@piotrnowak75.bsky.social
Reposted
Is It Time to Use Single-Dose Amphotericin B for HIV-Related Cryptococcal Meningitis in the USA?
The answer is yes!
doi.org/10.1001/jama...
The answer is yes!
doi.org/10.1001/jama...
Single-Dose Amphotericin B for HIV-Related Cryptococcal Meningitis
Cryptococcal meningitis remains a life-threatening opportunistic infection among people with advanced HIV, even in high-resource settings. For decades, the standard induction regimen in the United Sta...
doi.org
January 21, 2026 at 7:57 PM
Is It Time to Use Single-Dose Amphotericin B for HIV-Related Cryptococcal Meningitis in the USA?
The answer is yes!
doi.org/10.1001/jama...
The answer is yes!
doi.org/10.1001/jama...
Reposted
Persistent seronegativity and absence of intact proviruses despite prolonged initial viremia in early-treated perinatal HIV infection
✅ Just Accepted
🔗 https://bit.ly/3NlZhKN
✅ Just Accepted
🔗 https://bit.ly/3NlZhKN
January 15, 2026 at 10:15 PM
Persistent seronegativity and absence of intact proviruses despite prolonged initial viremia in early-treated perinatal HIV infection
✅ Just Accepted
🔗 https://bit.ly/3NlZhKN
✅ Just Accepted
🔗 https://bit.ly/3NlZhKN
Reposted
📚We launched ESCMID Media last year, where our members can watch everything from past webinars to sessions from #ESCMIDGlobal and other conferences!
👀Explore it now: https://media.escmid.org/
#IDSky #clinmicro
👀Explore it now: https://media.escmid.org/
#IDSky #clinmicro
January 11, 2026 at 10:10 AM
📚We launched ESCMID Media last year, where our members can watch everything from past webinars to sessions from #ESCMIDGlobal and other conferences!
👀Explore it now: https://media.escmid.org/
#IDSky #clinmicro
👀Explore it now: https://media.escmid.org/
#IDSky #clinmicro
Reposted
Antimicrobial in critically Ill adult patients receiving #ECMO: challenges, evidence, and future directions
💉 PK/PD concepts & considerations
🧫 antibacterials
🍄 antifungals
🦠 antivirals
🩺 management recommendations: dose optimization, challenges/recommendations, ABT stewardship
🔓 bit.ly/45vjrbt
💉 PK/PD concepts & considerations
🧫 antibacterials
🍄 antifungals
🦠 antivirals
🩺 management recommendations: dose optimization, challenges/recommendations, ABT stewardship
🔓 bit.ly/45vjrbt
December 28, 2025 at 6:32 PM
Antimicrobial in critically Ill adult patients receiving #ECMO: challenges, evidence, and future directions
💉 PK/PD concepts & considerations
🧫 antibacterials
🍄 antifungals
🦠 antivirals
🩺 management recommendations: dose optimization, challenges/recommendations, ABT stewardship
🔓 bit.ly/45vjrbt
💉 PK/PD concepts & considerations
🧫 antibacterials
🍄 antifungals
🦠 antivirals
🩺 management recommendations: dose optimization, challenges/recommendations, ABT stewardship
🔓 bit.ly/45vjrbt
Reposted
A phase 2 open label RCT of weekly Islatravir + Lenacapravir in patients living with HIV combared B/F/TAF:
-Similar rate of viral suppression (VL<50)
-Similar effect on CD4 count
Likely one step closer to a weekly oral HIV med.
#IDSky
www.acpjournals.org/doi/10.7326/...
-Similar rate of viral suppression (VL<50)
-Similar effect on CD4 count
Likely one step closer to a weekly oral HIV med.
#IDSky
www.acpjournals.org/doi/10.7326/...
Once-Weekly Oral Islatravir Plus Lenacapavir Versus Daily Oral Bictegravir, Emtricitabine, and Tenofovir Alafenamide in Persons With HIV-1: A Phase 2 Randomized Study: Annals of Internal Medicine: Vol...
Background: Once-weekly oral islatravir plus lenacapavir (ISL+LEN) has the potential to address adherence challenges with daily HIV-1 treatment. Objective: To evaluate efficacy and safety of once-week...
www.acpjournals.org
December 22, 2025 at 11:50 PM
A phase 2 open label RCT of weekly Islatravir + Lenacapravir in patients living with HIV combared B/F/TAF:
-Similar rate of viral suppression (VL<50)
-Similar effect on CD4 count
Likely one step closer to a weekly oral HIV med.
#IDSky
www.acpjournals.org/doi/10.7326/...
-Similar rate of viral suppression (VL<50)
-Similar effect on CD4 count
Likely one step closer to a weekly oral HIV med.
#IDSky
www.acpjournals.org/doi/10.7326/...
Reposted
Anti-interferon-γ autoantibodies and indeterminate QuantiFERONⓇ-TB Gold Plus Assays
✅ Just Accepted
🔗 https://bit.ly/4a4CFYR
✅ Just Accepted
🔗 https://bit.ly/4a4CFYR
December 6, 2025 at 4:48 PM
Anti-interferon-γ autoantibodies and indeterminate QuantiFERONⓇ-TB Gold Plus Assays
✅ Just Accepted
🔗 https://bit.ly/4a4CFYR
✅ Just Accepted
🔗 https://bit.ly/4a4CFYR
Reposted
Human-to-Human Rabies Transmission via Solid Organ Transplantation from a Donor with Undiagnosed Rabies — United States, October 2024–February 2025
MMWR
A man died of donor-derived rabies after receiving a kidney transplant from a donor scratched by a skunk.
www.cdc.gov/mmwr/volumes... #TxID
MMWR
A man died of donor-derived rabies after receiving a kidney transplant from a donor scratched by a skunk.
www.cdc.gov/mmwr/volumes... #TxID
Human-to-Human Rabies Transmission via Solid Organ...
This report describes the public health response to a patient who died after transplantation with an organ from a donor with undiagnosed rabies.
www.cdc.gov
December 6, 2025 at 4:56 PM
Human-to-Human Rabies Transmission via Solid Organ Transplantation from a Donor with Undiagnosed Rabies — United States, October 2024–February 2025
MMWR
A man died of donor-derived rabies after receiving a kidney transplant from a donor scratched by a skunk.
www.cdc.gov/mmwr/volumes... #TxID
MMWR
A man died of donor-derived rabies after receiving a kidney transplant from a donor scratched by a skunk.
www.cdc.gov/mmwr/volumes... #TxID
Reposted
This is gold. Thank you!!
November 5, 2025 at 4:35 PM
This is gold. Thank you!!
Reposted
Long-Acting Cabotegravir/Rilpivirine for Treatment of HIV During Pregnancy: A Case Series
✅ Just Accepted
#IDSky
🔗 https://bit.ly/4hxXPjI
✅ Just Accepted
#IDSky
🔗 https://bit.ly/4hxXPjI
November 2, 2025 at 4:21 PM
Long-Acting Cabotegravir/Rilpivirine for Treatment of HIV During Pregnancy: A Case Series
✅ Just Accepted
#IDSky
🔗 https://bit.ly/4hxXPjI
✅ Just Accepted
#IDSky
🔗 https://bit.ly/4hxXPjI
Reposted
Sustained HIV suppression with co-formulated tenofovir disoproxil fumarate/lamivudine/dolutegravir in a person with transmitted dolutegravir resistance and pre-treatment resistance to lamivudine: a case report from HPTN 083
✅ Just Accepted
#IDSky
🔗 https://bit.ly/4oxIGRA
✅ Just Accepted
#IDSky
🔗 https://bit.ly/4oxIGRA
October 27, 2025 at 9:35 PM
Sustained HIV suppression with co-formulated tenofovir disoproxil fumarate/lamivudine/dolutegravir in a person with transmitted dolutegravir resistance and pre-treatment resistance to lamivudine: a case report from HPTN 083
✅ Just Accepted
#IDSky
🔗 https://bit.ly/4oxIGRA
✅ Just Accepted
#IDSky
🔗 https://bit.ly/4oxIGRA
Reposted
Female sex is protective against MASLD with clinically significant fibrosis in a large cross-sectional cohort of persons with HIV
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Female sex is protective against MASLD with clinically significant fibrosis in a large cross-sectional cohort of persons with HIV
Men are at higher risk for metabolic dysfunction-associated steatotic liver disease (MASLD) with clinically significant fibrosis (CSF) than pre-menopausal women, but data are lacking in persons with HIV (PWH).
bit.ly
October 26, 2025 at 12:21 AM
Female sex is protective against MASLD with clinically significant fibrosis in a large cross-sectional cohort of persons with HIV
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Reposted
Join Dr. John Williamson as he shares prelim results of a Phase 2 trial of an allosteric integrase inhibitor, pirmitegravir (STP0404). Patients with HIV infection received 1 of 2 doses, either 200mg or 400mg daily, which was well tolerated & demonstrated a meaningful virologic effect. #IDWeek2025
October 20, 2025 at 3:29 PM
Join Dr. John Williamson as he shares prelim results of a Phase 2 trial of an allosteric integrase inhibitor, pirmitegravir (STP0404). Patients with HIV infection received 1 of 2 doses, either 200mg or 400mg daily, which was well tolerated & demonstrated a meaningful virologic effect. #IDWeek2025
Reposted
October 19, 2025 at 6:16 PM
Reposted
#idweek2025 #idsky Dr Caskey what’s hot in hiv basic science
October 19, 2025 at 5:38 PM
#idweek2025 #idsky Dr Caskey what’s hot in hiv basic science
Reposted
New #IDSAGuidelines! IDSA has released updated evidence-based recommendations on the use of nirmatrelvir/ritonavir, remdesivir, and molnupiravir in adults with mild to moderate COVID-19: https://bit.ly/3W5IdtT
October 16, 2025 at 5:39 PM
New #IDSAGuidelines! IDSA has released updated evidence-based recommendations on the use of nirmatrelvir/ritonavir, remdesivir, and molnupiravir in adults with mild to moderate COVID-19: https://bit.ly/3W5IdtT
Reposted
Two or three? Clinical and proteomic perspectives on dolutegravir/lamivudine versus bictegravir/emtricitabine/tenofovir alafenamide as initial HIV treatment.
✅ Just Accepted
#IDSky
🔗 https://bit.ly/3KJ6vY7
✅ Just Accepted
#IDSky
🔗 https://bit.ly/3KJ6vY7
October 16, 2025 at 8:46 PM
Two or three? Clinical and proteomic perspectives on dolutegravir/lamivudine versus bictegravir/emtricitabine/tenofovir alafenamide as initial HIV treatment.
✅ Just Accepted
#IDSky
🔗 https://bit.ly/3KJ6vY7
✅ Just Accepted
#IDSky
🔗 https://bit.ly/3KJ6vY7
Reposted
Sometimes, the sodium content of antibiotics matters. Just last week, there was a CHF patient with pneumonia who wasn’t improving - It turns out that the culprit wasn’t infection severity; it was likely the sodium load from Zosyn (piperacillin–tazobactam). Check out our "fry scale."
October 13, 2025 at 2:08 PM
Sometimes, the sodium content of antibiotics matters. Just last week, there was a CHF patient with pneumonia who wasn’t improving - It turns out that the culprit wasn’t infection severity; it was likely the sodium load from Zosyn (piperacillin–tazobactam). Check out our "fry scale."
Reposted
Antiretroviral therapy intensification with dolutegravir and/or maraviroc did not affect HIV-1 cell-associated DNA, RNA, and 2-LTR circles over twelve weeks
✅ Just Accepted
#IDSky
🔗 https://bit.ly/46JYkDp
✅ Just Accepted
#IDSky
🔗 https://bit.ly/46JYkDp
October 14, 2025 at 5:26 PM
Antiretroviral therapy intensification with dolutegravir and/or maraviroc did not affect HIV-1 cell-associated DNA, RNA, and 2-LTR circles over twelve weeks
✅ Just Accepted
#IDSky
🔗 https://bit.ly/46JYkDp
✅ Just Accepted
#IDSky
🔗 https://bit.ly/46JYkDp
Reposted
Incidence and clinical outcomes of multiple viral infections after allogeneic haematopoietic cell transplantation
✅ Just Accepted
#IDSky
🔗 https://bit.ly/3VM3V60
✅ Just Accepted
#IDSky
🔗 https://bit.ly/3VM3V60
October 9, 2025 at 9:14 PM
Incidence and clinical outcomes of multiple viral infections after allogeneic haematopoietic cell transplantation
✅ Just Accepted
#IDSky
🔗 https://bit.ly/3VM3V60
✅ Just Accepted
#IDSky
🔗 https://bit.ly/3VM3V60
Reposted
How exercise promotes the immune system vs cancer, working through a gut bacteria metabolite
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...
October 2, 2025 at 6:56 PM
How exercise promotes the immune system vs cancer, working through a gut bacteria metabolite
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...
Reposted
Intact and Defective HIV Provirus Changes During Antiretroviral Therapy in People Treated during Acute or Chronic HIV Infection or as HIV Controllers
✅ Just Accepted
🔗 https://bit.ly/42F6EBV
✅ Just Accepted
🔗 https://bit.ly/42F6EBV
September 28, 2025 at 1:38 AM
Intact and Defective HIV Provirus Changes During Antiretroviral Therapy in People Treated during Acute or Chronic HIV Infection or as HIV Controllers
✅ Just Accepted
🔗 https://bit.ly/42F6EBV
✅ Just Accepted
🔗 https://bit.ly/42F6EBV
Reposted
Key findings from the U.S. Public Health Service's 2025 Guidelines for the Management of Occupational Exposure to HIV and Recommendations for PEP
The full guideline is available here: doi.org/10.1017/ice....
The full guideline is available here: doi.org/10.1017/ice....
September 15, 2025 at 8:59 PM
Key findings from the U.S. Public Health Service's 2025 Guidelines for the Management of Occupational Exposure to HIV and Recommendations for PEP
The full guideline is available here: doi.org/10.1017/ice....
The full guideline is available here: doi.org/10.1017/ice....
Reposted
