few (mostly same) people. Lack of critical mass?
June 14, 2025 at 5:03 PM
I miss Twitter a bit. With its outrageous commercials and all those gorgeously looking “Lucy564” people who seemed to wanted to follow me in droves. Ok, not really. I do occasionally check Bluesky but I only see posts from a few (mostly same) people. Lack of critical mass?