Lightnews — Scholar-powered news

Sarah Ross @sarahhross.bsky.social · Aug 18

Well, this is rather wonderful! #IUIS2025

Sarah Ross @sarahhross.bsky.social · Aug 16

The human immune system evolved over millennia - and can adapt within a single lifetime. This review examines how the immune responses change over the life course. By Jessica Metcalf, Andrea Graham, Andrew Yates and Derek Cummings @science.org

buff.ly/GJpPUO7

8 37

Sarah Ross @sarahhross.bsky.social · Aug 16

Tissue immunity meets biological sex differences - context is important in the immune system. Another of my reading recommendations during a trip to @iuis-online.bsky.social Congress. From Sonia Sharma, Alicia Gibbons and Erica Ollmann Saphire in @science.org

buff.ly/XPN0Tpb

8 23

Sarah Ross @sarahhross.bsky.social · Aug 16

If you are looking for a great read during your journey to @iuis-online.bsky.social Congress, take a peek at this review from from Matthias Nahrendorf, Florent Ginhoux and @filswirski.bsky.social in @science.org that explores the role of immune cells beyond host defence.

buff.ly/S5RkqTf

3 10

Sarah Ross @sarahhross.bsky.social · Aug 16

Anyone traveling to @iuis-online.bsky.social Congress and looking for something to read? Don't miss the reviews from our @science.org Evolving Immunity Special Issue!
Here, Kassiotis and Stoye consider endogenous retroviruses and antiviral defences.

buff.ly/IU4nbSE

2

Sarah Ross @sarahhross.bsky.social · Aug 16

Such a beautiful and intricate image! I was fascinated by the creative process for the cover, and loved getting a behind-the-scenes look at the work of artist Rioka Hayama and the Science Visuals team. Have you guessed all the features yet?

Science Magazine @science.org · Aug 12

Can you can identify these 10 components featured on our Evolving Immunity special issue cover? 🔎

Drop your guesses in the comments. We’ll reveal the answers next week, so stay tuned!

Discover more about the special issue here: https://scim.ag/3JdpWYj

A black and white illustration depicting the changes in the immune system throughout an individual’s life span, from infancy to childhood, adulthood, and older age. There are blank labels 1–10 throughout the illustration.

An illustration depicting the changes in the immune system throughout an individual’s life span, from infancy to childhood, adulthood, and older age.

6 20

Sarah Ross @sarahhross.bsky.social · Aug 16

Not long to go - I'm looking forward to some fantastic immunology!

Seth Thomas Scanlon @immunoeditor.bsky.social · Aug 15

Heads up: @science.org 's immunology editor @sarahhross.bsky.social and I will both be attending the @iuis-online.bsky.social 19th International Congress next week in the ever enchanting city of #Vienna! We hope to see many of you there!

Home - IUIS 2025

IUIS 2025 ACCREDITED WITH 26 CME CREDITSThe 19th International Congress of Immunology (IUIS 2025), Vienna, Austria 17/08/2025 – 22/08/2025, has been accredited by the European Accreditation Council fo...

iuis2025.org

5

Sarah Ross @sarahhross.bsky.social · Aug 7

This week @science.org examines the wonders of the immune system! From molecular defences that co-evolved with pathogens to specialised cells that are intricately linked with physiology, the immune system is attuned to biological sex and different stages of life.

Science Magazine @science.org · Aug 7

A new special issue of Science explores the immune system at the molecular and cellular level and how it has evolved to govern multiple facets of human health.

Learn more: scim.ag/3IYhnk7

This illustration depicts the changes in the immune system throughout an individual’s life span, from infancy to childhood, adulthood, and older age.

11 43

Sarah Ross @sarahhross.bsky.social · Apr 11

#Immunology out now @science.org

After initial priming in the lymph nodes, mouse CD8 T cells undergo a second phase of stable interactions with dendritic cells that can preferentially stimulate those with a high-affinity for antigen.

buff.ly/49bKcTG

By Jobin, Seetharama, Rüttger et al.

11 39

Sarah Ross @sarahhross.bsky.social · Apr 4

#Immunology out now @science.org

Regulatory T cells inhibit pain sensing in female, but not male, mice.

buff.ly/SKtHnfK

By Élora Midavaine, Sakeen Kashem et al.

6 48

Sarah Ross @sarahhross.bsky.social · Mar 14

ICYMI by First release - now in print @science.org

Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection.

buff.ly/3DjNQ1e

By @cicacanesso.bsky.social @danmucida.bsky.social @victora.bsky.social et al

2 17 58

Sarah Ross @sarahhross.bsky.social · Feb 27

#Immunology by First Release @science.org

In mice, during immune responses accompanied by elevated self-antigens, autoreactive CD4 T cells must be restrained by regulatory CD4 T cells with the same antigen specificity to prevent autoimmunity.

buff.ly/3EXaXQa

3 23

Sarah Ross @sarahhross.bsky.social · Feb 20

#Immunology out now @science.org

Machine learning, using the sequences of an individual's B and T cell receptors, has the potential to diagnose immune-related diseases.

https://buff.ly/3QvxSVf

By Maxim Zaslavsky, Erin Craig, @anshulkundaje.bsky.social , @scottboydlab.bsky.social et al.

2 21 85

Sarah Ross @sarahhross.bsky.social · Feb 13

#Immunology out now @science.org

In mice, the transcription factor KLF2 keeps activated CD8 T cells on track to differentiate into functional effector T cells.

https://buff.ly/4hBmL8W

By Eric Fagerberg, Nikhil Joshi @nikjoshilabyale.bsky.social et al

4 40

Sarah Ross @sarahhross.bsky.social · Feb 7

ICYMI by First Release - now officially in print @science.org

Specific combinations of nutrients and metabolic enzymes determine T cell differentiation via loci-specific histone acetylations.

https://buff.ly/4gvqKTz

From Shixin Ma, Sue Kaech @tcellogic.bsky.social et al.

#immunometabolism

16 50

Sarah Ross @sarahhross.bsky.social · Feb 5

Not long to go now! Don’t miss out on applying for the NOSTER & @science.org Microbiome Prize!

Enter: buff.ly/4gS29ZH
More details: ⤵️

Sarah Ross @sarahhross.bsky.social · Jan 14

If you're doing innovative research about #microbiota and received an MD &/or PhD in last 10 years don’t miss out on applying for the NOSTER & @science.org Microbiome Prize!

Grand Prize: $25K & your essay published in Science Magazine

Deadline: Feb 14th
Enter: https://buff.ly/4gS29ZH

Sarah Ross @sarahhross.bsky.social · Jan 31

This Perspective from Aaron Ver Heul puts the work of Andrew Liu, @danhkaplan.bsky.social et al into context.

https://buff.ly/40Bp1G1

#Immunology @science.org

1 4

Sarah Ross @sarahhross.bsky.social · Jan 31

#Immunology out now @science.org

Scratching in mice promotes pain-sensing neurons to release a neuropeptide that stimulated antigen-activated mast cells to degranulate and produce inflammatory mediators.

https://buff.ly/4hDAgF2

From Andrew Liu, @danhkaplan.bsky.social et al

3 15

Sarah Ross @sarahhross.bsky.social · Jan 24

ICYMI by First Release - now officially in print @science.org

Plasma cells producing high-affinity antibodies dominate the plasma cell population through increased proliferation.

https://buff.ly/3BzpLmL

By Andrew MacLean, Michel Nussenzweig et al.

#Immunology

4 17

Sarah Ross @sarahhross.bsky.social · Jan 16

#Immunology out now @science.org

ILC2s contribute to glucose homeostasis. Neurons that innervate the gut from areas of the brain associated with glucose sensing can stimulate ILC2s in the gut to relocate to the pancreas upon fasting.

https://buff.ly/42iBst0

10 31

Sarah Ross @sarahhross.bsky.social · Jan 14

If you're doing innovative research about #microbiota and received an MD &/or PhD in last 10 years don’t miss out on applying for the NOSTER & @science.org Microbiome Prize!

Grand Prize: $25K & your essay published in Science Magazine

Deadline: Feb 14th
Enter: https://buff.ly/4gS29ZH

4 5

Sarah Ross @sarahhross.bsky.social · Dec 19

#Immunology by first release now @science.org

Plasma cells producing high-affinity antibodies dominate the plasma cell population through increased proliferation.

https://buff.ly/3BzpLmL

By Andrew MacLean, Michel Nussenzweig et al.

10 30

Sarah Ross @sarahhross.bsky.social · Dec 19

This Perspective by Sonja Best and Adam Hage puts tuning the MAVS signalosome by cellular mRNAs into context.

buff.ly/4fxVMcx

#Immunology @science.org

3 23

Sarah Ross @sarahhross.bsky.social · Dec 19

#Immunology by First release now @science.org

Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection

https://buff.ly/3DjNQ1e

By Maria Canesso, @danmucida.bsky.social , @victora.bsky.social and colleagues.

30 65

Sarah Ross @sarahhross.bsky.social · Dec 19

#Immunology out now @science.org

An unstructured region within MAVS interacts with cellular, rather than viral, RNA. This alters how MAVS interacts with other proteins and influences antiviral responses.

https://buff.ly/4grnf18

By @nandangokhale.bsky.social with @ramlabuw.bsky.social et al.

1 6 20