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Reposted by William Wade

Emmanuele Severi @emmseveri.bsky.social · 16d

www.biorxiv.org/content/10.1...

#microsky but feels more like Horrible Histories!

The oral microbiome of King Richard III of England

Metagenomic investigation of archaeological dental calculus has provided insights into the changing oral health, disease, and diet of past human societies, but little is known about the oral microbiot...

www.biorxiv.org

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Reposted by William Wade

Emmanuele Severi @emmseveri.bsky.social · Sep 5

www.jbc.org/article/S002...

#microsky #sialic acid

Interesting story, the starting Q v. important

Sialic acid identity modulates host tropism of sialoglycan-binding viridans group streptococci

Microbial interactions with multiple species may expand the range of potential hosts, supporting both pathogen reservoirs and zoonotic spillover. Viridans group streptococci interact with host cells b...

www.jbc.org

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Reposted by William Wade

Emmanuele Severi @emmseveri.bsky.social · Aug 22

www.nature.com/articles/s41...

#microsky

Discovery of a widespread chemical signalling pathway in the Bacteroidota - Nature

The N-acyl-cyclolysine system regulates the expression of co-localized operons encoding diverse secreted molecules in Bacteroidota.

www.nature.com

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Reposted by William Wade

DEEMteam_Orsay @deemteam.bsky.social · Jun 17

📣 We are proud of the publication of the second paper of @bbaker24.bsky.social PhD thesis. In collaboration with friends in Halifax we have studied the difficult question of the phylogeny of the DPANN archaea, composed of several phyla of highly reduced, fast-evolving epiparasites 🧵

rdcu.be/erkkU

Phylogenomic analyses indicate the archaeal superphylum DPANN originated from free-living euryarchaeal-like ancestors

Nature Microbiology - Phylogenetic reconstructions with conserved protein markers from the 11 known DPANN phyla reveal their monophyletic placement within the Euryarchaeota.

rdcu.be

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William Wade @oralmolecol.bsky.social · Jun 17

Don’t think much of the standard of English at that school if they say “heart-wrenching”. It’s “heart-rending” or “gut-wrenching”!

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Reposted by William Wade

Glen Dsouza @nonresidentdesi.bsky.social · Jun 13

Thrilled to share our new paper in @science.org describing our discovery that bacteria can switch from competitors to bonafide predators when resources run dry—arming nanoscale “spears” (T6SS) to stab & consume neighbours.

www.science.org/doi/10.1126/...

#MicroSKy #Microbiology

Antagonism as a foraging strategy in microbial communities

In natural habitats, nutrient availability limits bacterial growth. We discovered that bacteria can overcome this limitation by acquiring nutrients by lysing neighboring cells through contact-dependen...

www.science.org

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Reposted by William Wade

Christine Moissl-Eichinger @chmoei.bsky.social · Jun 3

📢 Big day for archaeal microbiology!

Today, we jointly shed light on the mysterious world of archaeal extracellular vesicles from human gut archaea - published in @natcomms.nature.com ‬ in parallel with our precious colleagues around @mkrupovic.bsky.social 🇦🇹🤝🇫🇷.

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Reposted by William Wade

Bat Bor @batbilegbor.bsky.social · Jun 3

Exciting progress! In our new preprint, we show that episymbiont Saccharibacteria can directly modulate epithelial immunity—a big step in understanding how these elusive microbes interact with the human host. Kudos to Deepak Chouhan and our amazing collaborators! www.biorxiv.org/content/10.1...

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Reposted by William Wade

thetranscendedman @atranscendedman.bsky.social · Dec 30

London study finds L. crispatus in the vaginal microbiome reduces inflammation by blocking harmful signals and activating anti-inflammatory pathways.

May protect against infections and preterm birth.

www.nature.com/articles/s41...

Lactobacillus crispatus S-layer proteins modulate innate immune response and inflammation in the lower female reproductive tract - Nature Communications

Here, the authors show that vaginal lactobacilli associated with optimal health interact selectively with a restricted subset of anti-inflammatory receptors through their Surface Layer Proteins, both ...

www.nature.com

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Reposted by William Wade

Seth Abramson @sethabramson.bsky.social · Mar 10

In a world of Matts, be a Derek.

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Reposted by William Wade

Richard Branson @richardbranson.bsky.social · Feb 20

President Zelenskyy has been one of the greatest leaders of our time, guiding Ukraine through the darkest period of its recent history, rising up to Russia’s unwarranted aggression, being an inspiration to the Ukrainian people and ensuring that Ukraine’s voice is heard on the world stage.

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William Wade @oralmolecol.bsky.social · Feb 19

Currant bun

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Reposted by William Wade

Nature Microbiology @natmicrobiol.nature.com · Feb 4

EDITORIAL: Ensuring rigour of low-biomass microbiome research

Read it here: www.nature.com/articles/s41...

#microsky #microbiomesky 🧪

Ensuring rigour of low-biomass microbiome research - Nature Microbiology

Determining whether human organs house a resident microbiome is challenging and the findings can be controversial. However, forging collaborations and careful study design can help overcome these issu...

www.nature.com

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Reposted by William Wade

Michael Wagner @michiwagner4.bsky.social · Dec 20

🌟 Exciting news! Our latest collaborative research with team @aarhusuni.bsky.social introduces pH-FISH, a novel technique combining pH ratiometry and FISH to simultaneously unravel microbial identity and local biofilm pH. 🔬 🧪 #MicroSky

link.springer.com/article/10.1...

#Microbiome #Biofilms

pH-FISH: coupled microscale analysis of microbial identity and acid–base metabolism in complex biofilm samples - Microbiome

Background Correlative structural and chemical imaging of biofilms allows for the combined analysis of microbial identity and metabolism at the microscale. Here, we developed pH-FISH, a method that co...

link.springer.com

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Reposted by William Wade

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · Dec 21

The Porphyromonas gingivalis lipid A 1-phosphatase LpxE has unique features and requires a functional type IX secretion system for its activity https://www.biorxiv.org/content/10.1101/2024.12.20.629629v1

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Reposted by William Wade

Jonathan Eisen @phylogenomics.bsky.social · Dec 20

An important read for all microbiome researchers #microbiomania www.theguardian.com/science/2024...

There’s little evidence of a ‘brain microbiome’ | Letter

Letters: Prof Mark Pallen, Dr Aimee Parker, Prof Nick Loman and Prof Alan Walker take issue with an article that discussed the existence of a brain microbiome and its impact on diseases

www.theguardian.com

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Reposted by William Wade

Tanja Pyhäjärvi @pyhatanja.bsky.social · Dec 16

Big news from Finnish publication forum. Almost all MDPI and Frontiers journals will be downgraded to level 0 and thus are not considered as properly peer reviewed trustworthy scientific journals.
julkaisufoorumi.fi/en/news/chan...

Changes to the classification

julkaisufoorumi.fi

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William Wade @oralmolecol.bsky.social · Dec 11

One of my favourite nerdy facts!

Reposted by William Wade

Bat Bor @batbilegbor.bsky.social · Dec 4

Excited to share our new preprint on the detailed investigation of Type 4 pili in epibiont oral Saccharibacteria! Led by Alex Grossman from our lab, and with Jun Liu (Yale), Jeff McLean (UW) and Xuesong He. Check it out: biorxiv.org/content/10.1...

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Reposted by William Wade

Zandra Fagernäs @zandraselina.bsky.social · Nov 25

The final chapter of my PhD thesis is finally out! Led by the brilliant Irina Velsko, we investigated if we can study past migrations in Oceania using #aDNA from archaeological dental calculus: www.nature.com/articles/s41...

Exploring the potential of dental calculus to shed light on past human migrations in Oceania - Nature Communications

Preservation of oral microbiome ancient DNA from Oceania is much better than human ancient DNA. The authors leverage this to demonstrate that oral microbial community composition in Oceania is not onl...

www.nature.com

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Reposted by William Wade

Katrina Ray @heykatray.bsky.social · Nov 15

This Perspective was a fun one to work on recently, examining the characteristics & role of small intestinal #microbiota, somewhat overlooked (tech difficulties in sampling, low microbial biomass) but important to health

www.nature.com/articles/s41...
🔓 rdcu.be/d0hBg

#GastroSky #Microsky