Simone Papa
@simonepapa.bsky.social
Phd in Neuroscience (ETH) Neurobehavioural Dynamics Lab
Neurobiology - Sapienza University | EMBL
- Visual Systems Neuroscience;
- Neurophysiology and functional neuroanatomy (Visuomotor System);
- Computational Neuroscience (Modelling & ANN)
Neurobiology - Sapienza University | EMBL
- Visual Systems Neuroscience;
- Neurophysiology and functional neuroanatomy (Visuomotor System);
- Computational Neuroscience (Modelling & ANN)
I am pleased to share that I have commenced my Doctor of Philosophy (PhD) program in Neuroscience at @ethz.ch Eidgenössische Technische Hochschule Zürich!
#ETH #PhD #Neuroscience #DHest
#ETH #PhD #Neuroscience #DHest
January 12, 2026 at 4:06 PM
I am pleased to share that I have commenced my Doctor of Philosophy (PhD) program in Neuroscience at @ethz.ch Eidgenössische Technische Hochschule Zürich!
#ETH #PhD #Neuroscience #DHest
#ETH #PhD #Neuroscience #DHest
Non-invasive temporal interference #stimulation can quiet deep epileptic networks.
In MTLE patients, TI targeting the #hippocampus reduced seizure biomarkers and limited spread, with lasting effects beyond stimulation, offering a promising option for drug-resistant #epilepsy without surgery.
In MTLE patients, TI targeting the #hippocampus reduced seizure biomarkers and limited spread, with lasting effects beyond stimulation, offering a promising option for drug-resistant #epilepsy without surgery.
January 6, 2026 at 8:46 PM
Non-invasive temporal interference #stimulation can quiet deep epileptic networks.
In MTLE patients, TI targeting the #hippocampus reduced seizure biomarkers and limited spread, with lasting effects beyond stimulation, offering a promising option for drug-resistant #epilepsy without surgery.
In MTLE patients, TI targeting the #hippocampus reduced seizure biomarkers and limited spread, with lasting effects beyond stimulation, offering a promising option for drug-resistant #epilepsy without surgery.
A new #Brain study shows cortico-basal oscillations track real-world movement in #Parkinson’s patients with #DBS.
These rhythms change predictably during daily actions. Measuring brain signals in natural settings could enable adaptive, personalized stimulation beyond the clinic (Michael S Oku)
These rhythms change predictably during daily actions. Measuring brain signals in natural settings could enable adaptive, personalized stimulation beyond the clinic (Michael S Oku)
January 3, 2026 at 10:12 PM
A new #Brain study shows cortico-basal oscillations track real-world movement in #Parkinson’s patients with #DBS.
These rhythms change predictably during daily actions. Measuring brain signals in natural settings could enable adaptive, personalized stimulation beyond the clinic (Michael S Oku)
These rhythms change predictably during daily actions. Measuring brain signals in natural settings could enable adaptive, personalized stimulation beyond the clinic (Michael S Oku)
A colleague’s new study in #Biomolecules compares β- and γ-synuclein aggregation across vertebrates.
It reveals species-specific differences in aggregation propensity and copper sensitivity, offering new insights into #synuclein dynamics and mechanisms.
www.mdpi.com/2218-273X/15...
It reveals species-specific differences in aggregation propensity and copper sensitivity, offering new insights into #synuclein dynamics and mechanisms.
www.mdpi.com/2218-273X/15...
January 3, 2026 at 7:24 PM
A colleague’s new study in #Biomolecules compares β- and γ-synuclein aggregation across vertebrates.
It reveals species-specific differences in aggregation propensity and copper sensitivity, offering new insights into #synuclein dynamics and mechanisms.
www.mdpi.com/2218-273X/15...
It reveals species-specific differences in aggregation propensity and copper sensitivity, offering new insights into #synuclein dynamics and mechanisms.
www.mdpi.com/2218-273X/15...
A new #fluorescent sensor, iGluSnFR3, reveals #glutamate release at #synapses in real time 🧠✨
Developed by teams from the Allen Institute, HHMI, and UC San Diego, it makes the brain’s fastest signals visible, enabling deeper insight into how #neurons communicate across networks.
Developed by teams from the Allen Institute, HHMI, and UC San Diego, it makes the brain’s fastest signals visible, enabling deeper insight into how #neurons communicate across networks.
January 3, 2026 at 7:15 PM
A new #fluorescent sensor, iGluSnFR3, reveals #glutamate release at #synapses in real time 🧠✨
Developed by teams from the Allen Institute, HHMI, and UC San Diego, it makes the brain’s fastest signals visible, enabling deeper insight into how #neurons communicate across networks.
Developed by teams from the Allen Institute, HHMI, and UC San Diego, it makes the brain’s fastest signals visible, enabling deeper insight into how #neurons communicate across networks.
Season’s greetings from the microscopy world!
A festive YFP-labeled neuron lights up an enlightened mouse brain from the Noé Rodriguez collection, with creative work by Stanislav Pelekhov (Ksena Longrin)
Happy holidays! #microscopy #neuroscience #neuron
A festive YFP-labeled neuron lights up an enlightened mouse brain from the Noé Rodriguez collection, with creative work by Stanislav Pelekhov (Ksena Longrin)
Happy holidays! #microscopy #neuroscience #neuron
December 23, 2025 at 4:05 PM
Season’s greetings from the microscopy world!
A festive YFP-labeled neuron lights up an enlightened mouse brain from the Noé Rodriguez collection, with creative work by Stanislav Pelekhov (Ksena Longrin)
Happy holidays! #microscopy #neuroscience #neuron
A festive YFP-labeled neuron lights up an enlightened mouse brain from the Noé Rodriguez collection, with creative work by Stanislav Pelekhov (Ksena Longrin)
Happy holidays! #microscopy #neuroscience #neuron
I attended “Spremuta di Cervelli” on #education and the future of learning, focusing on how #neuroscience and #AI intersect.
The discussion explored how attention, memory, motivation, and emotion shape learning, and how algorithms may transform #teaching without losing sight of #brain complexity.
The discussion explored how attention, memory, motivation, and emotion shape learning, and how algorithms may transform #teaching without losing sight of #brain complexity.
December 20, 2025 at 2:58 PM
I attended “Spremuta di Cervelli” on #education and the future of learning, focusing on how #neuroscience and #AI intersect.
The discussion explored how attention, memory, motivation, and emotion shape learning, and how algorithms may transform #teaching without losing sight of #brain complexity.
The discussion explored how attention, memory, motivation, and emotion shape learning, and how algorithms may transform #teaching without losing sight of #brain complexity.
Over a year of #FluorescenceFriday showcased biology in true 3D, from intact human tissues to neural and immune networks, tumors, and vasculature.
Structure, context, and relationships. In biology, context isn’t optional, it’s ground truth (Alpenglow Biosciences)
Structure, context, and relationships. In biology, context isn’t optional, it’s ground truth (Alpenglow Biosciences)
December 20, 2025 at 2:53 PM
Over a year of #FluorescenceFriday showcased biology in true 3D, from intact human tissues to neural and immune networks, tumors, and vasculature.
Structure, context, and relationships. In biology, context isn’t optional, it’s ground truth (Alpenglow Biosciences)
Structure, context, and relationships. In biology, context isn’t optional, it’s ground truth (Alpenglow Biosciences)
#Bioinformatics is a fast-growing market: $10.1B in 2022, projected to reach $18.7B by 2027 (13% CAGR)
Growth is driven by public and private funding, while high equipment costs remain a barrier. Emerging markets offer major opportunities, and data security will define long-term winners.
Growth is driven by public and private funding, while high equipment costs remain a barrier. Emerging markets offer major opportunities, and data security will define long-term winners.
December 18, 2025 at 12:31 PM
#Bioinformatics is a fast-growing market: $10.1B in 2022, projected to reach $18.7B by 2027 (13% CAGR)
Growth is driven by public and private funding, while high equipment costs remain a barrier. Emerging markets offer major opportunities, and data security will define long-term winners.
Growth is driven by public and private funding, while high equipment costs remain a barrier. Emerging markets offer major opportunities, and data security will define long-term winners.
This Thursday we’re hosting an event on #Education at the intersection of #neuroscience and #AI.
We’ll explore how brains and algorithms learn through error, feedback, and adaptation, and what this means for attention, memory, teaching practices, and the future role of educators.
We’ll explore how brains and algorithms learn through error, feedback, and adaptation, and what this means for attention, memory, teaching practices, and the future role of educators.
December 16, 2025 at 5:47 PM
This Thursday we’re hosting an event on #Education at the intersection of #neuroscience and #AI.
We’ll explore how brains and algorithms learn through error, feedback, and adaptation, and what this means for attention, memory, teaching practices, and the future role of educators.
We’ll explore how brains and algorithms learn through error, feedback, and adaptation, and what this means for attention, memory, teaching practices, and the future role of educators.
Researchers from the Allen Institute and Japan’s University of Electro-Communications used supercomputer Fugaku to simulate the full mouse cortex, 10M neurons and 26B synapses.
Built on open data, this virtual brain lets scientists explore how disorders emerge.
alleninstitute.org/news/one-of-...
Built on open data, this virtual brain lets scientists explore how disorders emerge.
alleninstitute.org/news/one-of-...
December 16, 2025 at 5:38 PM
Researchers from the Allen Institute and Japan’s University of Electro-Communications used supercomputer Fugaku to simulate the full mouse cortex, 10M neurons and 26B synapses.
Built on open data, this virtual brain lets scientists explore how disorders emerge.
alleninstitute.org/news/one-of-...
Built on open data, this virtual brain lets scientists explore how disorders emerge.
alleninstitute.org/news/one-of-...
A new study introduces high-plex spatial RNA imaging in a single round using color-intensity barcodes and standard microscopes, enabling scalable transcript mapping.
Open textbook Principles of Light Microscopy, accessed over 44,000 times (Volodymyr Nechyporuk-Zloy).
www.nature.com/articles/s41...
Open textbook Principles of Light Microscopy, accessed over 44,000 times (Volodymyr Nechyporuk-Zloy).
www.nature.com/articles/s41...
December 13, 2025 at 6:45 PM
A new study introduces high-plex spatial RNA imaging in a single round using color-intensity barcodes and standard microscopes, enabling scalable transcript mapping.
Open textbook Principles of Light Microscopy, accessed over 44,000 times (Volodymyr Nechyporuk-Zloy).
www.nature.com/articles/s41...
Open textbook Principles of Light Microscopy, accessed over 44,000 times (Volodymyr Nechyporuk-Zloy).
www.nature.com/articles/s41...
A new study shows motor cortex stimulation eases chronic pain not via motor circuits, but through non-motor networks in the precentral gyrus.
nTMS mapping can target these regions precisely, enabling more personalized and effective treatments for pain. (Nicolas Hubacz, M.S)
#ChronicPain #TMS
nTMS mapping can target these regions precisely, enabling more personalized and effective treatments for pain. (Nicolas Hubacz, M.S)
#ChronicPain #TMS
December 13, 2025 at 6:43 PM
A new study shows motor cortex stimulation eases chronic pain not via motor circuits, but through non-motor networks in the precentral gyrus.
nTMS mapping can target these regions precisely, enabling more personalized and effective treatments for pain. (Nicolas Hubacz, M.S)
#ChronicPain #TMS
nTMS mapping can target these regions precisely, enabling more personalized and effective treatments for pain. (Nicolas Hubacz, M.S)
#ChronicPain #TMS
I attended “Brain Aging - How time shapes the brain,” exploring how aging alters memory, attention, and connectivity, while plasticity and circuit reorganization support resilience👨🦳🧠.
#BrainAging
#BrainAging
December 13, 2025 at 6:39 PM
I attended “Brain Aging - How time shapes the brain,” exploring how aging alters memory, attention, and connectivity, while plasticity and circuit reorganization support resilience👨🦳🧠.
#BrainAging
#BrainAging
Attended the seminar “What can we learn from stochastic parrots?” at UPF Barcelona, great insights on LLMs and cognition (Jarosław R. Lelonkiewicz).
Also visited IMIM’s Neurosciences Department, focused on mental and neurodegenerative disorders and the misuse of psychoactive substances.
#neuro
Also visited IMIM’s Neurosciences Department, focused on mental and neurodegenerative disorders and the misuse of psychoactive substances.
#neuro
December 3, 2025 at 12:08 AM
Attended the seminar “What can we learn from stochastic parrots?” at UPF Barcelona, great insights on LLMs and cognition (Jarosław R. Lelonkiewicz).
Also visited IMIM’s Neurosciences Department, focused on mental and neurodegenerative disorders and the misuse of psychoactive substances.
#neuro
Also visited IMIM’s Neurosciences Department, focused on mental and neurodegenerative disorders and the misuse of psychoactive substances.
#neuro
The inflammatory reflex shows how the brain regulates immunity through the vagus nerve: signals reach the spleen, activate T cells, and release acetylcholine to reduce TNF-α.
Inflammation isn’t only chemical, it’s electrical, with the brain telling the immune system when to calm down (James Durham)
Inflammation isn’t only chemical, it’s electrical, with the brain telling the immune system when to calm down (James Durham)
November 27, 2025 at 1:37 PM
The inflammatory reflex shows how the brain regulates immunity through the vagus nerve: signals reach the spleen, activate T cells, and release acetylcholine to reduce TNF-α.
Inflammation isn’t only chemical, it’s electrical, with the brain telling the immune system when to calm down (James Durham)
Inflammation isn’t only chemical, it’s electrical, with the brain telling the immune system when to calm down (James Durham)
Researchers mapped the genetic architecture of the corpus callosum using an AI tool that detects it across MRI types. Studying 50k people, they identified genes shaping its size and links to neuropsychiatric disorders (by Anna Sara Liberati)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 26, 2025 at 10:26 AM
Researchers mapped the genetic architecture of the corpus callosum using an AI tool that detects it across MRI types. Studying 50k people, they identified genes shaping its size and links to neuropsychiatric disorders (by Anna Sara Liberati)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
New work shows that temporarily silencing the amblyopic #retina can reopen visual pathways in adults.
Restoration depends on T-type calcium channel–driven bursting, offering a potential therapy that avoids blocking the stronger eye (by Eveline Ruehlin).
neurosciencenews.com/vision-resto...
Restoration depends on T-type calcium channel–driven bursting, offering a potential therapy that avoids blocking the stronger eye (by Eveline Ruehlin).
neurosciencenews.com/vision-resto...
November 26, 2025 at 10:24 AM
New work shows that temporarily silencing the amblyopic #retina can reopen visual pathways in adults.
Restoration depends on T-type calcium channel–driven bursting, offering a potential therapy that avoids blocking the stronger eye (by Eveline Ruehlin).
neurosciencenews.com/vision-resto...
Restoration depends on T-type calcium channel–driven bursting, offering a potential therapy that avoids blocking the stronger eye (by Eveline Ruehlin).
neurosciencenews.com/vision-resto...
I attended a talk on how dopamine prediction-error mechanisms mirror the way modern algorithms learn, anticipate, and shape our desires.
We explored the links between reward, addiction, daily habits, and AI-from chocolate to notifications and emerging algorithmic “bubbles”.
#BrAIns #Dopamine
We explored the links between reward, addiction, daily habits, and AI-from chocolate to notifications and emerging algorithmic “bubbles”.
#BrAIns #Dopamine
November 25, 2025 at 11:10 AM
Stunning work from the Lichtman Lab & Google Connectomics: a true 3D EM reconstruction of a single cortical neuron, with every yellow dot marking a synapse.
AI tools trace thousands of spines, revealing the micro-architecture of cortical computation. One cell, an entire universe (Nicolas Hubacz)
AI tools trace thousands of spines, revealing the micro-architecture of cortical computation. One cell, an entire universe (Nicolas Hubacz)
November 25, 2025 at 11:08 AM
Stunning work from the Lichtman Lab & Google Connectomics: a true 3D EM reconstruction of a single cortical neuron, with every yellow dot marking a synapse.
AI tools trace thousands of spines, revealing the micro-architecture of cortical computation. One cell, an entire universe (Nicolas Hubacz)
AI tools trace thousands of spines, revealing the micro-architecture of cortical computation. One cell, an entire universe (Nicolas Hubacz)
Science communication is getting easier.
Francois El-Dahe used NotebookLM to generate an infographic from their paper on microglia in zebrafish brain repair, no edits, just minutes of work.
For those of us who aren’t designers, AI finally lets ideas take visual form.
#SciComm #AItools
Francois El-Dahe used NotebookLM to generate an infographic from their paper on microglia in zebrafish brain repair, no edits, just minutes of work.
For those of us who aren’t designers, AI finally lets ideas take visual form.
#SciComm #AItools
November 25, 2025 at 11:07 AM
Joined “Brain Rot, Digital Infodemia Consumes Attention”: a look at how the brain struggles with fragmented info while AI systems exploit attention.
A dive into how constant connectivity reshapes creativity, knowledge, and free thought. Attention, dopamine overload and memory effects.
#BrainJuice
A dive into how constant connectivity reshapes creativity, knowledge, and free thought. Attention, dopamine overload and memory effects.
#BrainJuice
November 16, 2025 at 4:06 PM
Joined “Brain Rot, Digital Infodemia Consumes Attention”: a look at how the brain struggles with fragmented info while AI systems exploit attention.
A dive into how constant connectivity reshapes creativity, knowledge, and free thought. Attention, dopamine overload and memory effects.
#BrainJuice
A dive into how constant connectivity reshapes creativity, knowledge, and free thought. Attention, dopamine overload and memory effects.
#BrainJuice
#AI is shifting from chatbots to systems that act. Autonomous agents, edge models, multimodal AI, scientific FMs, generative robotics, and new hardware will remake every industry.
The question is no longer what AI can say, but what it will build, fix, and discover next (Aaron Lax)
The question is no longer what AI can say, but what it will build, fix, and discover next (Aaron Lax)
November 14, 2025 at 9:51 PM
#AI is shifting from chatbots to systems that act. Autonomous agents, edge models, multimodal AI, scientific FMs, generative robotics, and new hardware will remake every industry.
The question is no longer what AI can say, but what it will build, fix, and discover next (Aaron Lax)
The question is no longer what AI can say, but what it will build, fix, and discover next (Aaron Lax)
A 2016 study created #bio-hybrid intelligence by guiding turtles with human EEG via a brain-computer interface, linking thought to instinct without implants.
Now applied to pigeons, rats, and robots, it explores co-adaptive human-machine systems and the future of bio-cognitive control (Aaron Lax)
Now applied to pigeons, rats, and robots, it explores co-adaptive human-machine systems and the future of bio-cognitive control (Aaron Lax)
November 11, 2025 at 2:04 PM
A 2016 study created #bio-hybrid intelligence by guiding turtles with human EEG via a brain-computer interface, linking thought to instinct without implants.
Now applied to pigeons, rats, and robots, it explores co-adaptive human-machine systems and the future of bio-cognitive control (Aaron Lax)
Now applied to pigeons, rats, and robots, it explores co-adaptive human-machine systems and the future of bio-cognitive control (Aaron Lax)
MIT researchers developed miBrains, 3D human brain tissue models integrating all major brain cell types.
Grown from donors’ stem cells, gene-editable, and scalable, they help study brain biology and diseases like Alzheimer’s in ways previous models couldn’t.
#miBrains #Alzheimer’s #Cells
Grown from donors’ stem cells, gene-editable, and scalable, they help study brain biology and diseases like Alzheimer’s in ways previous models couldn’t.
#miBrains #Alzheimer’s #Cells
November 11, 2025 at 1:59 PM
MIT researchers developed miBrains, 3D human brain tissue models integrating all major brain cell types.
Grown from donors’ stem cells, gene-editable, and scalable, they help study brain biology and diseases like Alzheimer’s in ways previous models couldn’t.
#miBrains #Alzheimer’s #Cells
Grown from donors’ stem cells, gene-editable, and scalable, they help study brain biology and diseases like Alzheimer’s in ways previous models couldn’t.
#miBrains #Alzheimer’s #Cells