Chandra Saravanan
@pondicherryan.bsky.social
Experimental Biologist #glycotime #spatialbiology
Reposted by Chandra Saravanan
Everyone please read and act! 👇
ACTION ITEM-----ACTION ITEM
Implementation of Schedule F
This is what a lot of us have been worried about.
This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.
BUT THERE IS A COMMENT PERIOD...
1/n
Implementation of Schedule F
This is what a lot of us have been worried about.
This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.
BUT THERE IS A COMMENT PERIOD...
1/n
the word alert is in a purple circle
ALT: the word alert is in a purple circle
media.tenor.com
April 23, 2025 at 9:00 PM
Everyone please read and act! 👇
Reposted by Chandra Saravanan
Happy to share this new #glycotime work with collaborator Tony Wyss-Coray, led by grad student Sophia Shi, mucin loss at the BBB is associated with aging and cognitive decline, can be reversed by restoration with with gene therapy. Aging is a mucinopathy!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Glycocalyx dysregulation impairs blood–brain barrier in ageing and disease - Nature
Disruption of mucin-domain glycoprotein expression and function in the endothelial glycocalyx are associated with ageing and Alzheimer’s disease, leading to dysregulated blood–brain barrier function.
www.nature.com
February 26, 2025 at 9:58 PM
Happy to share this new #glycotime work with collaborator Tony Wyss-Coray, led by grad student Sophia Shi, mucin loss at the BBB is associated with aging and cognitive decline, can be reversed by restoration with with gene therapy. Aging is a mucinopathy!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Chandra Saravanan
Say what now?!
Happy to share this new #glycotime work with collaborator Tony Wyss-Coray, led by grad student Sophia Shi, mucin loss at the BBB is associated with aging and cognitive decline, can be reversed by restoration with with gene therapy. Aging is a mucinopathy!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Glycocalyx dysregulation impairs blood–brain barrier in ageing and disease - Nature
Disruption of mucin-domain glycoprotein expression and function in the endothelial glycocalyx are associated with ageing and Alzheimer’s disease, leading to dysregulated blood–brain barrier function.
www.nature.com
February 26, 2025 at 9:59 PM
Say what now?!
Reposted by Chandra Saravanan
A quick guide to protein glycosylation: 7 most importants questions about glycosylation answered in one short review
bit.ly/3Xis7xP
#glycotime
bit.ly/3Xis7xP
#glycotime
February 25, 2025 at 8:59 AM
A quick guide to protein glycosylation: 7 most importants questions about glycosylation answered in one short review
bit.ly/3Xis7xP
#glycotime
bit.ly/3Xis7xP
#glycotime
Reposted by Chandra Saravanan
slate.com/podcasts/wha...
I want you to imagine that your baby has been born with mysterious symptoms. A hospital data scientist is trying to figure it out with rare disease data from the CDC. But suddenly that information is deleted. Today’s show. With @jasonkoebler.bsky.social:
I want you to imagine that your baby has been born with mysterious symptoms. A hospital data scientist is trying to figure it out with rare disease data from the CDC. But suddenly that information is deleted. Today’s show. With @jasonkoebler.bsky.social:
Why Trump’s Data Purge is a Digital Book Burning
How reporters tracked the Trump administration's data purges in real time.
slate.com
February 9, 2025 at 11:56 AM
slate.com/podcasts/wha...
I want you to imagine that your baby has been born with mysterious symptoms. A hospital data scientist is trying to figure it out with rare disease data from the CDC. But suddenly that information is deleted. Today’s show. With @jasonkoebler.bsky.social:
I want you to imagine that your baby has been born with mysterious symptoms. A hospital data scientist is trying to figure it out with rare disease data from the CDC. But suddenly that information is deleted. Today’s show. With @jasonkoebler.bsky.social:
Reposted by Chandra Saravanan
Check it out! Another novel RNA modification - ADP-ribosylation - that was previously only known on proteins. A cousin to #glycoRNA 👏
www.nature.com/articles/s41...
www.nature.com/articles/s41...
February 6, 2025 at 7:38 PM
Check it out! Another novel RNA modification - ADP-ribosylation - that was previously only known on proteins. A cousin to #glycoRNA 👏
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Chandra Saravanan
Oncolytic virus (OV) therapy: recombinant Newcastle disease virus with porcine α1,3 galactosyltransferase (α1,3GT) gene triggers hyperacute rejection. Clinical trial showed a high rate (90.00%) of disease control and durable response.
tinyurl.com/3fx7aur8
#glycotime
tinyurl.com/3fx7aur8
#glycotime
Hyperacute rejection-engineered oncolytic virus for interventional clinical trial in refractory cancer patients
Recently, oncolytic virus (OV) therapy has shown great promise in treating malignancies. However, intravenous safety and inherent lack of immunity are…
tinyurl.com
January 27, 2025 at 11:25 AM
Oncolytic virus (OV) therapy: recombinant Newcastle disease virus with porcine α1,3 galactosyltransferase (α1,3GT) gene triggers hyperacute rejection. Clinical trial showed a high rate (90.00%) of disease control and durable response.
tinyurl.com/3fx7aur8
#glycotime
tinyurl.com/3fx7aur8
#glycotime
Reposted by Chandra Saravanan
1/
Hi 🦋! Did you know? Glycans—complex sugar structures—decorate almost every protein processed by the ER/Golgi. These N-glycans coat our cells, playing critical roles in cell interactions and immune processes. 🍬 Curious about how they vary? Let’s dive in! #GlycoTime
Hi 🦋! Did you know? Glycans—complex sugar structures—decorate almost every protein processed by the ER/Golgi. These N-glycans coat our cells, playing critical roles in cell interactions and immune processes. 🍬 Curious about how they vary? Let’s dive in! #GlycoTime
November 19, 2024 at 9:50 AM
1/
Hi 🦋! Did you know? Glycans—complex sugar structures—decorate almost every protein processed by the ER/Golgi. These N-glycans coat our cells, playing critical roles in cell interactions and immune processes. 🍬 Curious about how they vary? Let’s dive in! #GlycoTime
Hi 🦋! Did you know? Glycans—complex sugar structures—decorate almost every protein processed by the ER/Golgi. These N-glycans coat our cells, playing critical roles in cell interactions and immune processes. 🍬 Curious about how they vary? Let’s dive in! #GlycoTime
Reposted by Chandra Saravanan
I'm excited to rebuild this #science community over here on Bluesky! In honor of this clean slate, here's a repost of my favorite #epithelial cell building its brush border. @tyskalabactual.bsky.social
November 21, 2024 at 6:49 PM
I'm excited to rebuild this #science community over here on Bluesky! In honor of this clean slate, here's a repost of my favorite #epithelial cell building its brush border. @tyskalabactual.bsky.social