James Olzmann
@olzmannlab.bsky.social
2K followers
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87 posts
Professor of Molecular Therapeutics and Metabolic Biology at UC Berkeley; Departments of Molecular & Cell Biology and Nutritional Sciences & Toxicology. Lipid droplets, ferroptosis, ubiquitin, drug development.
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Reposted by James Olzmann
Reposted by James Olzmann
Reposted by James Olzmann
James Olzmann
@olzmannlab.bsky.social
· Aug 18
Reposted by James Olzmann
Ubellacker Lab
@ubellackerlab.bsky.social
· Aug 18
Reposted by James Olzmann
Reposted by James Olzmann
Reposted by James Olzmann
Liana Lareau
@lianafaye.bsky.social
· Aug 7
Protein language models reveal evolutionary constraints on synonymous codon choice
Evolution has shaped the genetic code, with subtle pressures leading to preferences for some synonymous codons over others. Codons are translated at different speeds by the ribosome, imposing constrai...
www.biorxiv.org
James Olzmann
@olzmannlab.bsky.social
· Aug 7
Fourteen Visionary Scientists Named 2025 ASCB Fellows - ASCB
The American Society for Cell Biology (ASCB) is proud to announce the election of 14 outstanding scientists as 2025 ASCB Fellows—a prestigious honor recognizing their exceptional contributions to cell...
www.ascb.org
Reposted by James Olzmann
Reposted by James Olzmann
James Olzmann
@olzmannlab.bsky.social
· Aug 6
James Olzmann
@olzmannlab.bsky.social
· Aug 6
Riboflavin metabolism shapes FSP1-driven ferroptosis resistance
Membrane protection against oxidative insults is achieved by the concerted action of glutathione peroxidase 4 (GPX4) and endogenous lipophilic antioxidants such as ubiquinone and vitamin E. Deficienci...
www.biorxiv.org
James Olzmann
@olzmannlab.bsky.social
· Aug 6
Vitamin B2 metabolism promotes FSP1 stability to prevent ferroptosis
Ferroptosis, a regulated form of cell death driven by excessive lipid peroxidation, has emerged as a promising therapeutic target in cancer. Ferroptosis suppressor protein 1 (FSP1) is a critical regul...
www.biorxiv.org
James Olzmann
@olzmannlab.bsky.social
· Aug 2
Reposted by James Olzmann