Kat Mayer-Barber,PhD
@mayerbarber.bsky.social
5.7K followers 1.3K following 92 posts
Cellular mucosal immunologist- lung- 🫁 innate immunity and inflammtion @IRP/NIAID/NIH - views my own https://www.niaid.nih.gov/research/katrin-d-mayer-barber-dr-rer-nat-phd
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mayerbarber.bsky.social
Best #Nikolaus 🎅! Our paper on how the 🫁 microenvironment can shape #innate immunity against #viruses is out @sciimmunology.bsky.social This was a herculean effort brilliantly led by @pauljbaker.bsky.social who singlehandedly established the model in the lab during the pandemic. 🧪 #Immunosky 1/9
Graphical summary of our paper.  In mice, prior lower airway exposure to diverse inflammatory stimuli, including chronic bacterial infections such as M. tuberculosis, acute bacterial infections such as pulmonary S. aureus, viral infections such as Influenza A, type-II allergic responses such as the OVA-Alum model, activation of pulmonary TLR9 by CpG or pulmonary TLR1/2 by Pam3CSK4
 leads to reduced viral burden upon subsequent infection with SARS-CoV-2 (SCV2). (2) This SCV2 restriction occurs prior to induction of SCV2-specific adaptive immune responses 
and is mediated through innate immune responses, including the induction of IFN-I, TNFα and IL-1 and sustained changes to the TRM (Tissue resident macrophage) cellular 
compartment and the pulmonary epithelium. (3) Innate cytokine and TLR signaling to both recruited immune cells and the pulmonary epithelium creates a microenvironment in the 
lung that limits early replication of SCV2. IFN-I signaling to pulmonary ECs (epithelial cells) increases expression of interferon-stimulated genes, that likely cell-intrinsically limit viral
 replication. TNF- or IL-1 suppress SCV2 independently of IFN-I signaling. TNF acts exclusively through radio-resistant cell types such as the lung epithelium, whereas IL-1 affords 
control both direct and indirectly, through either stromal and hematopoietic cell types, to restrict overall early SCV2 burden.
Reposted by Kat Mayer-Barber,PhD
jkpfeiff.bsky.social
Faculty search announcement 2025: Tenure-Track Assistant Professor in Microbiology at UT Southwestern. We seek candidates working in microbial pathogenesis (some preference may be given to bacterial pathogens). Come join our community! (1/5) www.utsouthwestern.edu/departments/...
Department members sit at a very long table in the hallway eating a pre-Thanksgiving potluck feast.
Reposted by Kat Mayer-Barber,PhD
hindhussein.bsky.social
Hello everyone! I am a postdoc in mucosal immunology and I am looking for new postdoc position in Europe! I know a lot about gut mast cells, but also CD4 T cells and type 2/3 immunity in general. I've worked with single cell sequencing and neuroimmune interactions. Feel free to share! Thank you! ♥️🥼👩‍🔬
Reposted by Kat Mayer-Barber,PhD
khadershabaana.bsky.social
UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
Reposted by Kat Mayer-Barber,PhD
khadershabaana.bsky.social
Dear #microbiology and #immunology community- I took a break from social media after I deleted my Twitter account, but am back here. Please help me rebuild my community by following me and amplifying this message- I will follow you back. Thank you and I look forward to our many interactions!
Reposted by Kat Mayer-Barber,PhD
asm.org
ASM @asm.org · 13d
Since the late 19th century, microbiologists have relied on agar and its derivatives for growing and separating microbes. However, how many of us really know the story of how this ingredient changed science? The remarkable story of Fanny Angelina Hesse youtu.be/qyTjqIKTQLo
Fanny Angelina Hesse and the Discovery of Agar
YouTube video by American Society for Microbiology
youtu.be
Reposted by Kat Mayer-Barber,PhD
mjafreeman.bsky.social
Starter packs are still valuable but there is now a mature set of communities @bsky.app

So maybe for the last time (unless things change)

An encyclopaedia of starter packs relevant to 'mechanistic' biomedical science (>100 now!)...

...including collective nouns

docs.google.com/spreadsheets...
@mjafreeman.bsky.social's encyclopedia of Bluesky starter packs for 'mechanistic' biologists
docs.google.com
mayerbarber.bsky.social
This is absolutely brilliant🤩.
Finding the right buffer set that you can use across most all #FACS needs… And at a fraction of cost… Love it👇🏻
Kudos to @labliston.bsky.social to dedicate time and effort to this….
labliston.bsky.social
For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper?

You got it:
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...
currentprotocols.onlinelibrary.wiley.com
Reposted by Kat Mayer-Barber,PhD
labliston.bsky.social
Just take a look. The Foxp3 fix/perm kit is good for TFs, but kills endogenous GFP. The eBio preserves GFP, but is incomplete at allowing TF staining. Burton's Best Buffer is as good as the best under all conditions (except phospho-flow), and preserves dye integrity too.

Plus it is dirt cheap. 🎤
Reposted by Kat Mayer-Barber,PhD
labliston.bsky.social
For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper?

You got it:
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...
currentprotocols.onlinelibrary.wiley.com
mayerbarber.bsky.social
I am biased 😉, but this is an amazing PI and an amazing person, check out this opportunity #immunosky #TB
danbarberphd.bsky.social
We are looking to hire post-docs to work on T cell responses to M. tuberculosis infection using murine and NHP models. If you know T cells and wanna work on the top global infectious killer check us out. BSL3 experience not required. The NIH intramural program in Bethesda MD is an amazing place!
Reposted by Kat Mayer-Barber,PhD
itaiyanai.bsky.social
Have you heard about the Night Science Podcast, where we talk about the actual creative process of doing science? We explore this with discussions with brilliant scientists & also philosophers and artists, to figure out the tricks of the creative scientific trade.
podcasts.apple.com/us/podcast/n...
Reposted by Kat Mayer-Barber,PhD
lozanzi.bsky.social
#InterferonPower! Thrilled for our latest work @cp-cell.bsky.social! With @danielboehmer.bsky.social, we dug into tons of papers & created what we hope will be a go-to resource for immunologists & non-immunologist about type I, II, III (& IV😉) #interferons! Free👉 authors.elsevier.com/a/1leKGL7PXu...
mayerbarber.bsky.social
Congratulations on this important finding! Will perhaps be relevant in other pathologies where clinically sex shows differences in outcomes.
Reposted by Kat Mayer-Barber,PhD
infectiousdz.bsky.social
Ah this is interesting: "At the genetic crossroads of Leishmania: Emerging hybrids reshaping disease patterns"
Mobility of people & vectors + climate & environmental change = rise in hybrid infections

Already happening with leish—new disease patterns emerging, with hundreds of cases in Turkey alone
At the genetic crossroads of Leishmania: Emerging hybrids reshaping disease patterns
journals.plos.org
Reposted by Kat Mayer-Barber,PhD
maxplanck.de
Director at Max Planck - a unique position! The Open Call for Expressions of Interest in Max Planck Directorships is open now and can be submitted by the 31st of October 2025. ➡️ mpg.de/directors - Please share the Open Call among potential candidates.
Open Call for Expressions of Interest in Max Planck Directorships:
Expressions of interest can be submitted until 31 October 2025.
mayerbarber.bsky.social
What a wonderful meeting! Thanks to @olzmannlab.bsky.social and the whole community for being so welcoming.🙏🏻
olzmannlab.bsky.social
The first FASEB Ferroptosis conference! ✔️ Thank you to my co-organizer Scott Dixon, our sponsors, and the whole #Ferroptosis community for showing up and making this such a wonderful meeting! 🤩 ❤️
Reposted by Kat Mayer-Barber,PhD
brentstockwell.bsky.social
Thanks to James Olzmann and Scott Dixon for organizing a fantastic #faseb #ferroptosis meeting in Scottsdale AZ! Lots of great science as ferroptosis continues to impact diverse biology and diseases. Can’t wait for the next one! @olzmannlab.bsky.social
Reposted by Kat Mayer-Barber,PhD
Reposted by Kat Mayer-Barber,PhD
braithwaiteat.bsky.social
Stimulating immune cells in vitro is a common experimental lab model. We profiled 150K blood immune cells treated with 11 different stimuli to compare the effects. The data are freely available for researchers. See the preprint for our findings and to access the data 🧪 doi.org/10.1101/2025...
Reposted by Kat Mayer-Barber,PhD
pamelialim.bsky.social
I’m so happy for my first post on Bluesky to be introducing my first 1st author paper! We show that alveolar macrophage inflammatory cytokine production to low dose LPS is enhanced by IFN-b due to lack of c-Maf/IL10 production. Download, share, and support science!! academic.oup.com/jimmunol/art...
Absence of c-Maf and IL-10 enables type I IFN enhancement of innate responses to LPS in alveolar macrophages
Abstract. Alveolar macrophages (AMs) are lung-resident myeloid cells and airway sentinels for inhaled pathogens and environmental particles. While AMs can
academic.oup.com
Reposted by Kat Mayer-Barber,PhD
lauraamike.bsky.social
It's seem like arginine is emerging as a major host cue. So we wrote an IAI minireview on how arginine levels vary between host tissues and affect microbial behavior.

The review is online today!
journals.asm.org/doi/epdf/10....

@brookeeryan3.bsky.social

#microsky
Known effects of arginine on Gram-positive and Gram-negative behavior