Raunak Basu
@raunakbasu.bsky.social
77 followers 210 following 9 posts
Assistant Professor of Neuroscience at The Edmond and Lily Safra Center for Brain Sciences
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raunakbasu.bsky.social
This project has been in the making for over half a decade and has been an active collaboration with the amazing Hiroshi Ito. Also, a big shout-out to my co-authors, Marjan Mozaffarilegha, Ipek Bölükbaşı, and Cansu Üstüner - without whom this work wouldn't have been possible.
raunakbasu.bsky.social
And finally, the formation of this OFC spatial map doesn't require the hippocampus or the medial entorhinal cortex, making it an independent spatial mapping system in the brain.
raunakbasu.bsky.social
The most remarkable feature of this map is that it remains largely stable when the spatial context is changed (such as changing the experimental room or the shape of the arena), rendering it a schematic map of space.
raunakbasu.bsky.social
Ever wonder if there are spatial maps in the brain outside the hippocampal-entorhinal regions? In this preprint, we describe a novel spatial map in the orbitofrontal cortex (OFC) that preserves the topological arrangements and distance between locations. However, ...

www.biorxiv.org/cgi/content/...
The orbitofrontal cortex forms a context-generalized spatial schema that preserves topology and distance
Flexible and efficient navigation requires the brain to construct maps that are both topological, preserving the relationships between locations, and schematic, enabling generalization across environm...
www.biorxiv.org
Reposted by Raunak Basu
carlosbrody.bsky.social
What happens in your brain when you make up your mind?

Postdoc (soon faculty at U. of Utah) @thomas-zhihao-luo.bsky.social and ex-grad student (now Shanahan Fellow at Allen Institute) @timkimd.bsky.social have some answers in this new paper out in Nature!

www.nature.com/articles/s41...

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Reposted by Raunak Basu
mace-lab.bsky.social
Thrilled to share that our work is now published in Science! ✨

We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭

www.science.org/doi/10.1126/...

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Reposted by Raunak Basu
carlosbrody.bsky.social
Complementary approach: simultaneous recordings allow analyses to see who leads and who lags. Among other results stemming from simultaneous recordings, in this preprint we show that during decision-making, frontal cortices and striatum lead, other regions lag.

doi.org/10.1101/2024...
Brain-wide coordination of decision formation and commitment
Neural correlates of a subject’s upcoming choice in decision making tasks are remarkably widespread throughout the brain, but how these brain-wide signals are coordinated remains unknown. Do brain reg...
doi.org
Reposted by Raunak Basu
hunterschone.bsky.social
Now out in @natneuro.nature.com

What happens to the brain’s body map when a body-part is removed?

Scanning patients before and up to 5 yrs after arm amputation, we discovered the brain’s body map is strikingly preserved despite amputation

www.nature.com/articles/s41593-025-02037-7

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Reposted by Raunak Basu
hunglo.bsky.social
I'm more than psyched to share that my PhD paper is now out in Neuron! It's also my first paper as both first author and corresponding author, which means even more to me!

Thank my partner Chi-Chieh for her contribution to the most adorable ever graphic abstract 🥰
Reposted by Raunak Basu
profsimonfisher.bsky.social
"Using multi-unit recording we found that inner speech is robustly represented in motor cortex, & decoded imagined sentences in real time. We demonstrate strategies to prevent brain-computer interfaces from unintentionally decoding private inner speech." Fascinating new @cp-cell.bsky.social paper:👇🧪
Inner speech in motor cortex and implications for speech neuroprostheses
Inner speech is robustly represented in the motor cortex and can be decoded in real time to restore communication to people with paralysis. Unintentional decoding of private inner speech can be preven...
www.cell.com
Reposted by Raunak Basu
Reposted by Raunak Basu
jrclimer.bsky.social
I’m excited to share my final co-first author paper from my postdoc in Dan Dombeck's lab!

We explored how behavior, senses, and neurons influence how much information in the brain changes over time.

www.nature.com/articles/s41...

#science #research #neuroscience #hippocampus #placecells
Hippocampal representations drift in stable multisensory environments - Nature
Tracking of individual place cells in mouse CA1 shows that representational drift is not influenced by changes in environment or behaviour, and is lower for more excitable place cells.
www.nature.com
raunakbasu.bsky.social
Congrats Katja!! looks amazing