Objective To determine whether a machine learning model of voxel level [18f]fluorodeoxyglucose positron emission tomography (PET) data could predict progressive supranuclear palsy (PSP) pathology, a...

Imagine that malignant brain tumors are not the unbridled chaos of unchecked growth we think they are, but they are actually communicating with brain cells i...

Nature Reviews Neurology, Published online: 01 May 2025; doi:10.1038/s41582-025-01091-wPlasma biomarker tests for Alzheimer disease are becoming increasingly reliable, which enables implementation in clinical settings in which cerebrospinal fluid analysis and PET scans are unavailable. However, a new study shows that some patients have discordant plasma and PET biomarker results. Clinicians need clear guidance to identify and manage patients who do not fit into standard clinical or biological categories.

Germline sequence variations that predispose to cancer are common in people with central nervous system tumors, and neurologists should have a low thresho…

Treatment for individuals with neurofibromatosis type 1, a complex disease with variabilities in presentation and disease course, requires a multidiscipli…

Objective To implement parallel transmit (pTx) 7T magnetic resonance imaging (MRI) in the pre-surgical evaluation of 3T-negative patients with drug-resistant focal epilepsy, and to compare quality t...

Objective Parkinson's and Huntington's diseases are characterized by progressive neuronal loss. Previous studies using human postmortem tissues have shown the impact of neurodegenerative disorders o...