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Reposted by Dr. Sarah Signor

AAUP @aaup.org · 23h

Join the AAUP and other allied organizations across the nation on October 18 for a day of peaceful and impactful protest as we come together to make clear: America has no kings, and the power belongs to the people!

#NoKings #AAUP #AcademicFreedom #HigherEducation #DefendHigherEd #Education

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Dr. Sarah Signor @signor-molevol.bsky.social · 1d

Tonsils coming out today, but he's mostly interested in sperms whales 🤣🤣

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Dr. Sarah Signor @signor-molevol.bsky.social · 1d

This manuscript was so much fun to write! Who thought we'd find an ongoing invasion in Dmel. TEs are so cool 😎

Riccardo Pianezza @rpianezza.bsky.social · 5d

We discovered an endogenous retrovirus that's still spreading in natural D. melanogaster populations! It was horizontally transferred from D. erecta in Central Africa, so we named it "Kuruka", which means "jump" in Swahili. Read its cool story here: www.biorxiv.org/content/10.1...

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Reposted by Dr. Sarah Signor

Cedric Feschotte @cedricfeschotte.bsky.social · 16d

📣 Our department is hiring an Assistant Professor in Evolutionary Cell and Molecular Biology to join the @weillinstitute.bsky.social PLS spread the word!
academicjobsonline.org/ajo/jobs/30607

Cornell University, Molecular Biology & Genetics

Job #AJO30607, WDR-00055221 Assistant Professor, Molecular Biology & Genetics, Cornell University, Ithaca, New York, US

academicjobsonline.org

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Reposted by Dr. Sarah Signor

Rebecca R Helm @rebeccarhelm.bsky.social · 20d

“Who me? As a tripod fish, I deal with stress and fear by transforming into an eyeless abyssal predatory elder god. What about you?”

🎥 Huge thanks to @frida.yolotzin for letting me use the baby tripod fish video, and @schmidtocean for permission to share the adult video.

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Reposted by Dr. Sarah Signor

Andres Bendesky @bendeskylab.com · 18d

Tenure-track Assistant Professor in Computational Ecology and/or Evolution @columbiauniversity.bsky.social.
Deadline to apply September 30.
Reach out if you have questions.

apply.interfolio.com/172496

Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

apply.interfolio.com

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Dr. Sarah Signor @signor-molevol.bsky.social · 20d

Yaaay! Congratulations, much deserved.

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Reposted by Dr. Sarah Signor

Ned Dochtermann @neddochtermann.bsky.social · Sep 8

New preprint out from the lab, including @rroyaute.bsky.social:
www.biorxiv.org/content/10.1...

In this we test what we refer to as the "standard model" of behavioral variation.

This was inspired by recent work identifying intra-genotypic variation as a major contributor to "individuality".
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Genetic and environmental sources of behavioral individuality: a test of the standard model

Behavioral variation is typically assumed to arise from the combination and interaction of genetic and environmental variation. However, recent work with genetically identical individuals has found th...

www.biorxiv.org

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Dr. Sarah Signor @signor-molevol.bsky.social · Sep 5

Tenure seminar, done!

Anuj Ghimire @thebirdguy.bsky.social · Sep 5

Time to learn about transposons with @signor-molevol.bsky.social

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Dr. Sarah Signor @signor-molevol.bsky.social · Sep 3

From now on I'm measuring stress levels in terms of old coffee cups. Currently at level 8

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Reposted by Dr. Sarah Signor

Matt Beaumont @mbeaum.bsky.social · Aug 28

Germline defence from TEs largely relies on piRNAs. Yet, @divyaselvaraju.bsky.social and I monitored a P-element invasion in Drosophila that was stopped by an internally deleted copy, no host intervention required!
doi.org/10.1371/jour...
Many thanks to @rpianezza.bsky.social & @rokofler.bsky.social

Rapid emergence of non-autonomous elements may stop P-element invasions in the absence of a piRNA-based host defence

Author summary Transposable elements (TEs) are short, self-replicating DNA sequences found in nearly all genomes. While they can be harmful to their hosts, many organisms have evolved defence systems,...

journals.plos.org

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Dr. Sarah Signor @signor-molevol.bsky.social · Aug 25

Registering a lab server with the university IT department, call if you don't hear from me within three days 🤣

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Dr. Sarah Signor @signor-molevol.bsky.social · Aug 22

Nooooooooooo

Saccharomyces Genome Database @yeastgenome.bsky.social · Aug 22

Utterly devastating: FlyBase zapped.

www.thetransmitter.org/community/ha...

#modelOrganism

Exclusive: Harvard University lays off fly database team

The layoffs jeopardize this resource, which has served more than 4,000 labs for about three decades.

www.thetransmitter.org

Dr. Sarah Signor @signor-molevol.bsky.social · Aug 21

Heng Li and his lab are just out here propping up our entire field
doi.org/10.1101/2025...

Efficient near telomere-to-telomere assembly of Nanopore Simplex reads

Telomere-to-telomere (T2T) assembly is the ultimate goal for de novo genome assembly. Existing algorithms capable of near T2T assembly all require Oxford Nanopore Technologies (ONT) ultra-long reads w...

doi.org

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Reposted by Dr. Sarah Signor

Adam Parkhomenko @adamparkhomenko.bsky.social · Aug 12

holy shit this is a helluva ad from the Democrat running against Joni Ernst in Iowa. worth every second

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Reposted by Dr. Sarah Signor

José Cerca @naturalselection.bsky.social · Aug 19

The 2025-26 Eco-Evo job list is out. Good luck to those applying!

docs.google.com/spreadsheets...

ecoevojobs.net 2025-26

docs.google.com

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Dr. Sarah Signor @signor-molevol.bsky.social · Aug 19

The lab is going to look so cool for the fall of American democracy

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Dr. Sarah Signor @signor-molevol.bsky.social · Aug 19

The Signor lab is loving our new lab shwag, designed by the ever wonderful @nepeteaa.bsky.social

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Dr. Sarah Signor @signor-molevol.bsky.social · Aug 15

@shashankpritam.bsky.social first research paper on the effect of insertion bias on transposon fitness!! With @almoroscarpa.bsky.social and @rokofler.bsky.social link.springer.com/article/10.1...

The impact of insertion bias into piRNA clusters on the invasion of transposable elements - BMC Biology

Background In our current understanding of transposable element (TE) invasions, TEs move freely until they accidentally insert into a piRNA cluster, where they are silenced by the production of piRNA ...

link.springer.com

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Dr. Sarah Signor @signor-molevol.bsky.social · Aug 8

Anyone else cave and use osx because open source Linux wasn't broadly stable/usable enough but now osx makes it's own chips and nothing is compatible

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Dr. Sarah Signor @signor-molevol.bsky.social · Aug 3

If declining to review requires more than clicking a button I'm going to ghost the invitation I'm sorry

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Reposted by Dr. Sarah Signor

Ralf Jansen @ralfjansen.bsky.social · Aug 2

My colleagues Baptise Rafanel et al. investigated how a newly invading transposon can be silenced. They found that not only antisense insertions in piRNA clusters such as flamenco, but also insertions in the 3‘UTR of genes can drive potent silencing.

bioRxiv Genetics @biorxiv-genetic.bsky.social · Aug 1

Antisense transposon insertions into host genes trigger piRNA mediated immunity https://www.biorxiv.org/content/10.1101/2025.07.28.667215v1

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Dr. Sarah Signor @signor-molevol.bsky.social · Aug 1

I approve of this message

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