Rituraj Marwaha
rrmarwaha.bsky.social
Rituraj Marwaha
@rrmarwaha.bsky.social
IndiaAlliance ECF at TIFRH/ Guest Researcher at MPI-MR/ Interested in Organelle Mechanobiology/Doodling in my free time/ Alum-IISERMohali
Check out this stellar work by Bohra and Mazumdar @tifrhyderabad.bsky.social 🙌 👏
Bohra and Mazumder @tifrhyderabad.bsky.social show that HP1 protein dynamics at #heterochromatin damage sites differentially regulate recruitment of DSB repair factors. Disruption of phosphorylation S11–S14 residues of HP1α impairs homologous recombination. rupress.org/jcb/article/...

#Chromatin
January 8, 2026 at 4:13 AM
Reposted by Rituraj Marwaha
Nucleolar reorganization on stress depends on physicochemical changes due to nascent rRNA synthesis https://www.biorxiv.org/content/10.64898/2026.01.03.697456v1
January 3, 2026 at 2:30 PM
Reposted by Rituraj Marwaha
Glad to share our latest work that came out recently. We dive into the mechanisms of how Transcription Factors (TFs) like the nuclear receptor, ERα navigate the genome to find their targets.
December 25, 2025 at 2:44 AM
Thank you, DBT/WT India Alliance, for highlighting our work in the #IntracellularCommunication series. Truly grateful for the incredible support that has enabled us to explore lysosomal mechanosensing and collective cell migration. 🔬✨

Do check out the article.
www.linkedin.com/posts/indiaa...
Dr. Rituraj Marwaha on lysosomes and cell migration | DBT/WT India Alliance posted on the topic | LinkedIn
This week in our #IntracellularCommunication series, we feature Dr. Rituraj Marwaha! A DBT/Wellcome Trust India Alliance Early Career Fellow at the Tata Institute of Fundamental Research (TIFR) Hyder...
www.linkedin.com
November 16, 2025 at 6:33 AM
Reposted by Rituraj Marwaha
Next, Tamal Das @tifr.res.in revealed the influence of lysosomes in leader cell formation and the ER in supporting lamellipodial crawling and purse-string contraction, identifying them as key integrators of mechanochemical cues to drive collective cell migration. #MBIMPG2025
September 12, 2025 at 4:29 AM
Reposted by Rituraj Marwaha
💫NEW: Das, @fabianspill.bsky.social & co combine intracellular cartography and biophysical modelling to reveal how edge curvature governs endoplasmic reticulum (ER) morphology, showing that curvature-dependent ER reorganization directs distinct modes of epithelial cell migration.
bit.ly/3HFAQ8S
Edge curvature drives endoplasmic reticulum reorganization and dictates epithelial migration mode - Nature Cell Biology
Rawal et al. combine intracellular cartography and biophysical modelling to reveal how edge curvature governs endoplasmic reticulum (ER) morphology, showing that curvature-dependent ER reorganization ...
bit.ly
August 25, 2025 at 2:40 PM
Reposted by Rituraj Marwaha
Fresh off the press: Simran Rawal (Graduate student, Tamal Das's lab, TIFR Hyd) & colleagues find out how organelles inside epithelial cells (lining a wound) reorganise themselves & opt for specific known migratory modes in response to different curvatures of wounds.

www.nature.com/articles/s41...
Edge curvature drives endoplasmic reticulum reorganization and dictates epithelial migration mode - Nature Cell Biology
Rawal et al. combine intracellular cartography and biophysical modelling to reveal how edge curvature governs endoplasmic reticulum (ER) morphology, showing that curvature-dependent ER reorganization ...
www.nature.com
August 18, 2025 at 2:21 PM