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Prof Paula Salgado @pssalgado.bsky.social · 1d

It was a fantastic talk and real pleasure to discuss a new collaboration with Mark! #microsky

CBCB Newcastle @cbcb-newcastle.bsky.social · 1d

It was great to have Mark visit us today. Many great science discussions and hopefully new collaborations to start!

Dr Katherine Duncan @kateduncan.bsky.social · 1d

Very exciting to have Prof Mark Blaskovich @medicalsciencesncl.bsky.social (hosted by @henrikstrahl.bsky.social) all the way from the University of Queensland, Australia to give a seminar on collaborative approaches to combat antimicrobial resistance #drugdiscovery #AMR #antibiotics

Reposted by Prof Paula Salgado

Cascales Lab @cascaleslab.bsky.social · 10d

Open position !!
Either at the Engineer or post-doctoral level, to work on filamentous phages. Collaboration between Laetitia Houot's group and Thierry Doan @thicoz.bsky.social.
To apply at the E level:
emploi.cnrs.fr/Offres/CDD/U...
To apply at the post-doc level:
emploi.cnrs.fr/Offres/CDD/U...

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Reposted by Prof Paula Salgado

Alexis Verger 🧬🧫🧪 @alexis-verger.cpesr.fr · 12d

Now published in @science.org

Predicting protein-protein interactions in the human proteome

www.science.org/doi/10.1126/...

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Reposted by Prof Paula Salgado

ESCMID @escmid.bsky.social · 12d

The ESCMID AMR Action Subcommittee has organised a series of online events leading up to #WAAW, 18 - 24 Nov 2025. These webinars cover topics under the theme of rethinking our response to #AMR in different ways. Learn more & register: ow.ly/46rb50X0L59

#IDSky #clinmicro

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Reposted by Prof Paula Salgado

Wiep Klaas Smits (ExpBac/CMAT) @smitslab.bsky.social · 15d

A targeted cell lysis mechanism facilitates toxin release in Clostridioides difficile www.biorxiv.org/content/10.1...

A targeted cell lysis mechanism facilitates toxin release in Clostridioides difficile

Clostridioides difficile infection is associated with the production of two large toxins, TcdA and TcdB. The toxins are encoded in a pathogenicity locus along with a phage-like holin protein, TcdE, th...

www.biorxiv.org

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Reposted by Prof Paula Salgado

Microbes in Health and Disease @mhd-newcastle.bsky.social · 15d

The Salgado group focuses on structural and functional characterisation of proteins involved in pathogenicity pathways in C. difficile. They are particularly interested in S-layer and sporulation proteins and their role in infection.

Follow @pssalgado.bsky.social

salgadolab.org

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Reposted by Prof Paula Salgado

Microbes in Health and Disease @mhd-newcastle.bsky.social · 15d

The Bolam lab uses a range of biochemical, microbiological, genetic and structural techniques to study the molecular mechanisms utilised by our resident gut bacteria to recognise, acquire and degrade complex glycans from both dietary and host sources.

Follow @dave-bolam.bsky.social

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Reposted by Prof Paula Salgado

Microbes in Health and Disease @mhd-newcastle.bsky.social · 15d

Dr Chien-Yi Chang's lab studies how Gram-negative bacteria sense and respond to different environments using molecular and bioimaging approaches.

👉 @davychang.bsky.social

chienyichang.wixsite.com/changlab

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Reposted by Prof Paula Salgado

Microbes in Health and Disease @mhd-newcastle.bsky.social · 15d

Dr Alistair Brown’s group is interested in mycobacterial biology, focusing on antimicrobial drug discovery and elucidation of drug mechanisms of action. They aim to understand how existing and novel compounds affect mycobacterial growth, survival, and persistence.

@mycobacterium-ncl.bsky.social

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Reposted by Prof Paula Salgado

Microbes in Health and Disease @mhd-newcastle.bsky.social · 15d

The Connolly group focuses on pathogenic Escherichia coli. They study how pathogen gene expression is regulated in response host-cues and determine how these expression changes lead to infection-relevant phenotypes.

Follow @ruamicro.bsky.social for more

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Reposted by Prof Paula Salgado

Microbes in Health and Disease @mhd-newcastle.bsky.social · 15d

The @henrikstrahl.bsky.social group focuses on bacterial cell envelopes and envelope-targeting antibiotics.
Using cell biology, high-end fluorescence microscopy, genetics, and biochemistry, they study the function, biosynthesis and organisation of bacterial cell membranes.

strahllab.weebly.com

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Reposted by Prof Paula Salgado

Microbes in Health and Disease @mhd-newcastle.bsky.social · 15d

Next up,

Dr Kate Beckham @kshbeckham.bsky.social

The Beckham lab is interested mycobacterial membrane transport processes. They focusing on understanding the steps occurring at the mycobacterial outer membrane.

www.ncl.ac.uk/cbcb/staff/p...

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Reposted by Prof Paula Salgado

Microbes in Health and Disease @mhd-newcastle.bsky.social · 15d

The @stewartlab.bsky.social use systems biology and cutting-edge human intestinal organoid models to understand diet-microbe-host interaction across the life course, with the ambition to discover novel therapies to improve gut health.

www.ncl.ac.uk/medical-scie...

www.neonatalresearch.net

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Reposted by Prof Paula Salgado

Microbes in Health and Disease @mhd-newcastle.bsky.social · 15d

Day 2 of MHD introductions 😃

Dr Lis Lowe @lislowe.bsky.social

The Lowe lab is focussed on microbial glycobiology. They work on bacterial Cazymes from commensals and pathogens, and are particularly interested in enzymes that target microbial glycans such as the cell walls of Mycobacteria.

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Reposted by Prof Paula Salgado

Microbes in Health and Disease @mhd-newcastle.bsky.social · 16d

Last introduction for the today..

Dr Kesha Josts @kjosts.bsky.social

The Josts lab are working on the mechanisms of iron transport in bacterial pathogens, with a focus on Pseudomonas aeruginosa.

www.ncl.ac.uk/cbcb/staff/p...

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Reposted by Prof Paula Salgado

Microbes in Health and Disease @mhd-newcastle.bsky.social · 16d

Next introducing Dr Alessandra Dantas.

The Dantas group is interested in stress responses, antifungal resistance and in understanding the molecular mechanisms driving fungal adaptation to environmental stressors.

@alesdantas.bsky.social

www.ncl.ac.uk/dental/about...

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Reposted by Prof Paula Salgado

Microbes in Health and Disease @mhd-newcastle.bsky.social · 16d

@jmarlesw.bsky.social is a structural biochemist. His group are interested in how bacteria sense and respond to their environment. Jon is Academic Lead for our Electron Microscopy Facility and is excited for our new Tundra microscope to be up and running.

www.marles-wright-lab.org

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Reposted by Prof Paula Salgado

Microbes in Health and Disease @mhd-newcastle.bsky.social · 16d

Next up, @nickj-dent-res.bsky.social
His group is interested in all aspects of oral biofilms and how they contribute to oral health and disease. They look at adhesion and colonisation of surfaces, intermicrobial interactions and the role of the biofilm matrix.

blogs.ncl.ac.uk/nickjakubovi...

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Reposted by Prof Paula Salgado

Microbes in Health and Disease @mhd-newcastle.bsky.social · 16d

The Palmer group are interested in the mechanisms bacteria use to compete with one another during colonisation. Her group are focused on the type vii secretion system and the toxins it exports.
Follow @proftracypalmer.bsky.social for more insights.
www.ncl.ac.uk/medical-scie...

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Reposted by Prof Paula Salgado

Microbes in Health and Disease @mhd-newcastle.bsky.social · 16d

Now we are on Bluesky, over the next couple of days we would like to introduce some of the MHD groups on Bluesky who you can follow for more research updates. Or check out our handy MHD starter pack 😀
go.bsky.app/SoVnvW3

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Reposted by Prof Paula Salgado

Sebastian Schmidt @tsbschm.bsky.social · 15d

Fecal filtrate is less effective than donor stool (FMT) for the treatment of C. difficile recurrence. Now shown in a multicentre trial, out today in @lancetgastrohep.bsky.social .

Congratulations to Dina Kao @ualberta.bsky.social & team!

Gift link:

authors.elsevier.com/c/1lphg8nByr...

authors.elsevier.com

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Reposted by Prof Paula Salgado

Microbes in Health and Disease @mhd-newcastle.bsky.social · 16d

The Quinn group are interested in stress-sensing and signalling mechanisms in human pathogenic fungi and their importance in virulence. They are also interested anti-fungal mechanisms mediated by the bacterial type-vi secretion system.
👉 @nclfungalgroup.bsky.social
www.ncl.ac.uk/medical-scie...

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Reposted by Prof Paula Salgado

Wiep Klaas Smits (ExpBac/CMAT) @smitslab.bsky.social · 19d

"...clinicians should be aware that CDI can occur in (premature) neonates by transfer of C. difficile at labor of a symptomatic mother" journals.lww.com/pidj/fulltex...

Maternal Transmission of Symptomatic Clostridioides... : The Pediatric Infectious Disease Journal

a complicated course in a 48-year-old mother who had prior hospitalization and antibiotic treatment. She gave birth to a triplet at a gestational age of 31 weeks and transmitted toxin-producing C. dif...

journals.lww.com

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Prof Paula Salgado @pssalgado.bsky.social · 21d

Had a great time visiting @johann-i2bc.bsky.social and Olga Soutourina's labs over the last few weeks, ending with a seminar followed by very interesting discussions with colleagues at I2BC. Going back with many ideas and can't wait to return in January to continue our collaboration!

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Prof Paula Salgado @pssalgado.bsky.social · Sep 4

A fabulous end to a fantastic #clostpath! Merci Paris! Congratulations @johann-i2bc.bsky.social Thomas Candela, Claire Morvan and Severine Pechine on a great job!

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