James Olzmann
@olzmannlab.bsky.social
Professor of Molecular Therapeutics and Metabolic Biology at UC Berkeley; Departments of Molecular & Cell Biology and Nutritional Sciences & Toxicology. Lipid droplets, ferroptosis, ubiquitin, drug development.
Thanks for the shout out, Jeremy!! Awesome to be on this list with all these lipid all star papers! ⭐️
January 6, 2026 at 3:15 AM
Thanks for the shout out, Jeremy!! Awesome to be on this list with all these lipid all star papers! ⭐️
Reposted by James Olzmann
15. And second, also from @olzmannlab.bsky.social, an ER chloride channel pushes LD formation toward the cytosol vs. nucleoplasm and affects nuclear pore complex assembly in @biorxiv-cellbio.bsky.social www.biorxiv.org/content/10.1...
CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly
Imbalances in lipid storage and secretion lead to the accumulation of hepatocyte lipid droplets (LDs) (i.e., hepatic steatosis). Our understanding of the mechanisms that govern the channeling of hepat...
www.biorxiv.org
January 5, 2026 at 2:48 PM
15. And second, also from @olzmannlab.bsky.social, an ER chloride channel pushes LD formation toward the cytosol vs. nucleoplasm and affects nuclear pore complex assembly in @biorxiv-cellbio.bsky.social www.biorxiv.org/content/10.1...
Reposted by James Olzmann
14. Two studies that reshape thinking about lipid droplets biology. First, lipid peroxidation can occur to neutral lipids inside the core of LDs, with protective mechanisms revealed, from @mikelangelipid.bsky.social and @olzmannlab.bsky.social in @natcellbio.nature.com www.nature.com/articles/s41...
FSP1-mediated lipid droplet quality control prevents neutral lipid peroxidation and ferroptosis - Nature Cell Biology
Lange et al. identify a lipid droplet quality control pathway in which FSP1 safeguards stored neutral lipids from lipid peroxidation, thereby preventing the induction of ferroptosis.
www.nature.com
January 5, 2026 at 2:48 PM
14. Two studies that reshape thinking about lipid droplets biology. First, lipid peroxidation can occur to neutral lipids inside the core of LDs, with protective mechanisms revealed, from @mikelangelipid.bsky.social and @olzmannlab.bsky.social in @natcellbio.nature.com www.nature.com/articles/s41...
Congrats! Looking forward to digging into this important review! 🤩
August 18, 2025 at 6:30 PM
Congrats! Looking forward to digging into this important review! 🤩