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Rong @rongl.bsky.social · 11d

The brief digital edition of our @natbiotech.nature.com September issue is live now! Check it out here: mp.weixin.qq.com/s/vDXak-Ph4k...

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Nature Biotechnology @natbiotech.nature.com · 21d

On our latest podcast, Barbara Cheifet talks with Zhenan Bao and John Rogers about the latest in electronic wearables and how they will complement and advance global health — from health monitoring in neonates to smart bandages for wounds shows.acast.com/forum/episod...

Wearables Roundtable: Bao and Rogers | Forum

shows.acast.com

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Nature Biotechnology @natbiotech.nature.com · Aug 22

Stereo-cell is a DNA nanoball array-based method that enables scalable, spatially resolved single-cell sequencing across diverse cell types and sizes with multimodal integration capabilities. #NBThighlight www.science.org/doi/10.1126/...

Stereo-cell: Spatial enhanced-resolution single-cell sequencing with high-density DNA nanoball-patterned arrays

Single-cell sequencing technologies have advanced our understanding of cellular heterogeneity and biological complexity. However, existing methods face limitations in throughput, capture uniformity, c...

www.science.org

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Rong @rongl.bsky.social · Aug 14

The brief digital edition of our @natbiotech.nature.com August issue is live now! Check it out here: mp.weixin.qq.com/s/ZIDiPktIya...

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Rong @rongl.bsky.social · Jun 22

The brief digital edition of our June issue is live now! Check it out here: mp.weixin.qq.com/s/S9nAe_uF0Z...

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Nature Biotechnology @natbiotech.nature.com · Jun 20

CD8-targeted lipid nanoparticles carrying anti-CD19 CAR mRNA were developed to generate CAR-T cells directly in vivo, demonstrating effective B cell depletion for potential treatment of B cell malignancies and autoimmune diseases. www.science.org/doi/10.1126/... #NBThighlight

In vivo CAR T cell generation to treat cancer and autoimmune disease

Chimeric antigen receptor (CAR) T cell therapies have transformed treatment of B cell malignancies. However, their broader application is limited by complex manufacturing processes and the necessity f...

www.science.org

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Rong @rongl.bsky.social · May 22

The brief digital edition of our May issue is live now! Check it out here: mp.weixin.qq.com/s/Ph75nRcl02...

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Nature Biotechnology @natbiotech.nature.com · May 16

A gene-editing treatment used on a 9½-month-old boy with a rare condition has the potential to help people with thousands of other uncommon genetic diseases #NBTNewsBeat www.nytimes.com/2025/05/15/h...

Baby Is Healed With World’s First Personalized Gene-Editing Treatment

www.nytimes.com

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Nature Biotechnology @natbiotech.nature.com · May 1

This developer of cancer immunotherapies discusses her early fascination with cellular behavior, perseverance and deep desire to directly impact patient care go.nature.com/3RSlwqL
rdcu.be/ej8IO

Five questions with Jie Sun - Nature Biotechnology

This developer of cancer immunotherapies discusses her early fascination with cellular behavior, perseverance and deep desire to directly impact patient care.

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Nature Biotechnology @natbiotech.nature.com · Apr 24

Cancer vaccines: the experts speak www.nature.com/articles/s41...

Cancer vaccines: the experts speak - Nature Biotechnology

The development of therapeutic cancer vaccines has long been a promising yet challenging field of research. While early efforts were impeded by limited efficacy and immune escape, recent advances in i...

www.nature.com

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Nature Biotechnology @natbiotech.nature.com · Apr 24

Synergizing advances in artificial intelligence with mathematical modeling will improve our ability to computationally predict immunotherapy outcomes go.nature.com/4jfqM3Y
rdcu.be/eh1qR

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Nature Biotechnology @natbiotech.nature.com · Apr 25

Cell therapies are transforming our ability to treat cancer but are out of reach for many patients. We asked experts to share their insights into the challenges and strategies to make these therapies more broadly accessible go.nature.com/3YCJn1o
rdcu.be/eiaZ4

Making cell therapy accessible: challenges and opportunities - Nature Biotechnology

Despite major advances in bringing cancer cell therapies to the clinic, their widespread accessibility remains a substantial challenge. High manufacturing costs, lack of funding and varying regulatory...

go.nature.com

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Nature Biotechnology @natbiotech.nature.com · Apr 25

The identification of novel targets together with technological advances is transforming our ability to effectively modulate the tumor microenvironment go.nature.com/42Bo9lT
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Turn cold tumors hot by reprogramming the tumor microenvironment - Nature Biotechnology

The identification of novel targets together with technological advances is transforming our ability to effectively modulate the tumor microenvironment.

go.nature.com

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Rong @rongl.bsky.social · Apr 18

The brief digital edition of our 2025 Cancer Immunotherapy Focus Issue is live as well! Check it out here: mp.weixin.qq.com/s/i5t1sfgpL-...

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Iris @irismarchal.bsky.social · Apr 16

Cell therapies are transforming our ability to treat cancer but are out of reach for many patients. @natbiotech.nature.com asked experts to share their insights into pressing challenges and promising strategies to make these therapies more broadly accessible www.nature.com/articles/s41...

Making cell therapy accessible: challenges and opportunities - Nature Biotechnology

Despite major advances in bringing cancer cell therapies to the clinic, their widespread accessibility remains a substantial challenge. High manufacturing costs, lack of funding and varying regulatory...

www.nature.com

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Iris @irismarchal.bsky.social · Apr 15

Innate immune cells are promising candidates for cancer immunotherapy and various engineering strategies can be employed to set them up for success. Read about is in this Review in @natbiotech.nature.com and don't forget to check out our full Focus Issue! www.nature.com/articles/s41...

Engineering innate immune cells for cancer immunotherapy - Nature Biotechnology

The unique attributes of innate immune cells position them as attractive candidates for cancer immunotherapy, with engineering strategies to enhance their antitumor potential, offering notable therape...

www.nature.com

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Rong @rongl.bsky.social · Apr 15

This month, we've focused on recent developments as well as challenges in cancer immunotherapy, including cancer vaccines, immune checkpoint inhibitors, and CAR-engineered cells. Please read more👇

Nature Biotechnology @natbiotech.nature.com · Apr 14

Spotlight on cancer immunotherapies go.nature.com/3XUTPkM

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Rong @rongl.bsky.social · Apr 15

Our 2025 Focus issue on Cancer Immunotherapy is live now! More details below

Nature Biotechnology @natbiotech.nature.com · Apr 14

The April issue is live, with a focus on cancer immunotherapy nature.com/nbt/volumes/...

On the cover, recent clinical trials and patient reports have found promising outcomes of locoregional administration of CAR T cells across different solid tumors go.nature.com/3Z4eBiQ

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Susan Jones @jonesysoo.bsky.social · Apr 4

⭐ I'm hiring a new Chief editor for Nature Biomedical engineering, in New York, Beijing or Shanghai.

Please apply here: springernature.wd3.myworkdayjobs.com/SpringerNatu...

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Nature Biotechnology @natbiotech.nature.com · Apr 4

Sonogenetic EchoBack-CAR T cells incorporate an ultrasensitive heat-shock promoter and synthetic positive feedback loop, enabling focused-ultrasound-controlled long-lasting CAR expression and enhanced anti-tumor efficacy. www.cell.com/cell/fulltex... #NBThighlight

Engineering sonogenetic EchoBack-CAR T cells

Sonogenetic EchoBack-CAR T cells were designed with an ultrasensitive heat-shock promoter screened from a library and a synthetic positive feedback loop that reprograms tumor engagement into CAR T cel...

www.cell.com

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Nature Biotechnology @natbiotech.nature.com · Apr 2

Writing is the most essential activity of a scientist because without writing there is no thinking and no real opportunity for exchange in the marketplace of ideas go.nature.com/4iXlwRQ
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An open letter to graduate students and other procrastinators: it’s time to write - Nature Biotechnology

Nature Biotechnology - An open letter to graduate students and other procrastinators: it’s time to write

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Nature Biotechnology @natbiotech.nature.com · Apr 1

2H24 biotech job picture go.nature.com/42hUCgY

2H24 biotech job picture - Nature Biotechnology

A semiannual snapshot of job expansions, reductions and availability in the biotech and pharma sectors.

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Nature Biotechnology @natbiotech.nature.com · Apr 1

The lasso peptide lariocidin functions as a broad-spectrum antibiotic by binding to a unique site on the bacterial ribosome, disrupting protein synthesis without affecting human cells, and demonstrating low potential for resistance development. www.nature.com/articles/s41... #NBThighlight

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Rong @rongl.bsky.social · Mar 30

The brief digital edition of our March issue is live as well! Check it out here mp.weixin.qq.com/s/5MDvA1JHC0...

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Rong @rongl.bsky.social · Feb 10

New online in @naturebiotech.bsky.social: Lipid nanoparticles carrying plasmid DNA and an inflammation inhibitor enable longer transgene expression than mRNA nanoparticles-by Manthan N. Patel, Jacob S. Brenner et al.

Nature Biotechnology @natbiotech.nature.com · Feb 5

Safer non-viral DNA delivery using lipid nanoparticles loaded with endogenous anti-inflammatory lipids - @pennmedicine.bsky.social go.nature.com/3EkClak

Safer non-viral DNA delivery using lipid nanoparticles loaded with endogenous anti-inflammatory lipids - Nature Biotechnology

Lipid nanoparticles carrying plasmid DNA and an inflammation inhibitor enable longer transgene expression than mRNA nanoparticles.

go.nature.com

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