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Santhi K. Ganesh, MD @santhikganesh.bsky.social · Jul 22

@pdmace2.bsky.social @jasonkovacic.bsky.social @heatherlgornik.bsky.social @n-bouatia-naji.bsky.social @markelindsay.bsky.social

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Santhi K. Ganesh, MD @santhikganesh.bsky.social · Jul 22

Honored and grateful to receive transformative support from the 𝗟𝗲𝗱𝘂𝗰𝗾 𝗙𝗼𝘂𝗻𝗱𝗮𝘁𝗶𝗼𝗻 of our research on 𝗙𝗶𝗯𝗿𝗼𝗺𝘂𝘀𝗰𝘂𝗹𝗮𝗿 𝗗𝘆𝘀𝗽𝗹𝗮𝘀𝗶𝗮. Excited to begin work with our 𝗔𝗟𝗜𝗚𝗡-𝗙𝗠𝗗 Network and proud to partner with Jason Kovacic, Stéphanie Debette, Nabila Bouatia-Naji, Manuel Mayr, and Mark Lindsay. #FMD

We are thrilled to share that Michigan Medicine has been awarded a new, international research grant for more than $8.5 million by the Leducq Foundation to advance research into fibromuscular… | Michi...

We are thrilled to share that Michigan Medicine has been awarded a new, international research grant for more than $8.5 million by the Leducq Foundation to advance research into fibromuscular dysplasi...

www.linkedin.com

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Reposted by Santhi K. Ganesh, MD

Eric Topol @erictopol.bsky.social · Mar 10

99% of new medicines developed by the pharmaceutical industry depend on NIH research jamanetwork.com/journals/jam...

Comparison of Research Spending on New Drug Approvals by the NIH vs the Pharmaceutical Industry

This cross-sectional study examines National Institutes of Health and pharmaceutical industry investments in recent drug approvals.

jamanetwork.com

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Santhi K. Ganesh, MD @santhikganesh.bsky.social · Mar 5

From Science Advances - a new collection on Advancing the Science of Women’s Health. www.science.org/toc/sciadv/c...

Contents | Science Advances 11, 10

www.science.org

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Reposted by Santhi K. Ganesh, MD

Dr Martha Gulati @drmarthagulati.bsky.social · Feb 4

Heart disease in women is far too often misdiagnosed or dismissed

A (not so) shocking 84% of female cardiologists surveyed reported treating women whose symptoms were ignored or misdiagnosed

This is disgraceful. Advocate for better awareness.
#CVprev #Cardiosky
#HeartAndSoul

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Reposted by Santhi K. Ganesh, MD

Alt NIH Bluesky 🧪 @altnih4science.bsky.social · Jan 30

This account is for sharing info with US scientists, both extramural and intramural to NIH, about attacks on science in the US.

Education is power, and we can help advocate for science and medicine together. 💪🧪

We are a team of NIH people. Please ask us questions you might have.

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Santhi K. Ganesh, MD @santhikganesh.bsky.social · Jan 28

www.sciencedirect.com/science/arti... #SCAD

Pregnancy-Associated Myocardial Infarction in Alberta: A Population-Based Study

Cardiac disease is the leading cause of maternal mortality in developed countries, and myocardial infarction (MI) is an important cause of pregnancy-a…

www.sciencedirect.com

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Santhi K. Ganesh, MD @santhikganesh.bsky.social · Jan 27

www.ahajournals.org/doi/10.1161/... #FMD

Arterial Hypertension in Women: State of the Art and Knowledge Gaps | Hypertension

Hypertension is the leading risk factor for cardiovascular disease and premature death among women globally. However, there is a fundamental lack of knowledge regarding the sex-specific pathophysiolog...

www.ahajournals.org

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Reposted by Santhi K. Ganesh, MD

Kara Gavin @karagavin.bsky.social · Jan 22

Umich faculty with NIH funding: please DM me if you’re hearing of study section disruptions in your subfield.

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Santhi K. Ganesh, MD @santhikganesh.bsky.social · Dec 12

Pretty neat - the placenta-tropic lipid nanoparticle formulation had an order of magnitude greater mRNA delivery than current standards.

Jalees Rehman @jalees.bsky.social · Dec 12

Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia

www.nature.com/articles/s41...

Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia - Nature

A platform for mRNA lipid nanoparticle delivery to the placenta to treat pre-eclampsia is shown to improve fetal and maternal health in mice and has potential clinical applications in obstetric d...

www.nature.com

Reposted by Santhi K. Ganesh, MD

Jalees Rehman @jalees.bsky.social · Dec 12

Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia

www.nature.com/articles/s41...

Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia - Nature

A platform for mRNA lipid nanoparticle delivery to the placenta to treat pre-eclampsia is shown to improve fetal and maternal health in mice and has potential clinical applications in obstetric d...

www.nature.com

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Santhi K. Ganesh, MD @santhikganesh.bsky.social · Dec 10

Agree 💯 that more work is needed to address gaps in women's health research in the recent National Academies report, including CVDs.

www.science.org/content/arti...

nap.nationalacademies.org/download/28586

A New Vision for Women's Health Research: Transformative Change at the National Institutes of Health

Read online, download a free PDF, or order a copy in print.

nap.nationalacademies.org

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Reposted by Santhi K. Ganesh, MD

Jacqueline S. Dron, PhD @jsdron.bsky.social · Dec 4

Applications are now OPEN for the 2025 Human Genetics and Genomics GRC and GRS!! 🎉 🧬

📅 GRS: July 5-6, 2025
📅 GRC: July 6-11, 2025
📍 Portland, Maine

@calliao.bsky.social and I are co-chairs for the GRS, with Shamil Sunyaev and @eimearekenny.bsky.social as the GRC chairs 👀

Links to apply below 👇

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Santhi K. Ganesh, MD @santhikganesh.bsky.social · Nov 26

Dongwon and team are terrific!

Reposted by Santhi K. Ganesh, MD

Heidi Rehm @heidirehm.bsky.social · Nov 22

I know many of you have been awaiting us launching transcript expression data in gnomAD. We were waiting for the GTEx v10 release which is now out so we are finally able to launch this. Enjoy!!

Genome Aggregation Database (gnomAD) @gnomad-project.bsky.social · Nov 22

Proportion expressed across transcripts (pext), using GTEx v10, is now available on #gnomAD v4!

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Santhi K. Ganesh, MD @santhikganesh.bsky.social · Nov 20

Age 18-40, nearly 1/3 with hypertension had a form of secondary hypertension, of which renovascular hypertension was the etiology in 18.4%

www.ahajournals.org/doi/10.1161/...

Prevalence and Risk Factors for Secondary Hypertension in Young Adults | Hypertension

BACKGROUND: The prevalence of secondary causes of hypertension in young adults is unknown, and therefore, there is no consensus about the indication of screening of secondary hypertension (2HTN) in th...

www.ahajournals.org

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Santhi K. Ganesh, MD @santhikganesh.bsky.social · Nov 20

Terrific to see your and @pdmace2.bsky.social patient support activities and all the engagement - great work!

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Reposted by Santhi K. Ganesh, MD

Heather Gornik @heatherlgornik.bsky.social · Nov 20

Outstanding presentation by @santhikganesh.bsky.social to our UH Harrington HVI and FMDSA virtual support group: What the patient should know about FMD/SCAD genetics. Able to host 250 people from around the world. I appreciate her making complex genetic concepts accessible. Pardon rough images.

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Reposted by Santhi K. Ganesh, MD

euanashley @euanashley.bsky.social · Nov 18

The era of precision therapy for inherited cardiovascular disease is here. To date, we had almost nothing to offer patients with severe inherited cardiomyopathy.

We are now on the verge of a new chapter with dozens of genetic-based therapies entering clinical trials.

www.nejm.org/doi/full/10....

Phase 1 Study of AAV9.LAMP2B Gene Therapy in Danon Disease | NEJM

Danon disease is a rare, X-linked, monogenic cardiomyopathy caused by mutations in the lysosomal-associated membrane 2 gene (LAMP2), which encodes the LAMP2 protein. In male patients, the predomina...

www.nejm.org

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Reposted by Santhi K. Ganesh, MD

Sergiu P. Pasca @sergiuppasca.bsky.social · Nov 17

Research funded by NIH generated $2.46 in economic activity for every $1 of funding in 2023 [a total of $92.9 billion]

www.fiercebiotech.com/research/rep...

Report: Every dollar of NIH research funding doubles in economic returns

Research funded by the National Institutes of Health (NIH) generated $2.46 in economic activity for every $1 of funding in 2023, a total of $92.9 billion, according to an

www.fiercebiotech.com

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Santhi K. Ganesh, MD @santhikganesh.bsky.social · Nov 18

Dr. Wenger’s charge to the next generation of researchers in women's cardiovascular health: “Investigate, educate, advocate, and legislate”

Dr. Nanette Wenger, the queen of hearts

Heart disease was once considered a man's disease. Dr. Nanette Wenger changed that. But the 93-year-old cardiologist says her work is not yet done.

www.heart.org

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Reposted by Santhi K. Ganesh, MD

AHA Science @ahascience.bsky.social · Nov 17

At #AHA24, Dr. Nanette Wenger reminds us we’re all ‘standing on the shoulders of giants’ in healthcare. As we celebrate 100 years of Scientific Sessions, we honor the pioneers who paved the way and look ahead to a new century of innovation.

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Santhi K. Ganesh, MD @santhikganesh.bsky.social · Nov 17

What a privilege to hear a talk from Dr. Bruce Beutler, Nobel Laureate, at #AHA2024 on defining innate immunity in human diseases using forward genetic approaches. Inspiring work from an incredibly accomplished physician-scientist.

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Reposted by Santhi K. Ganesh, MD

Parham Eshtehardi MD @cardioobdoc.bsky.social · Nov 16

Welcome to societies/journals joined 🦋👇 #AHA24 #CardioSky

ACC @accintouch.bsky.social
AHA Sciences @ahascience.bsky.social
AHA Journals @ahajournals.bsky.social
JAMA @jamacurrent.bsky.social
ASPC @aspcardio.bsky.social
Am J Prev Card @ajpcardio.bsky.social
J Card Fail @jcardfail.bsky.social

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Santhi K. Ganesh, MD @santhikganesh.bsky.social · Nov 15

Recently back from a lovely visit @Duke to support PRVH research and patient care, at our 3rd International PRVH Symposium hosted and led by @ColemanDM_vasc. Terrific to see all the progress for this rare disease since we first convened in 2019 in Ann Arbor, MI. #PCORI #HTN #FMD
www.prvh-pcor.org

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