SHUBHAM
@shubham-das.bsky.social
Postdoctoral Fellow at @stanford.edu
New preprint:
We identify a dual regulatory role of nuclear FNBP4 in actin dynamics: the C-terminus binds actin, while the N-terminus inhibits the formin FMN1.
Thanks to @Sankar_Maiti @iiserkol, #Actin_Cytoskeleton_Dynamics_Lab
doi.org/10.64898/202...
#actin #biochemistry #nucleus #formin #fnbp4
We identify a dual regulatory role of nuclear FNBP4 in actin dynamics: the C-terminus binds actin, while the N-terminus inhibits the formin FMN1.
Thanks to @Sankar_Maiti @iiserkol, #Actin_Cytoskeleton_Dynamics_Lab
doi.org/10.64898/202...
#actin #biochemistry #nucleus #formin #fnbp4
doi.org
January 12, 2026 at 1:40 AM
New preprint:
We identify a dual regulatory role of nuclear FNBP4 in actin dynamics: the C-terminus binds actin, while the N-terminus inhibits the formin FMN1.
Thanks to @Sankar_Maiti @iiserkol, #Actin_Cytoskeleton_Dynamics_Lab
doi.org/10.64898/202...
#actin #biochemistry #nucleus #formin #fnbp4
We identify a dual regulatory role of nuclear FNBP4 in actin dynamics: the C-terminus binds actin, while the N-terminus inhibits the formin FMN1.
Thanks to @Sankar_Maiti @iiserkol, #Actin_Cytoskeleton_Dynamics_Lab
doi.org/10.64898/202...
#actin #biochemistry #nucleus #formin #fnbp4
Reposted by SHUBHAM
Meeting Alert! Santa Cruz Developmental Biology Meeting! 👇 @socdevbio.bsky.social @insdb.bsky.social @bscb-official.bsky.social @isdb.bsky.social @bsdb.bsky.social @ascbiology.bsky.social
The 2026 Santa Cruz Developmental Biology Meeting website is LIVE!!! Go see the incredible list of scientists who will be speaking at the meeting next summer! (...and check the site early next year for info on registration and abstract submission.)
scdb2026.sites.ucsc.edu
scdb2026.sites.ucsc.edu
Santa Cruz Developmental Biology Meeting
scdb2026.sites.ucsc.edu
December 19, 2025 at 8:40 PM
Meeting Alert! Santa Cruz Developmental Biology Meeting! 👇 @socdevbio.bsky.social @insdb.bsky.social @bscb-official.bsky.social @isdb.bsky.social @bsdb.bsky.social @ascbiology.bsky.social
Reposted by SHUBHAM
Perspective @jcb.org by Richard McIntosh describing the history of research on #microtubule polymerization in terms of the ideas, technologies, and observations that have emerged as countless researchers have studied the dynamics of these essential cytoskeletal polymers. rupress.org/jcb/article/...
October 15, 2025 at 4:00 PM
Perspective @jcb.org by Richard McIntosh describing the history of research on #microtubule polymerization in terms of the ideas, technologies, and observations that have emerged as countless researchers have studied the dynamics of these essential cytoskeletal polymers. rupress.org/jcb/article/...
Reposted by SHUBHAM
Call for papers: Cell Biology of the Nucleus
We invite you to submit your latest research to our special issue: Cell Biology of the Nucleus, guest edited by @abbybuch.bsky.social alongside JCS Editor Megan King @luskinglab.bsky.social.
Deadline: 3 November
journals.biologists.com/jcs/pages/nu...
We invite you to submit your latest research to our special issue: Cell Biology of the Nucleus, guest edited by @abbybuch.bsky.social alongside JCS Editor Megan King @luskinglab.bsky.social.
Deadline: 3 November
journals.biologists.com/jcs/pages/nu...
August 28, 2025 at 1:56 PM
Call for papers: Cell Biology of the Nucleus
We invite you to submit your latest research to our special issue: Cell Biology of the Nucleus, guest edited by @abbybuch.bsky.social alongside JCS Editor Megan King @luskinglab.bsky.social.
Deadline: 3 November
journals.biologists.com/jcs/pages/nu...
We invite you to submit your latest research to our special issue: Cell Biology of the Nucleus, guest edited by @abbybuch.bsky.social alongside JCS Editor Megan King @luskinglab.bsky.social.
Deadline: 3 November
journals.biologists.com/jcs/pages/nu...
🚨 New publication out in @jbiolchem!
We show how FNBP4 inhibits FMN1-mediated actin dynamics, revealing key regulatory mechanisms of non-diaphanous formin. Grateful to @Maiti_SP for his guidance and @ANRFIndia for funding!
🔗 doi.org/10.1016/j.jbc.…#ActinCytoskeletononwww.jbc.org/article/S002...xt
We show how FNBP4 inhibits FMN1-mediated actin dynamics, revealing key regulatory mechanisms of non-diaphanous formin. Grateful to @Maiti_SP for his guidance and @ANRFIndia for funding!
🔗 doi.org/10.1016/j.jbc.…#ActinCytoskeletononwww.jbc.org/article/S002...xt
Nuclear protein FNBP4: A novel inhibitor of non-diaphanous formin FMN1-mediated actin cytoskeleton dynamics
Formin1 (FMN1), a member of the non-diaphanous formin family, is essential for development
and neuronal function. Unlike diaphanous-related formins, FMN1 is not subject to canonical
autoinhibition thr...
www.jbc.org
August 6, 2025 at 8:39 PM
🚨 New publication out in @jbiolchem!
We show how FNBP4 inhibits FMN1-mediated actin dynamics, revealing key regulatory mechanisms of non-diaphanous formin. Grateful to @Maiti_SP for his guidance and @ANRFIndia for funding!
🔗 doi.org/10.1016/j.jbc.…#ActinCytoskeletononwww.jbc.org/article/S002...xt
We show how FNBP4 inhibits FMN1-mediated actin dynamics, revealing key regulatory mechanisms of non-diaphanous formin. Grateful to @Maiti_SP for his guidance and @ANRFIndia for funding!
🔗 doi.org/10.1016/j.jbc.…#ActinCytoskeletononwww.jbc.org/article/S002...xt
Reposted by SHUBHAM
Mechanistic Insights into FNBP4-Mediated Regulation of non-diaphanous Formin FMN1 in Actin Cytoskeleton Dynamics www.biorxiv.org/content/10.1...
Mechanistic Insights into FNBP4-Mediated Regulation of non-diaphanous Formin FMN1 in Actin Cytoskeleton Dynamics
Formin1 (FMN1), a member of the non-diaphanous formin family, is essential for development and neuronal function. Unlike diaphanous-related formins, FMN1 is not subject to canonical autoinhibition thr...
www.biorxiv.org
December 10, 2024 at 1:12 PM
Mechanistic Insights into FNBP4-Mediated Regulation of non-diaphanous Formin FMN1 in Actin Cytoskeleton Dynamics www.biorxiv.org/content/10.1...
August 6, 2025 at 6:28 PM