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Patrick Goymer @patrickgoymer.bsky.social · 57m

A new study in @plosone.org uses camera-trap data to show that male jaguars in Belize shift their ranges, overlap extensively, and lack exclusive territoriality, suggesting a scramble-competition mating system rather than strict mate monopoly.

Long-term spatial dynamics of jaguars in a high-density population

We assessed the socio-spatial dynamics of a jaguar population over 15 years using camera-trap data from Belize. Using ~4,000 independent detections of male jaguars, we documented and quantified range…

journals.plos.org

Patrick Goymer @patrickgoymer.bsky.social · 1h

A newly discovered TRPV5/6-like ion channel in the coral Pocillopora damicornis shows high calcium permeability, resistance to conventional inhibitors, and sensitivity to menthol, suggesting a role in coral calcification and potential links to bleaching responses.

journals.plos.org/plosone/arti...

A novel TRPV5/6-like channel from a scleractinian coral

The calcium regulation mechanisms that underlie skeleton formation in stony corals are poorly understood. In epithelial tissues from vertebrates, transient receptor potential vanilloids 5 and 6 (TRPV5...

journals.plos.org

Patrick Goymer @patrickgoymer.bsky.social · 2h

A new study in @plosone.org reveals that overexpression of FZD7, especially when combined with CD133, drives stem-cell–like features, impairs differentiation, and correlates with poor prognosis in human hepatocellular carcinoma.

Frizzled 7 drives amplification of cancer stem-cell subpopulations and the aggressiveness and poor differentiation of human hepatocellular carcinoma

FZD7 is one of the key players in the subset of WNT-TGFβ-activated hepatocellular carcinomas (HCC), but the consequences of its abnormal expression on hepatocarcinogenesis remain to be better…

journals.plos.org

Reposted by Patrick Goymer

PLOS Biology @plosbiology.org · 3h

Sleep is often only investigated from a single dimension. @bttyeo.bsky.social &co identify 5 sleep-biopsychosocial profiles that link self-reported #sleep patterns to variability in #health, #cognition & #lifestyle factors in 770 healthy young adults @plosbiology.org 🧪 plos.io/42tRXSc

Canonical correlation analysis reveals five sleep-biopsychosocial profiles (LCs). Scatter plots showing correlations between biopsychosocial and sleep canonical scores. Each dot represents a different participant. The inset shows the null distribution of canonical correlations obtained by permutation testing; note that the null distribution is not centered at zero. The dashed line indicates the actual canonical correlation computed for each LC. The distribution of sleep (top) and biopsychosocial (right) canonical scores is shown on rain cloud plots.

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Patrick Goymer @patrickgoymer.bsky.social · 3h

A new study in @plosone.org of a catch-neuter-vaccinate-release (CNVR) program in India found that it reduced mange, transmissible venereal tumours, and pregnancy in free-roaming dogs. Numbers of sterilised dogs observed increased but so did the population overall.

journals.plos.org/plosone/arti...

Changes in free-roaming dog population demographics and health associated with a catch-neuter-vaccinate-release program in Jamshedpur, India

India’s large free-roaming dog populations contribute to significant human health, environmental, and social challenges. Population management strategies, such as catch-neuter-vaccinate-release (CNVR)...

journals.plos.org

Patrick Goymer @patrickgoymer.bsky.social · 3h

A new study in @plosone.org shows significant age-related degeneration of outer hair cells, synapses, stria vascularis, and neurons in mice, and suggests that age-related hearing loss results from both oxidative stress and lifelong noise exposure.

journals.plos.org/plosone/arti...

Histopathological change of age-related hearing loss in female advance-aged CBA/CaJ mice

With the increase in the older population, the number of individuals with age-related hearing loss is also growing explosively. Therefore, there is an urgent need to identify the detailed pathology of...

journals.plos.org

Patrick Goymer @patrickgoymer.bsky.social · 3h

Using GPS tracking of 29 Falkland Steamer Ducks, a new study in @plosone.org found that home-range size, movement, foraging time and distance vary with breeding status and proximity to kelp beds, freshwater and human sites, highlighting kelp’s conservation value.

journals.plos.org/plosone/arti...

Home range and activity budget in the Falkland Steamer Duck (Tachyeres brachypterus)

The Falkland Islands support globally important populations of seabirds and coastal birds, underscoring their value for international conservation efforts. However, substantial knowledge gaps impede t...

journals.plos.org

Reposted by Patrick Goymer

Philip Ball @philipcball.bsky.social · 1d

2012 Nobel laureate John Gurdon has died. His work was central to both the development of animal cloning and the possibility of reprogramming cells to a different state. A giant of cell and developmental biology.
www.magd.cam.ac.uk/news/profess...

Professor Sir John Gurdon FRS (1933-2025) | Magdalene College

Magdalene College is deeply saddened to announce the death of Professor Sir John Gurdon FRS, who served as Master of the College from 1995 to 2002.

www.magd.cam.ac.uk

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Patrick Goymer @patrickgoymer.bsky.social · 1d

A new study in @plosone.org shows that invasive red-eared sliders in Illinois carry several pathogens without showing symptoms, thereby potentially acting as hidden carriers that pose a threat to native turtle populations through disease transmission.

journals.plos.org/plosone/arti...

Health assessment of non-native red-eared sliders (Trachemys scripta elegans) and their impact potential on native species

Red-eared sliders (RES; Trachemys scripta elegans) are a globally invasive species that can impact native chelonian populations through resource competition and disease introduction. In Cook County, I...

journals.plos.org

Reposted by Patrick Goymer

Kira Poskanzer @kiraposkanzer.bsky.social · 1d

Thanks to @ashleyingiosi.bsky.social for this thoughtful primer about our recent astrocyte/sleep paper!

PLOS Biology @plosbiology.org · 2d

Astrocytes help control #sleep & arousal. @ashleyingiosi.bsky.social explores a @plosbiology.org study showing that wake-promoting #histamine affects how #astrocytes respond to other signals, reducing awake time via astroglial histamine-1-receptors 🧪 Paper: plos.io/4gRj9Ap Primer: plos.io/47at1Sj

Astroglial H1Rs influence neuromodulatory integration and arousal.

How histamine modulates arousal via astrocytes was investigated in brain slices and mice with (left; green) and without (right; purple) histamine-1-receptor (H1R) expression in astrocytes of the primary visual cortex (V1). Panels below depict, from left to right, that H1R expression in V1 astrocytes: (1) attenuates astroglial calcium (Ca²⁺) responses to norepinephrine (NE) in brain slices; (2) suppresses astroglial Ca²⁺ events during wakefulness; (3) restricts the dynamic range of extracellular adenosine (Ado) around rapid eye movement (REM) sleep transitions (N, non-rapid eye movement sleep; W, wakefulness); and (4) reduces time spent in wakefulness.

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Patrick Goymer @patrickgoymer.bsky.social · 1d

Social and economic policies have left distinct genomic footprints on mezcal‑producing agaves in Mexico, reports a study in @plosone.org: Espadín shows evidence of clonal selection, while Bacanora has retained genetic diversity thanks to more permissive management.

journals.plos.org/plosone/arti...

How social and economic policies have affected the genome of mezcal agaves: The contrasting stories of Bacanora and Espadín

Plant domestication in Mesoamerica gave the world crops of global significance, such as maize, beans, squashes, cocoa, and cotton. Additionally, it has introduced species of regional economic importan...

journals.plos.org

Reposted by Patrick Goymer

Dan Routledge @droutledge.bsky.social · 2d

In our latest Editorial, PLOS Medicine Executive Editor Helen Lumbard and I call for the scientific community to tackle research fraud and paper mills head on by creating robust systems of data sharing and transparency 🧪 #PLOSMedicine #datasharing #openscience
@plos.org

📄➡️ plos.io/4nDKQ2c

Open science and transparency are our strongest tools in the fight against fraudulent publishing activities

PLOS Medicine Executive Editor, Helen Lumbard, and Senior Editor, Front Section, Daniel Routledge, call for the scientific community to tackle research fraud and paper mills head on by creating robust...

journals.plos.org

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Reposted by Patrick Goymer

PLOS Biology @plosbiology.org · 2d

Evolution of fungal mating systems: Study of #Cryptococcus & Kwoniella by @marcoacoelho.bsky.social @marciadavidpalma.bsky.social &co shows that MAT locus fusions & recombination suppression drive diversity of #SexualReproduction in #fungi @plosbiology.org 🧪 plos.io/479579M

Top: Micrographs showing hyphal filaments extending from colony peripheries in a sexual cross between CBS8507 and CBS10435 after 2 weeks of incubation on CMA and V8 pH 5 media, in the dark, at room temperature. Insets depict two types of basidia: globose (a–c) and lageniform (b–d). Black arrows indicate clusters of cells emerging near basidia (either at the surface or embedded), scored as potential meiotic progeny (basidiospores). Bottom: Schematic representation of key chromosomal rearrangements and evolutionary events underlying transitions from tetrapolar to bipolar and pseudobipolar mating configurations. The phylogenetic tree highlights inferred changes in MAT locus structure, with color-coded branches representing both extant and reconstructed MAT configurations. Dashed lines indicate unresolved phylogenetic relationships among clades A, B, and C. Insets summarize distinct evolutionary stages, including: the ancestral organization with unlinked and compact P/R and HD loci (1); small-scale expansion of the P/R locus in Kwoniella (2); two independent large-scale expansions of the P/R locus in Cryptococcus (5); relocation of P/R and HD loci onto the same chromosome in Kwoniella resulting in either pseudobipolar (3) or fused (4) MAT configurations; and independent HD-P/R fusion events with HD gene loss in Cryptococcus pathogens and Cryptococcus sp. 3 (6). These transitions illustrate the diverse pathways by which chromosomal rearrangements (CRs) have shaped MAT locus architecture in these fungal lineages.

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Patrick Goymer @patrickgoymer.bsky.social · 2d

The 2025 @nobelprize.bsky.social in Physiology or Medicine goes to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi for their work on the identification of regulatory T cells and FOXP3.

www.nobelprize.org/uploads/2025...

www.nobelprize.org

Reposted by Patrick Goymer

The Royal Society @royalsociety.org · 2d

Are you an oceanographer or marine biologist with an interest in marine biodiversity and climate change? Our upcoming scientific meeting will look at #ClimateChange and #BiodiversityLoss linkages in ocean ecosystems:

royalsociety.org/science-even...

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Patrick Goymer @patrickgoymer.bsky.social · 4d

A new study in @plosone.org shows that a rescued female red panda released into the wild had different movement and habitat use from wild individuals at first but adjusted over ~60 days, suggesting a transitional period is needed for post-release acclimation.

Study on the environmental adaptation characteristics of red panda release into the wild

Animals undergo a cognitive process when exposed to novel environments, which plays a crucial role in their ability to identify optimal habitats and support long-term survival. We conducted an…

journals.plos.org

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Patrick Goymer @patrickgoymer.bsky.social · 5d

Sarcoptic mange threatens wombat populations, but a new study in @plosone.org shows that repeated moxidectin treatment via burrow-flap systems can temporarily eliminate the disease in high-density populations, with retreatment needed after approximately 20 months.

journals.plos.org/plosone/arti...

Treatment and monitoring of a high-density population of bare-nosed wombats for sarcoptic mange

Sarcoptes scabiei causes a fatal disease (mange) in bare-nosed wombats (BNWs) (Vombatus ursinus) across their range and can threaten isolated populations with extinction. Repeated dosing of moxidectin...

journals.plos.org

Patrick Goymer @patrickgoymer.bsky.social · 5d

A new study in @plosone.org describes two strains of Gordonia alkanivorans on grape leaves that can break down the wildfire-caused smoky-taste in wine, and identifies the guaA cytochrome P450 gene as essential for this.

www.smithsonianmag.com/smart-news/w...

journals.plos.org/plosone/arti...

Wildfires Are Ruining Your Favorite Wines. These Bacteria Might Be Able to Help

Microbes already growing on grape plants may help neutralize one of the compounds responsible for wildfire-exposed grapes' off-putting flavors, new research suggests

www.smithsonianmag.com

Patrick Goymer @patrickgoymer.bsky.social · 5d

Live streaming now, the EAT-Lancet Commission 2025 report: www.youtube.com/live/4ofJYRz...
(also report here: www.thelancet.com/journals/lan...

The 2025 EAT-Lancet Commission Livestream

YouTube video by EAT

www.youtube.com

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Reposted by Patrick Goymer

PLOS One @plosone.org · 7d

PLOS ONE Academic Editor, epidemiologist, and public health professional Dr. Zinia T. Nujum discusses this year’s #WorldRabiesDay theme “Act Now: You, Me, Community” in this recent EveryOne blog: plos.io/46upkGX

A Call to Action on World Rabies Day and Beyond - EveryONE

On World Rabies Day, PLOS One Academic Editor Dr. Zinia T. Nujum shares her perspectives on this year’s theme, “Act Now: You…

everyone.plos.org

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Patrick Goymer @patrickgoymer.bsky.social · 6d

As we mourn Jane Goodall, this @nature.com article explores three ways in which she changed science:

1. Altering the way we view both other primates and ourselves
2. Inspiring generations of women scientists
3. Communicating science in a way that engaged the public

www.nature.com/articles/d41...

Jane Goodall’s legacy: three ways she changed science

The primatologist challenged what it meant to be a scientist.

www.nature.com

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Reposted by Patrick Goymer

IPBES @ipbes.net · 6d

RIP #JaneGoodall - one of the modern pioneers of profound interconnections between people, animals and ecosystems. Her life was lived through science, compassion and tireless advocacy for the multiple values of nature - leaving a legacy that will endure for people and planet.

The Associated Press @apnews.com · 6d

BREAKING: Jane Goodall, the conservationist renowned for chimpanzee research and environmental advocacy, has died.

Jane Goodall, conservationist renowned for chimpanzee research and environmental advocacy, has died

Jane Goodall, the conservationist renowned for her groundbreaking chimpanzee field research and globe-spanning environmental advocacy, has died. She was 91.

bit.ly

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Reposted by Patrick Goymer

PLOS @plos.org · 7d

When public health decisions affect vulnerable communities, research has a role to play.

Evidence-based insights can help illuminate the impact, inform inclusive responses, and support those facing barriers to care, especially LGBTQ+ youth.

🔗 plos.io/3WeJMpg

Suicide Prevention Awareness Month - The Official PLOS Blog

In a recent post on Scholarly Kitchen, three writers shared personal stories expressing concern over the White House’s decision to eliminate federal…

theplosblog.plos.org

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Patrick Goymer @patrickgoymer.bsky.social · 7d

A new study in @plosone.org critically reanalyzes published data and concludes that the previously suggested extreme two‑fold genome size variation in Spodoptera frugiperda is an overestimate, with actual genome sizes remaining relatively stable around 380–390 Mb.

journals.plos.org/plosone/arti...

Is the extreme within-population genome size variation real in Spodoptera frugiperda?

Genome size variation is one of the main topics in evolutionary genomics. Recent studies in Spodoptera frugiperda (Insect; Lepidoptera) reported very striking results, including large genome size diff...

journals.plos.org

Reposted by Patrick Goymer

IPBES @ipbes.net · 7d

Breaking!

In a new paper published in @plos.org, former @ipbes.net Executive Secretary @annelarigauderie.bsky.social and #TransformativeChange Assessment co-chairs explore how stopping biodiversity loss is contingent on transformative change.🌍🏡

🧪 https://plos.io/4oZQEUI @lucasgaribaldi.bsky.social

Underlying causes, indirect drivers and direct drivers of biodiversity loss and nature’s decline.

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