#DBfeature

Mesenchymal cell contractility regulates villus morphogenesis and intestinal architecture

by Taylor Hinnant @taylorhinnant.bsky.social , Caroline Joo, Terry Lechler @terrylechler.bsky.social

www.sciencedirect.com/science/arti...

Happy Birthday, Rosalind Franklin. She captured an X-ray diffraction image of DNA and stated that a helical structure was probable. Watson and Crick then created a detailed model based on her results. They initially received credit for the discovery and were awarded the Nobel Prize after her death.🧪

ACTION ITEM-----ACTION ITEM

Implementation of Schedule F

This is what a lot of us have been worried about.

This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.

BUT THERE IS A COMMENT PERIOD...

1/n

Developmental biology research leads to fundamental discoveries for biomedical research.
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Cancer. Ellisen 1991 PMID 1831692; Hahn 1996 8647801; Johnson 1996 8658145; Tapon 2002 12202036
Hippo image 24336504
HH image bit.ly/3DoHIFl
Notch image 23213460

@socdevbio.bsky.social

Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...

Developmental biology research leads to fundamental discoveries for biomedical research. Pluripotent Stem Cells. Kleinsmith & Pierce, 1964. PMID: 14234000. Mouse image from Wikipedia. @socdevbio.bsky.social 4/12

Developmental biology research leads to fundamental discoveries for biomedical research. Cell Reprogramming. Gurdon 1962. PMID: 13951335. Oocyte image by Brandy Walker and Amaya Moss. Tadpole line drawing from
@xenbase.bsky.social @socdevbio.bsky.social
1/12

Developmental biology research leads to fundamental discoveries for biomedical research. Epithelial to Mesenchymal Transition. Greenburg & Hay, 1982. PMID: 7142291. Chick embryo image by Debra Cebra-Thomas.
@socdevbio.bsky.social 7/12

Developmental biology research leads to fundamental discoveries for biomedical research. In Situ Hybridization. Gall & Pardue, 1969. PMID: 4895535. Frog image by Brandy Walker (Rachel Miller Lab). @socdevbio.bsky.social 5/12

Apparently, the CDC are going to investigate the link between vaccines and autism again. Total waste of resources when it has already been conclusively shown that there is no link.
www.youtube.com/watch?v=H_w7...

Another critical tool taken down by the admin but preserved for the American people: FEMA’s Future Risk Index. It shows how much climate change will cost our communities (actual $ figures!)—no wonder the admin felt threatened.

fulton-ring.github.io/nri-future-r...

#FEMA #risk #data #climate

Join us today, in Raleigh NC and around the nation, as we remind our communities what science brings to the nation--solutions to our toughest challenges, new cures for disease and good jobs that pay a living wage
standupforscience2025.org

By @katherinejwu.com

"The NIH... supported 99 percent of the drugs approved in the U.S. from 2010 to 2019. The agency has had a hand in “nearly all of our major medical breakthroughs over the past several decades,”

The NIH is in a struggle for its (and our) lives. This is existential to America:

Life-saving research at St. Jude is made possible by these grants, which allow scientists to find new treatments and preventative measures.

Learn more from Dr. Roberts on the effects of cuts in NIH research grants: ow.ly/yEr950UXhBe

NEW: In a further sign of turmoil at the NIH, Mike Lauer, who oversees the agency's $39 billion extramural budget that goes to research outside the NIH, has resigned effective tomorrow.

This comes after top NIH official Larry Tabak abruptly retired yesterday.

Gift link
www.nytimes.com/2025/02/18/u...

My most recent article published with the Lechler Lab. We offer insights into the role of the mesenchyme during intestinal villi development. "Mesenchymal cell contractility regulates villus morphogenesis and intestinal architecture": www.sciencedirect.com/science/arti...

PLOS Genetics: dx.plos.org/10.1371/jour...