Benedikt Strunz
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strunzb.bsky.social
Benedikt Strunz
@strunzb.bsky.social
28 followers 58 following 0 posts
Virologist/Immunologist, MD PhD, based at Karolinska Institute/University Hospital. Excited about research, with special interest in reproduction immunology and antiviral immune responses
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Reposted by Benedikt Strunz
labwaggoner.bsky.social
HIV can take several mutational pathways to become resistant to lenacapavir, each with distinct resistance and fitness profiles
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
January 8, 2026 at 5:07 AM
Reposted by Benedikt Strunz
labwaggoner.bsky.social
Virus-specific CD8+ tissue-resident memory T cells trigger epithelial antiviral defenses via IFNγ @cp-immunity.bsky.social @emoryuniversity.bsky.social
www.cell.com/immunity/ful...
November 26, 2025 at 8:35 PM
Reposted by Benedikt Strunz
josiebryant.bsky.social
Really pleased to share the first paper to come out of the lab.
We found that hospital patients were frequently colonised with P. aeruginosa and that the same clone was shared between the gut and the lung.
The phylogenies indicate that the clones moved from lung->gut

www.nature.com/articles/s41...
High frequency body site translocation of nosocomial Pseudomonas aeruginosa - Nature Communications
Here, the authors report within-host diversity and body site translocation dynamics in hospital samples of Pseudomonas aeruginosa and reveal that body site sharing was likely due to within-patient tra...
www.nature.com
November 25, 2025 at 10:40 AM
Reposted by Benedikt Strunz
labwaggoner.bsky.social
Multiple LDLR family members act as entry receptors for yellow fever virus @nature.com
www.nature.com/articles/s41...
Multiple LDLR family members act as entry receptors for yellow fever virus - Nature
The low-density lipoprotein receptor family members LRP1, LRP4 and VLDLR are entry receptors for yellow fever virus.
www.nature.com
October 29, 2025 at 7:05 PM
Reposted by Benedikt Strunz
labwaggoner.bsky.social
Transient tissue residency and lymphatic egress define human CD56bright NK cell homeostasis @natimmunol.nature.com @Betts @ki.se @upenn.edu
www.nature.com/articles/s41...
Congrats on another great story, Annika and Niklas!
October 14, 2025 at 5:48 PM
Reposted by Benedikt Strunz
sanderlab.bsky.social
Impfung gegen Demenz? Ja, genau.
Die nächste große Studie, die klaren Zusammenhang zwischen Herpes Zoster (Gürtelrose) und erhöhtem Demezrisiko zeigt. Aber Impfung reduziert das Demenzrisiko deutlich.
Zwei Stiche für ein deutlich gesenktes Demenzrisiko.
Guter Deal!
www.nature.com/articles/s41...
a,b, Comparing dementia risk (cumulative hazard, y axis) over time (x axis) after (a) exposures of female individuals to the ZVL and (b) exposure of female individuals aged 80–89 years to the RZV showed a substantial association with a decreased dementia risk at 3 and 5 years after index date compared to the PPSV23. The postmatching cohort characteristics for comparisons shown in this figure are presented in Supplementary Table 25. The curves show the Nelson–Aalen estimates of the cumulative hazard function (y axis) over the follow-up period (x axis) with a 95% CI band (shaded areas around each curve) for each cohort being compared. Cumulative hazards at specific time points are compared between the cohorts based on RR using a two-sided chi-squared statistic with 1 degree of freedom without adjusting for multiple comparisons. Superscript letter ‘a’ indicates censored, cumulative numbers of individuals who were lost to follow-up or had died until each time point; superscript letter ‘b’ indicates cumulative numbers of individuals with the event of interest (dementia diagnosis) until each time point. NMD, normalized mean difference; RR, relative risk.
October 6, 2025 at 8:55 PM
Reposted by Benedikt Strunz
jem.org
Joshua Hatterschide @jhattz.bsky.social Liheng Yang, & Carolyn Coyne identify DUX4 as a master regulator of an antiviral program in trophoblasts, specifically targeting a prominent family of teratogenic viruses. rupress.org/jem/article/...
#InfectiousDisease #HostDefense #InnateImmunity #Virology
October 2, 2025 at 3:07 PM
Reposted by Benedikt Strunz
labwaggoner.bsky.social
Lung NR3C1+ and CXCR6high T cells distinguish immunopathogenesis of human emphysema www.nature.com/articles/s42... @francypolverino.bsky.social @bcmhouston.bsky.social
September 24, 2025 at 6:11 PM
Reposted by Benedikt Strunz
labwaggoner.bsky.social
Progression to rheumatoid arthritis in at-risk individuals is defined by systemic inflammation and by T and B cell dysregulation www.science.org/doi/10.1126/...
Progression to rheumatoid arthritis in at-risk individuals is defined by systemic inflammation and by T and B cell dysregulation
Individuals at risk for rheumatoid arthritis exhibit inflammation and immune dysregulation before and during transition to active disease.
www.science.org
September 24, 2025 at 7:46 PM
Reposted by Benedikt Strunz
labwaggoner.bsky.social
Rifampicin is more effective against biofilm infections because it targets biofilm-forming mutants that are highly resistant to other antibiotics @niaidnews.bsky.social
www.science.org/doi/10.1126/...
September 17, 2025 at 10:28 PM
Reposted by Benedikt Strunz
labwaggoner.bsky.social
NKp46 Recognizes the Hyphal Form of Candida albicans and Mediates Protective Antifungal Immunity @cp-iscience.bsky.social
www.cell.com/iscience/ful...
September 15, 2025 at 4:41 PM
Reposted by Benedikt Strunz
gesvirologie.bsky.social
🔬✨ Introducing: Expert Insights – the new seminar series by the Young Society for Virology!

We’ve combined the strengths of our previous “How to” seminar series and the GfV ROUND lunch discussions into one powerful format – Expert Insights.

1/n
August 25, 2025 at 1:54 PM
Reposted by Benedikt Strunz
labwaggoner.bsky.social
Single cell transcriptional landscape of liver transplant rejection reveals tissue persistence of clonally expanded, treatment-resistant T cells @cincyresearch.bsky.social @amjtransplant.bsky.social
www.sciencedirect.com/science/arti...
August 15, 2025 at 5:01 PM
Reposted by Benedikt Strunz
cidjournal.bsky.social
Cytomegalovirus vertical transmission rate according to IgG avidity value and valacyclovir treatment of maternal primary infection in the first trimester of pregnancy

✅ Just Accepted
#IDSky
Cytomegalovirus vertical transmission rate according to IgG avidity value and valacyclovir treatment of maternal primary infection in the first trimester of pregnancy
CMV serology in the first trimester (T1) of pregnancy relies on IgG and IgM testing, followed by IgG avidity measurement when both IgG and IgM are positive. Valacyclovir is proposed to prevent vertical transmission in maternal primary infection (MPI) during T1.
academic.oup.com
August 10, 2025 at 12:41 PM
Reposted by Benedikt Strunz
labwaggoner.bsky.social
Review @natrevimmunol.nature.com @yaelalippe.bsky.social @msdiamondlab.bsky.social
Innate immune responses to pathogens at the maternal–fetal interface
www.nature.com/articles/s41...
Innate immune responses to pathogens at the maternal–fetal interface - Nature Reviews Immunology
During pregnancy, innate immune mechanisms at the maternal–fetal interface are important for protecting the developing fetus from pathogens. However, excessive immune activation can be harmful to the ...
www.nature.com
June 18, 2025 at 7:21 PM
Reposted by Benedikt Strunz
labwaggoner.bsky.social
Ascites in patients with decompensated liver cirrhosis harbor a heterogenous subset of CD103+ NK cells that is likely induced by the cytokine milieu
onlinelibrary.wiley.com/doi/10.1002/... @eurjimmunol.bsky.social
June 13, 2025 at 10:30 PM
Reposted by Benedikt Strunz
labwaggoner.bsky.social
CD9 identifies and regulates IL-21 & IFN-γ-producing Tfh cells, shaping humoral immunity in infection and autoimmunity
papers.ssrn.com/sol3/papers....
CD9 Identifies and Regulates a Highly Functional T Follicular Helper (Tfh) Cell Subset Necessary for Promoting Antibodies During Infection
T follicular helper (Tfh) cells differentiate within T cell zones, B-cell follicles, and germinal centers (GCs), where they secrete cytokines such as IL-21 and
papers.ssrn.com
March 21, 2025 at 6:03 PM
Reposted by Benedikt Strunz
labwaggoner.bsky.social
REVIEW: Approaches to investigate tissue-resident innate lymphocytes metabolism at the single-cell level
www.nature.com/articles/s41...
@davidfinlaytcd.bsky.social
December 1, 2024 at 3:26 AM
Reposted by Benedikt Strunz
chillslincoln79.bsky.social
Atlas of the plasma proteome in health and disease in 53,026 adults 👩‍🔬🥼👨‍🔬🧪. #proteomics #proteome #plasma #MedSky 👇👇

www.cell.com/cell/fulltex...
Atlas of the plasma proteome in health and disease in 53,026 adults
A large-scale proteomics study involving 53,026 individuals maps 2,920 plasma proteins to 406 prevalent diseases, 660 incident diseases, and 986 health-related traits, identifying promising biomarkers...
www.cell.com
November 23, 2024 at 7:49 AM