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Sam Daly @samofmidworld.bsky.social · Jun 10

Excited to share some recent work tracking the 3D movement of individual molecules inside the organelles of living cells (💡+ 🦠 + ⚽️💨) with the best team @joechambers.bsky.social
@jamesdmanton.bsky.social
@jsbeckwith.bsky.social @dgershlick.bsky.social @stevethechemist.bsky.social

bioRxiv Biophysics @biorxiv-biophys.bsky.social · Jun 10

Volumetric single-molecule tracking inside subcellular structures https://www.biorxiv.org/content/10.1101/2025.06.09.658280v1

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Reposted by Sam Daly

Cambridge Microscopy Meeting @cmicrosocpymeeting.bsky.social · Apr 8

Big big thanks to all CMM participants & sponsors #CMM2025

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Sam Daly @samofmidworld.bsky.social · Apr 8

A short break while I present and chair a session… and we’re back! Now with an open table discussion on: MICROSCOPY! Chaired by @jsbeckwith.bsky.social, with great insights from @jamesdmanton.bsky.social and @stevethechemist.bsky.social ! #CMM2025

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Sam Daly @samofmidworld.bsky.social · Apr 8

Thank you!

Sam Daly @samofmidworld.bsky.social · Apr 8

Next up we have Bin Fu discussing analysis methods for 3D imaging and then Yuetong Jia on their autofocus method for fluorescence microscopy! #CMM2025

Reposted by Sam Daly

Cambridge Microscopy Meeting @cmicrosocpymeeting.bsky.social · Apr 7

CMM 2025 day 1

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Sam Daly @samofmidworld.bsky.social · Apr 8

Day 2 of #CMM2025! We're kicking off the first session with our third invited speaker Prof Tuomas Knowles presenting on "Probing protein self-assembly and phase transitions using microfluidics". @cmicrosocpymeeting.bsky.social

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Sam Daly @samofmidworld.bsky.social · Apr 7

And it’s a wrap for Day 1 of @cmicrosocpymeeting.bsky.social! Loads of fantastic talks, looking forward to Day 2! But for now: PUB! #CMM2025

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Sam Daly @samofmidworld.bsky.social · Apr 7

And our second keynote/final talk of the day, Siân Culley (@superresolusian.bsky.social) from KCL! Talking here about "The Good, The Bad and The Ugly in Fluorescence Microscopy" #CMM2025

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Sam Daly @samofmidworld.bsky.social · Apr 7

Next up, "Resolving Parkinson's Disease Pathology with Spatial Proteomics" from Marc Oeller. Literally cutting and sticking on a cellular level! #CMM2025

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Sam Daly @samofmidworld.bsky.social · Apr 7

We're now well into the second session of the first day, looking at further method development! We're listening to James Simon who is discussing the use of conductance microscopy in battery research, and Stefan Oswald on tracking battery ions with microscopy! #CMM2025

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Sam Daly @samofmidworld.bsky.social · Apr 7

Wooo!

a man in a tie is making a funny face with his hands in the air and the words `` so excited ! ''

ALT: a man in a tie is making a funny face with his hands in the air and the words `` so excited ! ''

media.tenor.com

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Reposted by Sam Daly

Amir Rahmani @astormic.bsky.social · Apr 7

A room full of microscopy enthusiasts, Cambridge Microscopy Meeting 2025. #CMM2025

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Sam Daly @samofmidworld.bsky.social · Apr 7

On to Session 1 now! "Method Development (Advanced illumination)", kicking off with Rebecca McClelland on accessible SIM, then Jacob Lamb on Oblique Plane Microscopy! #CMM2025

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Sam Daly @samofmidworld.bsky.social · Apr 7

Let's get the hashtag #CMM2025 for CMM2025 (@cmicrosocpymeeting.bsky.social) to get the discussion rolling!

The lecture theatre is filling up with people ready for CMM2025!

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Sam Daly @samofmidworld.bsky.social · Apr 7

And we’re off! Starting with Steven Lee’s opening remarks before handing over the Dr Lisa-Maria Needham to talk about label free detection of biomolecules!

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Sam Daly @samofmidworld.bsky.social · Apr 7

We’re busy setting up for Cambridge Microcopy Meeting 2025 this week! Looking forward to exciting talks, but first setting up space for sponsor exhibits! #cmm2025 @cmicrosocpymeeting.bsky.social @jsbeckwith.bsky.social @chemlibcam.bsky.social

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Reposted by Sam Daly

Natural History Museum, London @nhm-london.bsky.social · Mar 18

We’re thrilled to announce our exhibition, Space: Could Life Exist Beyond Earth?, opening 16 May 2025. 🚀

Rooted in the latest cutting-edge scientific research from the Museum, the exhibition will uncover evidence that life could exist beyond our planet.

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Reposted by Sam Daly

Zach Marin @zacsimile.bsky.social · Mar 10

By putting a donut between our faces and each article we read, we were able to extract more information than ever before about MINFLUX. You can read the new review article from @maxperutzlabs.bsky.social by Lukas Scheiderer, myself, and @jonasries.bsky.social at www.nature.com/articles/s41...

MINFLUX achieves molecular resolution with minimal photons - Nature Photonics

The authors review MINFLUX super-resolution microscopy, outlining its advantages and limitations, recent progress, and an outlook for future developments.

www.nature.com

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Sam Daly @samofmidworld.bsky.social · Mar 7

Excited to see that my first, first author paper out of my PhD was selected among the Top 25 Physics Research papers of 2024 by Nature Communications! @naturecomms.bsky.social www.nature.com/articles/s41...

High-density volumetric super-resolution microscopy - Nature Communications

Current approaches for volumetric super-resolution microscopy can yield large and complex PSF spatial footprints. Here, the authors show a super-resolution microscopy approach using a hexagonal microl...

www.nature.com

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Sam Daly @samofmidworld.bsky.social · Mar 4

If you're interested in advanced 3D super-resolution microscopy then there is an exciting new job opportunity in TheLeeLab here in Cambridge.

Happy to answer any questions!

🔬🧪🦠

www.jobs.cam.ac.uk/job/50547/

Postdoctoral Research Associate in Single-Molecule Imaging and Super-Resolution Microscopy (Fixed Term) - Job Opportunities - University of Cambridge

Postdoctoral Research Associate in Single-Molecule Imaging and Super-Resolution Microscopy (Fixed Term) in the Yusuf Hamied Department of Chemistry at the University of Cambridge.

www.jobs.cam.ac.uk

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Sam Daly @samofmidworld.bsky.social · Feb 8

“I make a lot less than I made in the US, and I wasn’t even head of an institution in the US, right?”

That yearly salary could fund over 30 PhDs… that’s our problem.

www.theguardian.com/education/20...

Cambridge risks losing ‘unbelievable talent’ amid PhD funding cut

Warning by vice-chancellor Deborah Prentice comes as ‘Silicon Valley’ planned between Oxford and Cambridge

www.theguardian.com

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Reposted by Sam Daly

Joe Beckwith @jsbeckwith.bsky.social · Jan 29

does anyone know of good repositories for (e.g.) nice scalable vector graphics of a microscope objective? Or have a nice svg they'd be willing to part with? @hohlbeinlab.bsky.social @jamesdmanton.bsky.social @samofmidworld.bsky.social #chemsky #microscopy

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Sam Daly @samofmidworld.bsky.social · Jan 6

First panic attack of the year! Managed to make it until the 6th Jan—good going Sam!

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Sam Daly @samofmidworld.bsky.social · Dec 24

Was I there? Yes. Am I still immensely excited for 4:10? Yes!

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