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Javeria Hashmi

@netphys.bsky.social

1.4K followers 2.6K following 110 posts

Neuroscientist: pain perception, human neuroimaging, networks and graphs, cautious Neuro AI, clinical translation

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Javeria Hashmi @netphys.bsky.social · Mar 4

***New paper from our lab*** By Jennika Veinot

Low working memory underpins the association between aberrant functional properties of pain modulation circuitry and chronic back pain severity.

Journal of PAIN, 2025

www.sciencedirect.com/science/arti...

#pain #neuroscience #cognition

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Javeria Hashmi @netphys.bsky.social · Jun 24

@Ohbm Talairach lecture. All about AI and how consortiums are fueling biomarker development.

#OHBM2025 @ohbmtrainees.bsky.social

Javeria Hashmi @netphys.bsky.social · Jun 14

Mary Oliver

Javeria Hashmi @netphys.bsky.social · Jun 14

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Javeria Hashmi @netphys.bsky.social · Jun 14

Amazing story. Awesome guy Mr.Rogers

Reposted by Javeria Hashmi

Bertoglio lab (FMC/UFSC) @bertogliolab.bsky.social · Jun 5

Stimulus-specific and adaptive value representations in the basolateral amygdala in male mice
www.nature.com/articles/s41...

Stimulus-specific and adaptive value representations in the basolateral amygdala in male mice - Nature Communications

How basolateral amygdala represents the specific value of rewards remains unclear. Here the authors find that basolateral amygdala neurons assign stimulus-specific values to different rewards and rapi...

www.nature.com

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Reposted by Javeria Hashmi

Efrén Pérez @efrenpolipsy.bsky.social · Jun 3

As the quarter ends at UCLA 🇲🇽🇺🇸

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Reposted by Javeria Hashmi

Michael Pereira @meaperei.bsky.social · Jun 1

New “version of record” in @elife.bsky.social! ‬

We recorded neurons in the thalamus and subthalamic nucleus of humans and found both sensory- and perception-selective neurons with two distinct latencies!

7-year project with @nfaivre.bsky.social + @foscobernasconi.bsky.social.

A short thread 👇

Subcortical correlates of consciousness with human single neuron recordings

Subcortical brain structures contain neurons encoding subjective reports of stimulus detection in human participants, suggesting a role for conscious perception.

elifesciences.org

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Reposted by Javeria Hashmi

Decision, Action, and Neural Computation (DANC) lab @danclab.bsky.social · Jun 2

It's been a while since our last laminar MEG paper, but we're back! This time we push beyond deep versus superficial distinctions and go whole hog. Check it out- lots more exciting stuff to come! 🧠📈

Maciek Szul @maciekszul.bsky.social · Jun 2

🚨🚨🚨PREPRINT ALERT🚨🚨🚨
Neural dynamics across cortical layers are key to brain computations - but non-invasively, we’ve been limited to rough "deep vs. superficial" distinctions. What if we told you that it is possible to achieve full (TRUE!) laminar (I, II, III, IV, V, VI) precision with MEG!

Overview of the simulation strategy and analysis. a) Pial and white matter boundaries
surfaces are extracted from anatomical MRI volumes. b) Intermediate equidistant surfaces are
generated between the pial and white matter surfaces (labeled as superficial (S) and deep (D)
respectively). c) Surfaces are downsampled together, maintaining vertex correspondence across
layers. Dipole orientations are constrained using vectors linking corresponding vertices (link vectors).
d) The thickness of cortical laminae varies across the cortical depth (70–72), which is evenly sampled
by the equidistant source surface layers. e) Each colored line represents the model evidence (relative
to the worst model, ΔF) over source layer models, for a signal simulated at a particular layer (the
simulated layer is indicated by the line color). The source layer model with the maximal ΔF is
indicated by “˄”. f) Result matrix summarizing ΔF across simulated source locations, with peak
relative model evidence marked with “˄”. g) Error is calculated from the result matrix as the absolute
distance in mm or layers from the simulated source (*) to the peak ΔF (˄). h) Bias is calculated as the
relative position of a peak ΔF(˄) to a simulated source (*) in layers or mm.

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Reposted by Javeria Hashmi

Vincent Breton-Provencher @vincentbp.bsky.social · Jun 2

My laboratory at Université Laval in Québec City, Canada, is looking for a postdoc to study how neuromodulatory systems impact cortical processing during foraging behavior. This fully-funded position offers a collaborative environment in a great city. More info👇

can-acn.org/postdoctoral...

Postdoctoral position available in the Breton-Provencher Lab at Université Laval to study neuromodulatory systems and foraging behavior – Canadian Association for Neuroscience

can-acn.org

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Reposted by Javeria Hashmi

Sainsbury Wellcome Centre @sainsburywellcome.bsky.social · May 14

Read the full paper ‘Dopaminergic action prediction errors serve as a value-free teaching signal’ in @natureportfolio.nature.com

@gatsbyucl.bsky.social @imperialcollegeldn.bsky.social

www.nature.com/articles/s41...

Dopaminergic action prediction errors serve as a value-free teaching signal - Nature

Dopaminergic action prediction error signals are used by mice as a value-free teaching signal to reinforce stable sound–action associations in the tail of the striatum.

www.nature.com

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Javeria Hashmi @netphys.bsky.social · May 23

Lab photo @canacn.bsky.social

Come see posters from these awesome people presenting their latest research!

#CANACN2025
#PsychSciSky
#neuroscience
#PhD

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Javeria Hashmi @netphys.bsky.social · May 22

We are having an amazing time learning about the brain circuitry at the Canadian Association for Neuroscience meeting in Toronto. Not a lot of human brain neuroimaging or pain mechanisms, but hey, that can change!

#CANACN2025
#neuroscience

@canacn.bsky.social

Javeria Hashmi @netphys.bsky.social · May 20

Sheena Josselyn speaking about history of memory research in Toronto. A CAN ACN symposium. #canacn2025

Javeria Hashmi @netphys.bsky.social · May 16

"These findings challenge the traditional brain-centric view of reward processing, supporting a more unified and integrated model in which gut-derived and vagus-mediated interoceptive signals are pivotal in intrinsically shaping motivation and reinforcement."

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · May 15

The gut-brain vagal axis governs mesolimbic dopamine dynamics and reward events https://www.biorxiv.org/content/10.1101/2025.05.12.653303v1

Reposted by Javeria Hashmi

Peter Kok @peterkok.bsky.social · May 15

Looking forward to #VSS2025! On the first day, @dotproduct.bsky.social sky.social will be presenting a poster on how predictions embedded in alpha oscillations modulate perception of noisy stimuli. Come one, come all! Poster 16.322, Friday 3-5pm, Banyan Breezeway. #neuroskyence #visionscience

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Reposted by Javeria Hashmi

Mariam Aly @mariamaly.bsky.social · May 13

When you successfully anticipate future events, what happens to your ability to encode the present? 🤔

Successful prediction increases the likelihood of successful encoding. We speculate about how switching between distinct encoding & prediction states can produce this effect.
osf.io/preprints/ps...

OSF

osf.io

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Reposted by Javeria Hashmi

Hugo Spiers @hugospiers.bsky.social · May 15

Impressive study in @nature from my colleague Marcus Stephenson-Jones at UCL in the @sainsburywellcome.bsky.social

www.nature.com/articles/s41...

Dopaminergic action prediction errors serve as a value-free teaching signal - Nature

Dopaminergic action prediction error signals are used by mice as a value-free teaching signal to reinforce stable sound–action associations in the tail of the striatum.

www.nature.com

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Javeria Hashmi @netphys.bsky.social · May 12

Indian paper by Arnab Barik lab on chronic pain mechanisms just published in the PAIN journal.

journals.lww.com/pain/fulltex...

Converging inputs compete at the lateral parabrachial... : PAIN

areas is a behavioral coping mechanism and it is sensitized in chronic pain. Hence, we have focused on delineating the brain circuits mediating licking in mice with chemotherapy-induced peripheral neu...

journals.lww.com

Reposted by Javeria Hashmi

John Holbein @johnholbein1.bsky.social · May 6

a little pick me up lol for the academics in the room

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Reposted by Javeria Hashmi

Wonder of Science @wonderofscience.bsky.social · May 7

These boxes are not moving. A mind-bending optical illusion by Japanese artist Jagarikin.

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Javeria Hashmi @netphys.bsky.social · May 2

Amazing talks by Katie Birnie and Yves Deconninck @canadianpain.bsky.social annual meeting. #canadianpain2025

Javeria Hashmi @netphys.bsky.social · Apr 29

CANADA!!!

Reposted by Javeria Hashmi

Toshi Furukawa @toshi-frkw.bsky.social · Apr 23

Published today in Nature Medicine. In one of the world’s largest RCTs of its kind (n=3,936), a smartphone app teaching 5 key cognitive-behavioral therapy skills improved subthreshold depression—and the effects lasted 6 months.

www.nature.com/articles/s41...

Cognitive behavioral therapy skills via a smartphone app for subthreshold depression among adults in the community: the RESiLIENT randomized controlled trial - Nature Medicine

A trial that used a master randomized design found that the skills commonly found in smartphone-based cognitive behavioral therapy, when tested alone or in combination with behavioral activation, were...

www.nature.com

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Javeria Hashmi @netphys.bsky.social · Apr 22

Spontaneous pain dynamics characterized by stochasticity in neural recordings of awake humans with chronic pain.

"during periods of higher pain states, we observed enhanced functional connectivity between the examined hub structures and the prefrontal cortex."
journals.lww.com/pain/abstrac...

Spontaneous pain dynamics characterized by stochasticity in ... : PAIN

ocal field potentials (LFPs) from pain-processing hub structures, including the ventral posteromedial nucleus of the thalamus, subgenual cingulate cortex, and periventricular and periaqueductal gray, ...

journals.lww.com