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Sudarshan Krishnamurthy @sudkrishnamurthy.bsky.social · 3d

All of this will also eventually culminate in my life’s work to intervene on those social and structural determinants to improve health for all!

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Sud with his family — Sud’s dad is on his left, with Sud’s uncle to the extreme left. Sud’s aunt is on his right, with Sud’s uncle to her right. Sud’s partner, Bailey, is on the extreme right — far-left of the image.

Sud at one of their favorite breweries, Lesser-Known Beer Company, in front of barrels where beers are being aged, wearing a sash that reads “Ph.inisheD” and a decorative gold “PHD” sign hanging above!

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Sudarshan Krishnamurthy @sudkrishnamurthy.bsky.social · 3d

I’m excited to see the work from my dissertation get out there over the coming months, and to further build upon this work to illustrate the influence of the social and structural determinants of health on dementia.

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A picture of cinnabon delights bought for Sud by their partner, Bailey, with little celebratory PhD signs on toothpicks sticking out from it!

Sud along with their dissertation committee members, who could make it in person to the defense. Two of Sud’s committee members could only join virtually — Dr. Sarah Forrester and Dr. Chris Whitlow.

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Sudarshan Krishnamurthy @sudkrishnamurthy.bsky.social · 3d

Not a typical post (🧵) on here, but just over 6 months ago, I successfully defended my dissertation alongside friends, family, my committee, and many loved ones. It was a wonderful day, and I have so many people to thank for their support over the past 3 years and more!

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Front page of Sud’s dissertation titled ‘Investigating the Relationships of Place-based Social Determinants of Health and Structural Racism with Measures of Alzheimer’s Disease and Related Dementias”.

The rest of the text on the title page reads as follows:
BY
SUDARSHAN KRISHNAMURTHY
A Dissertation Submitted to the Graduate Faculty of
WAKE FOREST UNIVERSITY GRADUATE SCHOOL OF ARTS AND SCIENCES in Partial Fulfilment of the Requirements for the Degree of
DOCTOR OF PHILOSOPHY
Molecular Medicine and Translational Science
May 2025
Winston-Salem, North Carolina
Approved By:
Timothy M. Hughes, PhD, MPH, Advisor
James R. Bateman, MD, MPH, Chair
Sarah N. Forrester, PhD, MS
Da Ma, PhD
Ellen Quillen, PhD
Christopher Whitlow, MD, PhD

Sud standing in a dark blue suit and blue shirt grinning as he wears a sash that reads “Ph.inisheD”.

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Reposted by Sudarshan Krishnamurthy

Michael D. Green @michaeldgreen.com · Jul 22

Our new pre-print presents the reporting, and racial and ethnic diversity of 58,000+ studies in clinicaltrials.gov, the largest global clinical study registry. Reporting of race and ethnicity to the registry began in 2009, and we analyzed data through 2024 #MedSky

www.medrxiv.org/content/10.1...

Racial and Ethnic Diversity in Clinical Studies Reported to ClinicalTrials.gov, 2009-2024

Importance: A lack of transparent reporting of race and ethnicity in clinical research limits the ability to identify health inequities and evaluate to what extent clinical research includes diverse p...

www.medrxiv.org

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Reposted by Sudarshan Krishnamurthy

Jonathan Brisbon, MD @jbrisbon.bsky.social · Jun 25

Starting residency without money for rent or furniture or groceries until
I get my first paycheck mid July. I’m a physician and surgical resident who beat cancer. Please share and donate

Jonathan Brisbon, MD @jbrisbon.bsky.social · Jun 12

If you would like to donate to an incoming general surgery resident who lost his father after his first year of medical school, who also beat cancer, has food insecurity, & graduated without familial support. All contributions are for a security deposit & rent until I get my first paycheck mid July.

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Reposted by Sudarshan Krishnamurthy

Jonathan Brisbon, MD @jbrisbon.bsky.social · Jun 12

If you would like to donate to an incoming general surgery resident who lost his father after his first year of medical school, who also beat cancer, has food insecurity, & graduated without familial support. All contributions are for a security deposit & rent until I get my first paycheck mid July.

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Reposted by Sudarshan Krishnamurthy

Molly Shah @mommunism.bsky.social · Oct 7

I’m going to make individual posts for the Palestinian accounts I’m boosting today so they don’t get lost in a thread but if you are looking for them all in one place I’ll link them here 🔽

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Reposted by Sudarshan Krishnamurthy

Jonathan Brisbon, MD @jbrisbon.bsky.social · Jun 5

I fought cancer. I lost my dad. I became a doctor with no family support. Now I’m weeks away from residency with no housing, no groceries, and no paycheck until mid-July. I’ve come too far to fall now.
Please help.
📲 Venmo: @JBrisbon1181
🙏 gofund.me/850fc46c

#medsky #urosky #mdsky #orthosky

Donate to Help Dr. Brisbon with Housing & Food for Surgical Residency, organized by Jonathan Brisbon

My name is Dr. Jonathan Lee Brisbon, and I am humbly asking f… Jonathan Brisbon needs your support for Help Dr. Brisbon with Housing & Food for Surgical Residency

gofund.me

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Sudarshan Krishnamurthy @sudkrishnamurthy.bsky.social · Jun 3

This is so dystopian… 😭😭 I’m so sorry this happened! Truly, what does qualifying for the paramedics even mean?!

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Reposted by Sudarshan Krishnamurthy

Jay Lusk, MD, MBA @jayblusk.bsky.social · May 24

Proud to share my latest paper in @bmj.com www.bmj.com/content/389/.... Takeaways: Dementia incidence ⬇️, prevalence ⬆️, and dementia is unequally distributed. In an opinion article, I argue we need to redouble our efforts to manage multimorbidity across the life course: www.bmj.com/content/389/...

Incidence and prevalence of dementia among US Medicare beneficiaries, 2015-21: population based study

Objective To determine the incidence and prevalence of dementia in a nationally representative cohort of US Medicare beneficiaries, stratified by important subgroups. Design Population based study. ...

www.bmj.com

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Reposted by Sudarshan Krishnamurthy

Jack Tripper @chadstanton.blacksky.app · May 25

Public health for the people

Corey @kh0rish.bsky.social · May 16

How the fuck did I miss this

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Sudarshan Krishnamurthy @sudkrishnamurthy.bsky.social · May 24

I had to look back at our initial analytic plans and proposals that we drafted, and it was in August 2022 - it caught me off guard too! 😂

Absolutely - this project wouldn't have happened without help from @dusetzinas.bsky.social and Shelley (who isn't on Bluesky yet)! Can't thank them both enough!😊

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Sudarshan Krishnamurthy @sudkrishnamurthy.bsky.social · May 23

If you’ve made it this far and would like to learn more, go give it a read for yourself here: jamanetwork.com/journals/jam...

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Racial and Ethnic Disparities in Receipt of ERBB2-Targeted Therapy for Breast Cancer

This cohort study examines racial and ethnic disparities in the receipt of ERBB2 (formerly HER2 or HER2/neu)–targeted therapies and changes in receipt over time among Medicare beneficiaries with ERBB2...

jamanetwork.com

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Sudarshan Krishnamurthy @sudkrishnamurthy.bsky.social · May 23

I truly cannot thank this entire team enough for their help in getting this out! (@dusetzinas.bsky.social)

And a special thanks to my mentor, sponsor, and friend in this work, @uressien.bsky.social, for giving me the opportunity to lead this project after we first discussed it back in 2022!

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This image is a visual abstract for a paper titled ‘Racial and Ethnic Disparities in Receipt of ERBB2-Targeted Therapy for Breast Cancer, 2010-2020”. This was a Retrospective Cohort study using a SEER-Medicare Linked Dataset. The sample comprised 12,765 beneficiaries with ERBB2-positive breast cancer, and included those diagnosed from January 2010 to December 2020. The primary outcome of the study was receipt of ERBB2-targeted therapy in 12 months after diagnosis. The primary findings showed a) an increase in overall receipt of ERBB2-targeted therapies from 41.3% to 64.3% over time, and that b) Black & Hispanic patients had a lower likelihood of receipt than White patients in 2010-11, with no differences by 2018-19. The findings suggest a narrowing of racial and ethnic disparities in receipt of therapies over time among older Medicare beneficiaries with ERBB2-positive breast cancer. Future work is needed to understand the practices that resulted in the narrowing of disparities to develop implementation strategies and improve pharmacoequity in breast cancer care.

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Sudarshan Krishnamurthy @sudkrishnamurthy.bsky.social · May 23

Our biggest takeaway from these findings is that we must understand the practices that contributed to the narrowing of these disparities, so we may develop more implementation strategies towards improving equitable cancer care! 🎯

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Sudarshan Krishnamurthy @sudkrishnamurthy.bsky.social · May 23

Our main finding was a narrowing of racial and ethnic disparities from 2010 to 2019! 📉

In other words, although Black and Hispanic beneficiaries had lower rates of receipt of ERBB2/HER2-targeted therapies than white beneficiaries in 2010, this disparity was no longer seen in 2019.

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This figure, from the study being discussed, has a line graph of the percentages of beneficiaries receiving treatment by race and ethnicity between 2010 and 2019 in panel A. Below that, in panel B, is a forest plot of the likelihood of treatment by race and ethnicity from 2010 to 2019 from up to down. Both figure panels show a narrowing of disparities, with Black and Hispanic beneficiaries starting off at lower rates of receipt of ERBB2/HER2-targeted therapies in 2010-11, and these disparities not being observed in 2018-19.

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Sudarshan Krishnamurthy @sudkrishnamurthy.bsky.social · May 23

To help answer this question, we designed a retrospective cohort study using the SEER–Medicare linked dataset, where the primary outcome was receipt of ERBB2/HER2-targeted therapies in the 12 months after diagnosis, by race and ethnicity.

So, what did we find? ⁉️

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Sudarshan Krishnamurthy @sudkrishnamurthy.bsky.social · May 23

The main question we asked for this study: Among Medicare beneficiaries diagnosed with ERBB2/HER2–positive breast cancer from 2010-19, are racial/ethnic disparities associated with receipt of ERBB2-targeted therapies, and do these trends change over time? 🤔

🔗: jamanetwork.com/journals/jam...

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Racial and Ethnic Disparities in Receipt of ERBB2-Targeted Therapy for Breast Cancer

This cohort study examines racial and ethnic disparities in the receipt of ERBB2 (formerly HER2 or HER2/neu)–targeted therapies and changes in receipt over time among Medicare beneficiaries with ERBB2...

jamanetwork.com

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Sudarshan Krishnamurthy @sudkrishnamurthy.bsky.social · May 23

Sharing a short thread here on our recent publication from earlier this month. This project was an incredible team effort, and truly would not have been possible without every co-author on this all-⭐ team!

Go give it a read here if interested: jamanetwork.com/journals/jam...

A short 🧵:

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Reposted by Sudarshan Krishnamurthy

Michael D. Green @michaeldgreen.com · May 20

Turned 26 today and recently finished my 4th year of my PhD program, so I wrote a new blog where I did some reflecting on the moment we are in.

Compared to when I applied to grad school in 2020, this is nowhere near what I would’ve predicted. Read here:

open.substack.com/pub/notbeing...

$In this moment, we have an unraveling of biomedical research infrastructure that not only is impacting my own training and research ability, but the future of scientific research. Many of the conversations I've had recently are about pivoting research focus. If I could go back into the future to newly admitted Ph.D. student Michael Green, the most straight forward advice would be to pursue something "non-controversial' so he could position himself for a career to pursue science that the current administration deems "non-controversial'. Avoiding controversy is not why I decided to pursue a Ph.D. in Population Health Sciences focusing on how people are socially treated in health systems. The definition of controversy is also constantly changing, so if avoiding controversy is your guiding framework, your target will be very unstable. I am pursuing this path because I have lived experience where my family members suffered because they feel like they were mistreated and/or unwelcome in healthcare spaces. In this moment, their experiences and trust in health systems are even more fractured than before. Simply pivoting from that work would not help them, so I cannot pivot from the greater mission, given that mission is core to my identity. Science is centered on controversy, we ask questions, run experiments, and make claims based on those experiments. Despite the pivot in how we support (or choose not to support) healthcare research, since I believe the new chaos will not work, we still need people in place to propose new solutions. I am concerned about people who hap-hazardously pivot from their alleged principles. At the same time I understand that the compensation you get in academia is well under corresponding positions in industry or another field. If the mission driven nature of academia is lost, and your ability to choose what you pursue based on your principles is lost, weathering the storm is a lot easier in places where you will make far more money or have less …$

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Reposted by Sudarshan Krishnamurthy

vee.soy @vashetc.bsky.social · May 10

Donate to my fundraiser if you’d like to help an exhausted girl out <3 meanwhile I’m going to nap and cry ok ty bai

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Sudarshan Krishnamurthy @sudkrishnamurthy.bsky.social · May 15

This sounds incredible - thanks for leading this! I couldn’t make it to SGIM this year, but would love to use any workshop resources that you may be able to share! ☺️

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Sudarshan Krishnamurthy @sudkrishnamurthy.bsky.social · May 6

If folks aren’t following this yet, you can keep an eye on this link for updates. The situation between India and Pakistan is escalating rapidly at the moment…

www.aljazeera.com/news/liveblo...

India fires missile barrage into Pakistan as war fears surge

Indian army launches ‘Operation Sindoor’, hitting nine sites in Pakistan and Pakistan-administered Kashmir.

www.aljazeera.com

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Sudarshan Krishnamurthy @sudkrishnamurthy.bsky.social · May 5

In the meantime, if you’d like to give it a read, here’s the link to the article!

jamanetwork.com/journals/jam...

#Pharmacoequity

Racial and Ethnic Disparities in Receipt of ERBB2-Targeted Therapy for Breast Cancer

This cohort study examines racial and ethnic disparities in the receipt of ERBB2 (formerly HER2 or HER2/neu)–targeted therapies and changes in receipt over time among Medicare beneficiaries with ERBB2...

jamanetwork.com

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