Soham Biswas
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sohambiswas.bsky.social
Soham Biswas
@sohambiswas.bsky.social
🧬 Bioinformatics | 🤖 ML/AI | 🧠 Genomics | Exploring the code of life with algorithms.
• Building models to decode biology 🧬 + 💻
• Occasionally ranting about pandas DataFrames 🐼

#Bioinformatics #MachineLearning #Genomics #SciComm
Reposted by Soham Biswas
1/2 Nataly Kravchenko-Balasha speaks to patient-specific approaches to identify steady-state dynamics and disease-deviation from that steady state. #ICSB2024 #systemsOncology #SystemsBiology doi.org/10.1186/s129...
Patient-specific signaling signatures predict optimal therapeutic combinations for triple negative breast cancer - Molecular Cancer
Triple negative breast cancer (TNBC) is a heterogeneous group of tumors which lack estrogen receptor, progesterone receptor, and HER2 expression. Targeted therapies have limited success in treating TN...
doi.org
December 5, 2024 at 4:21 AM
Reposted by Soham Biswas
📺 Just released by the BBC: a powerful video on the mission of the Internet Archive & the Wayback Machine.

“A time machine for the web,” preserving everything from lost government websites to books & records—before they vanish.

🔗 Explore: web.archive.org
🎥 Watch ⬇️ youtu.be/jh98N46DM5k
Can the Internet Archive save our digital history? | BBC News
YouTube video by BBC News
youtu.be
May 5, 2025 at 5:08 PM
Reposted by Soham Biswas
My book, An Intuitive Primer on Effective Functional Genomics Study Design, is published! I’d really appreciate it if you could help spread the word, and I’d love to hear your thoughts and feedback. I hope people will find it useful.

It’s available on Amazon: tinyurl.com/mx2hewen
January 17, 2025 at 2:30 PM
Reposted by Soham Biswas
Foldseek 10 with 4-27x (1-8 GPUs) faster search through MMseqs2-GPU. Faster ProstT5 protein search w/o structure prediction through multi-GPU/Apple Metal, new BFVD/BFMD databases and multimer clustering (preview).
💾 github.com/steineggerla...
📄 www.biorxiv.org/content/10.1...
🐍 available in bioconda
January 20, 2025 at 2:56 PM
Reposted by Soham Biswas
@charles_h_martin, not on #Bluesky, on #23andMe
March 27, 2025 at 4:56 PM
More effective personalized medicine 💊 approach than chemotherapy
March 27, 2025 at 6:31 PM
Reposted by Soham Biswas
A study in @nature.com by researchers at KI, @scilifelab.se and others reveals a new stress response mechanism in cells called split ISR (s-ISR). This may have implications for the treatment of #cancer and neurodegenerative diseases like leukodystrophies 🧪 #CellBiology www.nature.com/articles/s41...
Plasticity of the mammalian integrated stress response - Nature
A study describes the split integrated stress response, a cellular stress response mechanism characterized by reduced eIF2B activity without eIF2α phosphorylation, which activates the eIF4E–ATF4–PCK2 ...
www.nature.com
March 27, 2025 at 11:12 AM
Reposted by Soham Biswas
In clinical settings, even small discrepancies in genomes can lead to misdiagnosis or overlooked variants.

Find out how refget Sequence Collections, a new @ga4gh.org approved standard, can help ensure consistent reference genome usage.

www.ebi.ac.uk/about/news/t...
GA4GH announces refget Sequence Collections
The new GA4GH refget Sequence Collections helps streamline reference genome management.
www.ebi.ac.uk
March 27, 2025 at 3:05 PM