Simon Sprecher
@simon-sprecher.bsky.social
800 followers 560 following 16 posts
Professor in Neurobiology at University of Fribourg @unifr @unifrBiology bringing #neurogenetics from #Drosophila to #Cephalopods and #Cnidaria -View are my own
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simon-sprecher.bsky.social
We have open PhD positions in the lab to work in the Neuroscience of #Cephalopods #Cnidaria and #Drosophila-
please RT

www.sprecherlab.com
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www.sprecherlab.com
simon-sprecher.bsky.social
Fabulous! Congratulations Silke!!!
Reposted by Simon Sprecher
fly-eds.bsky.social
Recently completed your #PhD using #Drosophila in a European lab? Apply for the European Drosophila Society best thesis prize!
🏆🪰
Deadline: 28 Feb 2025.
Prize = €1000 & keynote presentation at the EDRC in Alicante @edrc2025.bsky.social!
Info here: europeandrosophilasociety.org/eds-best-phd...
EDS best PhD thesis prize | European Drosophila SocietyHome
europeandrosophilasociety.org
simon-sprecher.bsky.social
We definitely should- ok, we will 👍😉
simon-sprecher.bsky.social
Congratulations Dion et al!
simon-sprecher.bsky.social
Thanks Eric! Really nice that NPR picked it up…!
Reposted by Simon Sprecher
katrinvogt.bsky.social
Creamy potato chips and slimy apples - at least for humans, that doesn't seem tasty. Also the fruit fly larva is picky and prefers a certain food hardness: enjoy reading more about that in the primer I wrote for the recent paper from the @simon-sprecher.bsky.social lab.
plosbiology.org
Food’s smell, look & texture are as important as taste. @katrinvogt.bsky.social explores a @plosbiology.org study showing that fly larvae respond to food texture and integrate information from different modalities within a single neuron 🧪 Primer: plos.io/3CFhaiI Paper: plos.io/3CEv5FJ
This schematic shows how fly larvae evaluate food texture and choose soft rotten fruits over harder ripe ones, even though both contain sweet fructose. Sweet taste and soft texture information activate a single bilaterally expressing sensory neuron type in the larval head, projecting to the larval brain.
Reposted by Simon Sprecher
roliroberts.bsky.social
This is a fascinating paper that handled at @plosbiology.org (with thanks to Matthieu Louis as guest ed). The quotation that springs to mind is "Is it nice, my preciousss? Is it juicy? Is it scrumptiously crunchable?" - @simon-sprecher.bsky.social and colleagues titrate agarose to find out...
plosbiology.org
Sensing food is a complex multisensory experience. A study of food hardness preference in #FruitFly larvae by @simon-sprecher.bsky.social &co reveals that gustatory organ sensory neurons can perceive cues of both chemical & mechanical stimulation 🧪 @plosbiology.org plos.io/3CEv5FJ
Top left: Top—cartoon of larval food environment, showing a harder (fresh) fruit and a softer (ripe) fruit. Bottom—larval ingestion can be visualised by blue-dyed agarose present and visible in the digestive system. Top right: Experimental paradigm involving a range of decaying fruit for mechanical analysis. Bottom: Immunofluorescence stainings showing the expression of the transgenic 3xP3-RFP and generated pb/peb-split-GAL4 driving a UAS-myrGFP reporter in the taste organs, but not the DOG (left). With expression in the embryonic phase (right) mirroring that of the larva.
simon-sprecher.bsky.social
Thanks Matthias! “Sensing” food is a feast for the senses 😉👍
Reposted by Simon Sprecher
plosbiology.org
Sensing food is a complex multisensory experience. A study of food hardness preference in #FruitFly larvae by @simon-sprecher.bsky.social &co reveals that gustatory organ sensory neurons can perceive cues of both chemical & mechanical stimulation 🧪 @plosbiology.org plos.io/3CEv5FJ
Top left: Top—cartoon of larval food environment, showing a harder (fresh) fruit and a softer (ripe) fruit. Bottom—larval ingestion can be visualised by blue-dyed agarose present and visible in the digestive system. Top right: Experimental paradigm involving a range of decaying fruit for mechanical analysis. Bottom: Immunofluorescence stainings showing the expression of the transgenic 3xP3-RFP and generated pb/peb-split-GAL4 driving a UAS-myrGFP reporter in the taste organs, but not the DOG (left). With expression in the embryonic phase (right) mirroring that of the larva.
Reposted by Simon Sprecher
Reposted by Simon Sprecher
silkesachse.bsky.social
Dear colleagues fascinated by olfaction and taste! 👃🏾👅
We’ll organize the next ESITO (Symposium of Insect Taste and Olfaction) from September 19-24 2025 in Sardinia at the beautiful Hotel Cormoran again. We are currently updating the website and will start the registration soon! Please stay tuned!
Beach at Hotel Cormoran in Sardinia. Hotel Cormoran in Villasimius, Sardinia.
Reposted by Simon Sprecher
edrc2025.bsky.social
We are excited to announce the opening of registrations for the upcoming #EDRC2025 conference (25th-28th September 2025) in Alicante to showcase the latest advances in #Drosophila biology and technology edrc2025alicante.com
EDRC 2025 Alicante
edrc2025alicante.com
simon-sprecher.bsky.social
To understand how brains do their amazing job, we ultimately need to know how they are wired up. This remains impossible in "large" brains, however FlyWire allows everyone to browse the fruit fly the connectome!
Here my take on what makes this so impacting-
www.tandfonline.com/doi/full/10....
Disentangling how the brain is wired
Published in Fly (Vol. 19, No. 1, 2025)
www.tandfonline.com
simon-sprecher.bsky.social
And so much science still to do 👍😉
Reposted by Simon Sprecher
fly-eds.bsky.social
The European Drosophila Society is delighted to join Bluesky! Follow us for the latest European fly news.
#EDRC2025
#Drosophila
#Drosofeed
European Drosophila Society logo: a stylised fly on blue background with yellow stars created by MC Diaz de la Loza.
simon-sprecher.bsky.social
Very cool work: interfere between classic and operant conditioning!
mosheparnas.bsky.social
1/ How do animals integrate different forms of learning? Our
@eyalrozenfeld.bsky.social new study in Science Advances
shows that active mechanisms prevent the co-formation of competing memories. Here’s what we found! 🧵👇
science.org/doi/10.1126/...
simon-sprecher.bsky.social
That’s it! We’re obsolete …. 😉
simon-sprecher.bsky.social
There is indeed (but it is not filled with melted cheese - 🫕🫕) 😉
simon-sprecher.bsky.social
Sunrise at the Lake of Gruyère; winter has arrived in Fribourg
simon-sprecher.bsky.social
Some news about one of my favorite critters: Xenoturbella!
A most complete version of its genome provides insight into a surprisingly „complex“ gene repertoire and molecular features- and raises questions on its phylogenetic position-
Congrats to an exciting paper!
elifesciences.org/digests/9494...
eLife Science Digests
Cutting jargon and putting research in context, digests showcase some of the latest articles published in eLife.
elifesciences.org
simon-sprecher.bsky.social
😂😂
raccoonologist.bsky.social
I’m sorry, Europe, but without the cancer colours these SIMPLY ARE NOT FROOT LOOPS
A box of Froot Loops with yellow and purple cereal pictured, there is text reading “no artificial colours no artificial flavours”
Reposted by Simon Sprecher
annikabarber.bsky.social
And this insect genetics starter pack has a lot of Drosophilists, along with other Good Bugs (they're all good bugs). bsky.app/starter-pack...
Reposted by Simon Sprecher
simon-sprecher.bsky.social
Very cool- one day on Bluesky and the feed is getting busy- the „starterpack“ approach works well 👍👍👍